Association of working hours with biological indices related to the cardiovascular system among engineers in a machinery manufacturing company.

A field survey of 278 engineers (20-59 years) in a machinery manufacturing company was conducted to investigate the association of working hours with biological indices related to the cardiovascular system (heart rate variability, blood pressure and serum levels of magnesium, dehydroepiandrosterone sulfate and cholesterol). Average working hours (defined as <"hours at workplace" + "half a commuting time">) and sleeping hours in this study were 60.2 +/- 6.3 hr/week and 6.6 +/- 0.8 hr/day respectively. There were no significant relationships between working hours and biological indices related to the cardiovascular system, but sleeping hours was closely related to working hours negatively. Furthermore, the serum DHEA-S level was significantly related to sleeping hours positively. Combining these two results, it appeared that long working hours might lower the serum DHEA-S level due to the reduction of sleeping hours.

[1]  Y. Kurokawa,et al.  Long commuting time, extensive overtime, and sympathodominant state assessed in terms of short-term heart rate variability among male white-collar workers in the Tokyo megalopolis. , 1998, Industrial health.

[2]  T Yamaji,et al.  Plasma dehydroepiandrosterone sulfate in normal and pathological conditions. , 1969, The Journal of clinical endocrinology and metabolism.

[3]  N Hisanaga,et al.  Effect of working hours on biological functions related to cardiovascular system among salesmen in a machinery manufacturing company. , 1998, Industrial health.

[4]  C. Kirschbaum,et al.  Effects of dehydroepiandrosterone replacement in elderly men on event-related potentials, memory, and well-being. , 1998, The journals of gerontology. Series A, Biological sciences and medical sciences.

[5]  E. Barrett-Connor,et al.  A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease. , 1986, The New England journal of medicine.

[6]  S. Yen,et al.  Activation of immune function by dehydroepiandrosterone (DHEA) in age-advanced men. , 1997, The journals of gerontology. Series A, Biological sciences and medical sciences.

[7]  S. Kagamimori,et al.  Working hours as a risk factor for acute myocardial infarction in Japan: case-control study , 1998, BMJ.

[8]  N. Orentreich,et al.  Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. , 1984, The Journal of clinical endocrinology and metabolism.

[9]  E. Barrett-Connor,et al.  The Epidemiology of DHEAS and Cardiovascular Disease , 1995, Annals of the New York Academy of Sciences.