Using immersive virtual reality to test allocentric spatial memory impairment following unilateral temporal lobectomy

Immersive virtual reality was used to investigate spatial memory in 17 right and 19 left unilateral temporal lobectomy patients and 18 control subjects. The subjects were administered a task consisting of a virtual room and table with radially arranged ‘shells’ on top. The subjects moved around the table and had to find a blue cube, which was under one of the shells. On subsequent searches, the cube moved to a new location and the subject had to find it whilst avoiding the previous location, and so on until all locations had been used. A selective deficit was observed in the right temporal lobectomy group only, linking allocentric memory to the function of the right hippocampal formation.