Novel mobility test to assess functional vision in patients with inherited retinal dystrophies

This novel endpoint tracks functional vision changes in patients with inherited retinal dystrophies (IRDs) over time.

[1]  Gislin Dagnelie,et al.  Orientation and Mobility Assessment in Retinal Prosthetic Clinical Trials , 2012, Optometry and vision science : official publication of the American Academy of Optometry.

[2]  E.W. Hill,et al.  Mobility in Individuals with Moderate Visual Impairments , 1990 .

[3]  J. Lovie-Kitchin,et al.  What areas of of the visual field are important for mobility in low vision patients , 1990 .

[4]  Stacey George,et al.  Vision-Related Quality of Life in Patients with Complete Homonymous Hemianopia Post Stroke , 2009, Topics in stroke rehabilitation.

[5]  C I Howarth,et al.  The efficiency and walking speed of visually impaired people. , 1986, Ergonomics.

[6]  Shirin E. Hassan,et al.  Visual Field Size Criteria for Mobility Rehabilitation Referral , 2010, Optometry and vision science : official publication of the American Academy of Optometry.

[7]  Kathleen A. Marshall,et al.  Safety and efficacy of gene transfer for Leber's congenital amaurosis. , 2008, The New England journal of medicine.

[8]  Gang Luo,et al.  Evaluation of a Portable Collision Warning Device for Patients With Peripheral Vision Loss in an Obstacle Course. , 2015, Investigative ophthalmology & visual science.

[9]  Celia S. Chen,et al.  Functional improvements following the use of the NVT Vision Rehabilitation program for patients with hemianopia following stroke. , 2012, NeuroRehabilitation.

[10]  J. Lovie-Kitchin,et al.  Mobility performance with retinitis pigmentosa , 1997 .

[11]  A. Munnich,et al.  Leber congenital amaurosis. , 1999, Molecular genetics and metabolism.

[12]  Jan E Lovie-Kitchin,et al.  Visual Function, Visual Attention, and Mobility Performance in Low Vision , 2008, Optometry and vision science : official publication of the American Academy of Optometry.

[13]  I. Bailey,et al.  Visual Factors and Orientation‐Mobility Performance , 1982, American journal of optometry and physiological optics.

[14]  S. Haymes,et al.  Mobility of People with Retinitis Pigmentosa as a Function of Vision and Psychological Variables , 1996, Optometry and vision science : official publication of the American Academy of Optometry.

[15]  Kathleen A. Marshall,et al.  Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial , 2017, The Lancet.

[16]  K. Turano,et al.  Traditional Measures of Mobility Performance and Retinitis Pigmentosa , 1998, Optometry and vision science : official publication of the American Academy of Optometry.

[17]  W. Hauswirth,et al.  Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium. , 2015, Investigative ophthalmology & visual science.

[18]  J. L. Elliott,et al.  Visual Correlates of Mobility in Real World Settings in Older Adults with Low Vision , 1998, Optometry and vision science : official publication of the American Academy of Optometry.

[19]  Jean Bennett,et al.  Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial , 2016, The Lancet.

[20]  Christian J Foy Does mobility performance of visually impaired adults improve immediately after orientation and mobility training? , 2002, Optometry and vision science : official publication of the American Academy of Optometry.

[21]  Kathleen A. Marshall,et al.  Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial , 2009, The Lancet.