Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1mut at the 'aggrecanase' and the MMP sites. Characterization of MT1-MMP catabolic activities on the interglobular domain of aggrecan.
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B. Caterson | E. Bartnik | C. Hughes | H. Tschesche | F. Büttner | D. Margerie | A. Lichte | F. Büttner