Computational meta‐analysis of statistical parametric maps in major depression

Several neuroimaging meta‐analyses have summarized structural brain changes in major depression using coordinate‐based methods. These methods might be biased toward brain regions where significant differences were found in the original studies. In this study, a novel voxel‐based technique is implemented that estimates and meta‐analyses between‐group differences in grey matter from individual MRI studies, which are then applied to the study of major depression.

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