1,25-dihydroxyvitamin D3 receptors in human leukocytes.

A 1,25-dihydroxyvitamin D3 receptor macromolecule was detected in peripheral mononuclear leukocytes from normal humans. This macromolecule was found to be present in monocytes but absent from normal resting peripheral B and T lymphocytes. However, it was present in established lines of malignant B, T, and non-B, non-T human lymphocytes, as well as in T and B lymphocytes obtained from normal humans and activated in vitro.

[1]  S. Ferrone,et al.  T lymphocyte-mediated cytotoxicity against autologous EBV-genome-bearing B cells. , 1981, Journal of immunology.

[2]  W. Crosby,et al.  Cytochemical identification of monocytes and granulocytes. , 1971, American journal of clinical pathology.

[3]  I. Royston,et al.  Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin. , 1980, Journal of immunology.

[4]  G C Salzman,et al.  Cell classification by laser light scattering: identification and separation of unstained leukocytes. , 1975, Acta cytologica.

[5]  S. Manolagas,et al.  Studies of the internalization of vitamin D3 metabolites by cultured osteogenic sarcoma cells and their application to a non-chromatographic cytoreceptor assay for 1,25-dihydroxyvitamin D3. , 1980, Biochemical and biophysical research communications.

[6]  M. Haussler,et al.  1,25-Dihydroxyvitamin D3 receptor-like macromolecule in rat osteogenic sarcoma cell lines. , 1980, The Journal of biological chemistry.

[7]  E. Reinherz,et al.  A monoclonal antibody reactive with human peripheral blood monocytes. , 1980, Journal of immunology.

[8]  S. Lee,et al.  Reversible inhibition by interferon of the maturation of human peripheral blood monocytes to macrophages. , 1980, Cellular immunology.

[9]  C. Mogensen The glomerular permeability determined by dextran clearance using Sephadex gel filtration. , 1968, Scandinavian journal of clinical and laboratory investigation.

[10]  J. Ritz,et al.  Modulation of human acute lymphoblastic leukemia antigen induced by monoclonal antibody in vitro. , 1980, Journal of immunology.

[11]  J. Loutit,et al.  Osteoclasts derived from haematopoietic stem cells , 1980, Nature.

[12]  M. Greaves,et al.  Expression of an antigen associated with acute lymphoblastic leukemia in human leukemia-lymphoma cell lines. , 1978, Journal of the National Cancer Institute.

[13]  P. Nowell,et al.  Sequential proliferation induced in human peripheral blood lymphocytes by mitogen. II. Suppression by PHA-activated cells. , 1977, Journal of immunology.

[14]  T. Waldmann,et al.  Separation of human blood monocytes and lymphocytes on a continuous Percoll gradient. , 1980, Journal of immunological methods.

[15]  E. Martz,et al.  Simultaneous suppression of allogeneic cytolytic activity and stimulation of lectin-dependent cytolytic activity by con A. , 1978, Cellular immunology.

[16]  M. Haussler,et al.  Basic and clinical concepts related to vitamin D metabolism and action (second of two parts). , 1977, The New England journal of medicine.

[17]  E H Burger,et al.  In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytes , 1982, The Journal of experimental medicine.

[18]  Etsuko Abe,et al.  1α,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells , 1981 .