Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma
暂无分享,去创建一个
W. Klapper | A. López-Guillermo | G. Ott | S. Ogawa | R. Rosenquist | Kenichi Yoshida | P. Korkolopoulou | Marieluise Kirchner | L. Mansouri | G. Kanellis | T. Vassilakopoulos | A. Staiger | T. Schneider | B. Casadei | Y. Inoue | F. Briest | R. Hablesreiter | D. Sasca | Daniel Noerenberg | J. Weiner | Laura Wiegand | C. Hennch | Philipp Mertins | Ákos Nagy | Mike Hummel | Frederik Damm | Lars Bullinger | I. Anagnostopoulos | Arne Warth | Jose Nimo | J. Nimo
[1] T. Hsiau,et al. Inference of CRISPR Edits from Sanger Trace Data. , 2022, The CRISPR journal.
[2] L. Bullinger,et al. Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9 , 2021, Leukemia.
[3] D. Vignali,et al. Interferon-γ: teammate or opponent in the tumour microenvironment? , 2021, Nature Reviews Immunology.
[4] F. Klauschen,et al. Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories , 2021, Nature Communications.
[5] Weili Zhao,et al. CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis , 2021, Signal Transduction and Targeted Therapy.
[6] W. Brenner,et al. Does the proteasome inhibitor bortezomib sensitize to DNA-damaging therapy in gastroenteropancreatic neuroendocrine neoplasms? – A preclinical assessment in vitro and in vivo , 2020, Neoplasia.
[7] Bryan J. Venters,et al. Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture , 2020, Nature.
[8] Andrew J. Dunford,et al. Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion. , 2019, Blood advances.
[9] Lauren C. Chong,et al. Mutational Landscape of Grey Zone Lymphoma. , 2019, Blood.
[10] Andrew J. Dunford,et al. Genomic Analyses of PMBL Reveal New Drivers and Mechanisms of Sensitivity to PD-1 Blockade. , 2019, Blood.
[11] S. Sleijfer,et al. Pan-cancer whole-genome analyses of metastatic solid tumours , 2019, Nature.
[12] K. Basso,et al. Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma. , 2019, Immunity.
[13] Lauren C. Chong,et al. Integrative genomic analysis identifies key pathogenic mechanisms in primary mediastinal large B-cell lymphoma. , 2019, Blood.
[14] Catherine L. Worth,et al. The Translational Landscape of the Human Heart , 2019, Cell.
[15] Shridar Ganesan,et al. All-FIT: Allele-Frequency-based Imputation of Tumor Purity from High-Depth Sequencing Data , 2019, bioRxiv.
[16] D. Klatzmann,et al. Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells , 2019, Front. Immunol..
[17] S. Tsunoda,et al. Age-related remodelling of oesophageal epithelia by mutated cancer drivers , 2019, Nature.
[18] S. Lowe,et al. Histone Demethylase LSD1 is required for Germinal Center formation and BCL6-driven lymphomagenesis , 2018, Nature Immunology.
[19] Alexander V Penson,et al. Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma. , 2018, Blood.
[20] Stefano Monti,et al. Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes , 2018, Nature Medicine.
[21] W. Kim. Faculty of 1000 evaluation for The 2016 revision of the World Health Organization classification of lymphoid neoplasms. , 2017 .
[22] Nicholas A. Sinnott-Armstrong,et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues , 2017, Nature Methods.
[23] K. Hogquist,et al. Directing T cell fate: How thymic antigen presenting cells coordinate thymocyte selection. , 2017, Seminars in cell & developmental biology.
[24] Qi Liu,et al. Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development , 2017, Proceedings of the National Academy of Sciences.
[25] A. Rosenwald,et al. Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma. , 2016, Blood.
[26] K. Basso,et al. Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis , 2015, Nature Medicine.
[27] Charles E. Vejnar,et al. CRISPRscan: designing highly efficient sgRNAs for CRISPR/Cas9 targeting in vivo , 2015, Nature Methods.
[28] B. Brors,et al. Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction. , 2015, Immunity.
[29] N. Matsumura,et al. IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer , 2015, British Journal of Cancer.
[30] O. Elemento,et al. Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells. , 2015, Blood.
[31] P. Farnham,et al. Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha , 2014, BMC Genomics.
[32] I. Lossos,et al. Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas , 2014, Nature Genetics.
[33] M. Calaminici,et al. Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma , 2013, Nature Genetics.
[34] O. Elemento,et al. EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. , 2013, Cancer cell.
[35] C. Riccardi,et al. Murine B Cell Development and Antibody Responses to Model Antigens Are Not Impaired in the Absence of the TNF Receptor GITR , 2012, PloS one.
[36] Mariano J. Alvarez,et al. Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesis , 2012, Proceedings of the National Academy of Sciences.
[37] Raul Rabadan,et al. Analysis of the Coding Genome of Diffuse Large B-Cell Lymphoma , 2011, Nature Genetics.
[38] P. Opolon,et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. , 2011, Cancer cell.
[39] Peggy J. Farnham,et al. ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells , 2010, Oncogene.
[40] Kearney T. W. Gunsalus,et al. The Transcription Factor REST Is Lost in Aggressive Breast Cancer , 2010, PLoS genetics.
[41] M. Walsh,et al. The ZNF217 oncogene is a candidate organizer of repressive histone modifiers , 2009, Epigenetics.
[42] K. Rajewsky,et al. Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis , 2008, The Journal of experimental medicine.
[43] S. Ziegler,et al. Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development , 2007, Nature Immunology.
[44] K. Lindblad-Toh,et al. Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals , 2005, Nature.
[45] Y. Tu,et al. Cattoretti and Riccardo Dalla-favera Tracking Cd40 Signaling during Germinal Center Development , 2022 .
[46] L. Staudt,et al. The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-κB signal transduction pathway , 2002, Oncogene.
[47] Hengbin Wang,et al. Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing , 2002, Science.
[48] I. Caramalho,et al. IFN‐α/β enhances BCR‐dependent B cell responses , 2002 .
[49] P. Hodgkin,et al. Integrating signals from IFN-gamma and IL-4 by B cells: positive and negative effects on CD40 ligand-induced proliferation, survival, and division-linked isotype switching to IgG1, IgE, and IgG2a. , 1999, Journal of immunology.
[50] C. Fonatsch,et al. Two neoplastic cell lines with unique features derived from Hodgkin's disease , 1980, International journal of cancer.
[51] Riccardo Dalla-Favera,et al. Germinal centres: role in B-cell physiology and malignancy , 2008, Nature Reviews Immunology.