Clinical applications of angiogenic growth factors and their inhibitors
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[1] J. Hartikainen,et al. Intravascular Adenovirus-Mediated VEGF-C Gene Transfer Reduces Neointima Formation in Balloon-Denuded Rabbit Aorta , 2000, Circulation.
[2] N. van Bruggen,et al. VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain. , 1999, The Journal of clinical investigation.
[3] N. Janjić,et al. VEGF(165) mediates glomerular endothelial repair. , 1999, The Journal of clinical investigation.
[4] C. Peschle,et al. KDR receptor: a key marker defining hematopoietic stem cells. , 1999, Science.
[5] P. Carmeliet,et al. Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis , 1999, Cell.
[6] Napoleone Ferrara,et al. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation , 1999, Nature Medicine.
[7] Willem Flameng,et al. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188 , 1999, Nature Medicine.
[8] Haruchika Masuda,et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization , 1999, Nature Medicine.
[9] R. Balice-Gordon,et al. Stable restoration of the sarcoglycan complex in dystrophic muscle perfused with histamine and a recombinant adeno-associated viral vector , 1999, Nature Medicine.
[10] T. Veikkola,et al. Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[11] M Aguet,et al. VEGF is required for growth and survival in neonatal mice. , 1999, Development.
[12] R. Soldi,et al. Role of αvβ3 integrin in the activation of vascular endothelial growth factor receptor‐2 , 1999, The EMBO journal.
[13] F. Diella,et al. Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. , 1999, Genes & development.
[14] H. Augustin,et al. A novel vascular endothelial growth factor encoded by Orf virus, VEGF‐E, mediates angiogenesis via signalling through VEGFR‐2 (KDR) but not VEGFR‐1 (Flt‐1) receptor tyrosine kinases , 1999, The EMBO journal.
[15] R. L. Hall,et al. Preclinical Safety Evaluation of rhuMAbVEGF, an Antiangiogenic Humanized Monoclonal Antibody , 1999, Toxicologic pathology.
[16] J. Isner,et al. Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. , 1998, Circulation.
[17] J. Isner,et al. Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results. , 1998, Journal of vascular surgery.
[18] R. Ferrell,et al. Hereditary lymphedema: evidence for linkage and genetic heterogeneity. , 1998, Human molecular genetics.
[19] M. Shibuya,et al. A Novel Type of Vascular Endothelial Growth Factor, VEGF-E (NZ-7 VEGF), Preferentially Utilizes KDR/Flk-1 Receptor and Carries a Potent Mitotic Activity without Heparin-binding Domain* , 1998, The Journal of Biological Chemistry.
[20] J. Isner,et al. Direct intramuscular injection of plasmid DNA encoding angiopoietin-1 but not angiopoietin-2 augments revascularization in the rabbit ischemic hindlimb. , 1998, Circulation.
[21] J. Pearlman,et al. VEGF administration in chronic myocardial ischemia in pigs. , 1998, Cardiovascular research.
[22] H. Blau,et al. VEGF gene delivery to muscle: potential role for vasculogenesis in adults. , 1998, Molecular cell.
[23] Thomas N. Sato,et al. Increased vascularization in mice overexpressing angiopoietin-1. , 1998, Science.
[24] R. Xavier,et al. Tumor Induction of VEGF Promoter Activity in Stromal Cells , 1998, Cell.
[25] J. Isner,et al. Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. , 1998, Circulation research.
[26] Sheela M. Waugh,et al. 2′-Fluoropyrimidine RNA-based Aptamers to the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF165) , 1998, The Journal of Biological Chemistry.
[27] J. Isner,et al. Vascular endothelial growth factor-C (VEGF-C/VEGF-2) promotes angiogenesis in the setting of tissue ischemia. , 1998, The American journal of pathology.
[28] P. Carmeliet,et al. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis , 1998, Nature.
[29] M. Dewhirst,et al. Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[30] K.,et al. Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[31] S. Rafii,et al. Evidence for circulating bone marrow-derived endothelial cells. , 1998, Blood.
[32] J. Hartikainen,et al. Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia. , 1998, Human gene therapy.
[33] J. Isner,et al. Angiogenesis and Vasculogenesis in Treatment of Cardiovascular Disease , 1998, Molecular medicine.
[34] Daniel B. Rifkin,et al. Fibroblast Growth Factor-2 (FGF-2) Induces Vascular Endothelial Growth Factor (VEGF) Expression in the Endothelial Cells of Forming Capillaries: An Autocrine Mechanism Contributing to Angiogenesis , 1998, The Journal of cell biology.
[35] David J. Anderson,et al. Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4 , 1998, Cell.
[36] E. Keshet,et al. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. , 1998, Development.
[37] H. Joensuu,et al. High pre‐treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small‐cell lung cancer , 1998, International journal of cancer.
[38] R. Crystal,et al. Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor. , 1998, Human gene therapy.
[39] R. Crystal,et al. Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion. , 1998, Journal of vascular surgery.
[40] K. Alitalo,et al. Signaling angiogenesis and lymphangiogenesis. , 1998, Current opinion in cell biology.
[41] K Walsh,et al. Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. , 1998, Circulation.
[42] Shay Soker,et al. Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor , 1998, Cell.
[43] Kenneth J. Hillan,et al. Vascular endothelial growth factor is essential for corpus luteum angiogenesis , 1998, Nature Medicine.
[44] J. Isner,et al. Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis. , 1998, Circulation.
[45] D. Weill,et al. Percutaneous endoluminal treatment of aorto-abdominal occlusive diseases , 1998 .
[46] E. Cesarman,et al. G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator , 1998, Nature.
[47] R. Hendel,et al. Results of intracoronary recombinant human vascular endothelial growth factor (rhVEGF) administration trial , 1998 .
[48] N. van Bruggen,et al. Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor. , 1998, Cancer investigation.
[49] R. Crystal,et al. Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart. , 1998, The Journal of thoracic and cardiovascular surgery.
[50] J. Isner,et al. Constitutive Expression of phVEGF 165 After Intramuscular Gene Transfer Promotes Collateral Vessel Development in Patients With Critical Limb Ischemia Clinical Investigation and Reports , 1998 .
[51] R. Jain,et al. Delivery of molecular and cellular medicine to solid tumors. , 1998, Journal of controlled release : official journal of the Controlled Release Society.
[52] M. Dewhirst,et al. Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth. , 1997, The Journal of clinical investigation.
[53] Leonard,et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. , 1997, Cancer research.
[54] M. Laakso,et al. VEGF gene transfer reduces intimal thickening via increased production of nitric oxide in carotid arteries. , 1997, Human gene therapy.
[55] K. Alitalo,et al. VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. , 1997, Developmental biology.
[56] C. Mummery,et al. Expression of ALK‐1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development , 1997, Developmental dynamics : an official publication of the American Association of Anatomists.
[57] Lois E. H. Smith,et al. Essential role of growth hormone in ischemia-induced retinal neovascularization. , 1997, Science.
[58] R. Jain,et al. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. , 1997, Science.
[59] W. Risau,et al. Mechanisms of angiogenesis , 1997, Nature.
[60] Takayuki Asahara,et al. Isolation of Putative Progenitor Endothelial Cells for Angiogenesis , 1997, Science.
[61] N. Ferrara,et al. The biology of vascular endothelial growth factor. , 1997, Endocrine reviews.
[62] O. Vinante,et al. Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma. , 1997, Journal of the National Cancer Institute.
[63] R K Jain,et al. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[64] R. Soldi,et al. The angiogenesis induced by HIV–1 Tat protein is mediated by the Flk–1/KDR receptor on vascular endothelial cells , 1996, Nature Medicine.
[65] J. Bittl,et al. Advances in coronary angioplasty. , 1996, The New England journal of medicine.
[66] J. Isner,et al. Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo. , 1996, Laboratory investigation; a journal of technical methods and pathology.
[67] K. Hillan,et al. Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy. , 1996, Cancer research.
[68] Takayuki Asahara,et al. Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb , 1996, The Lancet.
[69] A. Ullrich,et al. Flk-1 as a target for tumor growth inhibition. , 1996, Cancer research.
[70] D. Sassoon,et al. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. , 1996, Development.
[71] L. Brown,et al. VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis. , 1996, The American journal of physiology.
[72] Peipei Ping,et al. Intracoronary gene transfer of fibroblast growth factor–5 increases blood flow and contractile function in an ischemic region of the heart , 1996, Nature Medicine.
[73] Lieve Moons,et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele , 1996, Nature.
[74] Kenneth J. Hillan,et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene , 1996, Nature.
[75] D. Hinton,et al. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. , 1996, Investigative ophthalmology & visual science.
[76] A. Ullrich,et al. Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo. , 1996, Cancer research.
[77] T. Sawada,et al. Prognostic value of vascular endothelial growth factor expression in gastric carcinoma , 1996, Cancer.
[78] K. Channon,et al. Vascular gene transfer. , 1996, Heart.
[79] E S Gragoudas,et al. Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate. , 1996, Archives of ophthalmology.
[80] L. Aiello,et al. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[81] J. Isner,et al. Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. , 1995, Circulation.
[82] P. Serruys,et al. Intracoronary heparin delivery in humans. Acute feasibility and long-term results. , 1995, Circulation.
[83] J. Pearlman,et al. Magnetic resonance mapping demonstrates benefits of VEGF–induced myocardial angiogenesis , 1995, Nature Medicine.
[84] J. Isner,et al. Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery. , 1995, Circulation.
[85] K. Lehmann-Bruinsma,et al. Vascular endothelial growth factor causes endothelial proliferation after vascular injury. , 1995, Biochemical and biophysical research communications.
[86] J. Folkman. Angiogenesis in cancer, vascular, rheumatoid and other disease , 1995, Nature Medicine.
[87] L. Aiello,et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. , 1994, The New England journal of medicine.
[88] M. Raffeld,et al. Block of AIDS-Kaposi's sarcoma (KS) cell growth, angiogenesis, and lesion formation in nude mice by antisense oligonucleotide targeting basic fibroblast growth factor. A novel strategy for the therapy of KS. , 1994, The Journal of clinical investigation.
[89] J. Isner,et al. Physiological assessment of augmented vascularity induced by VEGF in ischemic rabbit hindlimb. , 1994, The American journal of physiology.
[90] W Grossman,et al. Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts. , 1994, The Journal of clinical investigation.
[91] D. Connolly,et al. Vascular endothelial growth factor as capillary permeability agent in ovarian hyperstimulation syndrome , 1994, The Lancet.
[92] E. Brogi,et al. Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. , 1994, The Journal of clinical investigation.
[93] A. Sniderman,et al. Enhanced Revascularization of the Ischemic Limb by Angiogenic Therapy , 1993, Circulation.
[94] Bing Li,et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo , 1993, Nature.
[95] F. Blodi. Pathobiology of Ocular Disease , 1983 .
[96] A. Patz,et al. Studies on retinal neovascularization. Friedenwald Lecture. , 1980, Investigative ophthalmology & visual science.
[97] J. Folkman. Tumor angiogenesis: therapeutic implications. , 1971, The New England journal of medicine.
[98] J Folkman,et al. Transplacental carcinogenesis by stilbestrol. , 1971, The New England journal of medicine.
[99] H. W. Chalkley,et al. Vasculae Reactions of Normal and Malignant Tissues in Vivo. I. Vascular Reactions of Mice to Wounds and to Normal and Neoplastic Transplants , 1945 .