Caucasian patients with type 2 diabetes mellitus have elevated levels of monocyte chemoattractant protein‐1 that are not influenced by the –2518 A→G promoter polymorphism

Aim:  To investigate the association of serum levels and the −2518 A→G promoter polymorphism of the gene for chemokine monocyte chemoattractant protein‐1 (MCP‐1), a major chemoattractant of monocytes and activated lymphocytes, with metabolic parameters as well as insulin, leptin and the cytokines tumour necrosis factor‐α (TNF‐α) and interleukin‐6 (IL‐6) in 534 Caucasian patients with type 2 diabetes mellitus.

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