Bioglass/carbonate apatite/collagen composite scaffold dissolution products promote human osteoblast differentiation.

[1]  E. Tobiasch,et al.  Effects of Silicon Compounds on Biomineralization, Osteogenesis, and Hard Tissue Formation , 2019, Pharmaceutics.

[2]  M. Mozafari,et al.  Bioactive glasses entering the mainstream. , 2018, Drug discovery today.

[3]  C. Bergwitz,et al.  Role of phosphate sensing in bone and mineral metabolism , 2018, Nature Reviews Endocrinology.

[4]  E. Fiume,et al.  Bioactive Glasses: From Parent 45S5 Composition to Scaffold-Assisted Tissue-Healing Therapies , 2018, Journal of functional biomaterials.

[5]  Julian R. Jones,et al.  Bioglass and Bioactive Glasses and Their Impact on Healthcare , 2016 .

[6]  Kai Hu,et al.  The roles of vascular endothelial growth factor in bone repair and regeneration. , 2016, Bone.

[7]  George M. Whitesides,et al.  Biomineralization Guided by Paper Templates , 2016, Scientific Reports.

[8]  B. Olsen,et al.  Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repair. , 2016, The Journal of clinical investigation.

[9]  P. Cerri,et al.  Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells , 2015, BioMed research international.

[10]  Jia Jun Chia,et al.  Phosphate uptake-independent signaling functions of the type III sodium-dependent phosphate transporter, PiT-1, in vascular smooth muscle cells. , 2015, Experimental cell research.

[11]  M. Kogo,et al.  Dysregulated Gene Expression in the Primary Osteoblasts and Osteocytes Isolated from Hypophosphatemic Hyp Mice , 2014, PloS one.

[12]  Jiang Chang,et al.  Silicate bioceramics enhanced vascularization and osteogenesis through stimulating interactions between endothelia cells and bone marrow stromal cells. , 2014, Biomaterials.

[13]  Nathaniel S. Hwang,et al.  Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling , 2014, Proceedings of the National Academy of Sciences.

[14]  Julian R. Jones,et al.  Preconditioned 70S30C bioactive glass foams promote osteogenesis in vivo. , 2013, Acta biomaterialia.

[15]  Mitchell B. Schaffler,et al.  Osteocytes: Master Orchestrators of Bone , 2013, Calcified Tissue International.

[16]  K. Phan,et al.  Comparison of a novel oxysterol molecule and rhBMP2 fusion rates in a rabbit posterolateral lumbar spine model. , 2013, The spine journal : official journal of the North American Spine Society.

[17]  R. Stephens,et al.  An integrated understanding of the physiological response to elevated extracellular phosphate , 2013, Journal of cellular physiology.

[18]  M. Reinders,et al.  Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells. , 2013, Integrative biology : quantitative biosciences from nano to macro.

[19]  A. Boccaccini,et al.  Therapeutic inorganic ions in bioactive glasses to enhance bone formation and beyond. , 2013, Biomaterials science.

[20]  G. Hunter Role of Osteopontin in Modulation of Hydroxyapatite Formation , 2013, Calcified Tissue International.

[21]  Huan Wang,et al.  L-type calcium channels play a crucial role in the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells. , 2012, Biochemical and biophysical research communications.

[22]  J. Schrooten,et al.  A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells. , 2012, Biomaterials.

[23]  Thomas A Einhorn,et al.  The biology of fracture healing. , 2011, Injury.

[24]  Aldo R Boccaccini,et al.  A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics. , 2011, Biomaterials.

[25]  L. Bonewald,et al.  The Amazing Osteocyte , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[26]  M. McKee,et al.  Loss of Skeletal Mineralization by the Simultaneous Ablation of PHOSPHO1 and Alkaline Phosphatase Function: A Unified Model of the Mechanisms of Initiation of Skeletal Calcification , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[27]  Jian Q. Feng,et al.  Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice , 2010, Proceedings of the National Academy of Sciences.

[28]  R. Takagi,et al.  FGF23 is mainly synthesized by osteocytes in the regularly distributed osteocytic lacunar canalicular system established after physiological bone remodeling. , 2009, Journal of electron microscopy.

[29]  E. Wagner,et al.  Phosphate‐Dependent Regulation of MGP in Osteoblasts: Role of ERK1/2 and Fra‐1 , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[30]  Julian R. Jones,et al.  Differentiation of fetal osteoblasts and formation of mineralized bone nodules by 45S5 Bioglass conditioned medium in the absence of osteogenic supplements. , 2009, Biomaterials.

[31]  Ming Zhang,et al.  The effect of extracellular calcium and inorganic phosphate on the growth and osteogenic differentiation of mesenchymal stem cells in vitro: implication for bone tissue engineering , 2009, Biomedical materials.

[32]  L L Hench,et al.  Bioactive glass-induced osteoblast differentiation: a noninvasive spectroscopic study. , 2008, Journal of biomedical materials research. Part A.

[33]  M. Laczka,et al.  Sol-gel bioactive glasses support both osteoblast and osteoclast formation from human bone marrow cells. , 2008, Journal of biomedical materials research. Part A.

[34]  J. Aubin,et al.  Osteoblast Autonomous Pi Regulation via Pit1 Plays a Role in Bone Mineralization , 2007, Molecular and Cellular Biology.

[35]  W. Bonfield,et al.  Human osteoblast response to silicon-substituted hydroxyapatite. , 2006, Journal of biomedical materials research. Part A.

[36]  B. Hall,et al.  Buried alive: How osteoblasts become osteocytes , 2006, Developmental dynamics : an official publication of the American Association of Anatomists.

[37]  J. Reeve,et al.  The FASEB Journal express article 10.1096/fj.05-4221fje. Published online August 25, 2005. ©2005 FASEB , 2022 .

[38]  R. Stephens,et al.  A Combined Proteome and Microarray Investigation of Inorganic Phosphate-induced Pre-osteoblast Cells*S , 2005, Molecular & Cellular Proteomics.

[39]  G. Hunter,et al.  Identification of the Type I Collagen-binding Domain of Bone Sialoprotein and Characterization of the Mechanism of Interaction* , 2005, Journal of Biological Chemistry.

[40]  M. Leite,et al.  The effect of ionic products from bioactive glass dissolution on osteoblast proliferation and collagen production. , 2004, Biomaterials.

[41]  G. Beck Inorganic phosphate as a signaling molecule in osteoblast differentiation , 2003, Journal of cellular biochemistry.

[42]  E. Moran,et al.  Inorganic phosphate regulates multiple genes during osteoblast differentiation, including Nrf2. , 2003, Experimental cell research.

[43]  K. Nakashima,et al.  Transcriptional mechanisms in osteoblast differentiation and bone formation. , 2003, Trends in genetics : TIG.

[44]  H. Anderson Matrix vesicles and calcification , 2003, Current rheumatology reports.

[45]  M. Yamauchi,et al.  Decorin modulates matrix mineralization in vitro. , 2003, Biochemical and biophysical research communications.

[46]  R. P. Thompson,et al.  Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. , 2003, Bone.

[47]  L L Hench,et al.  In vitro dissolution of melt-derived 45S5 and sol-gel derived 58S bioactive glasses. , 2002, Journal of biomedical materials research.

[48]  P. Meunier,et al.  The Degree of Mineralization of Bone Tissue Measured by Computerized Quantitative Contact Microradiography , 2002, Calcified Tissue International.

[49]  Larry L Hench,et al.  Third-Generation Biomedical Materials , 2002, Science.

[50]  J. Deng,et al.  The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation , 2002, Cell.

[51]  L L Hench,et al.  Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass 45S5 dissolution. , 2001, Journal of biomedical materials research.

[52]  J. Millán,et al.  Functional Characterization of Osteoblasts and Osteoclasts from Alkaline Phosphatase Knockout Mice , 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[53]  Larry L. Hench,et al.  Bioglass ®45S5 Stimulates Osteoblast Turnover and Enhances Bone Formation In Vitro: Implications and Applications for Bone Tissue Engineering , 2000, Calcified Tissue International.

[54]  J. Polak,et al.  Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis. , 2000, Biochemical and biophysical research communications.

[55]  E. Moran,et al.  Phosphate is a specific signal for induction of osteopontin gene expression. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[56]  H. Oonishi,et al.  Quantitative comparison of bone growth behavior in granules of Bioglass, A-W glass-ceramic, and hydroxyapatite. , 2000, Journal of biomedical materials research.

[57]  J. Klein-Nulend,et al.  MECHANOTRANSDUCTION IN BONE : ROLE OF THE LACUNOCANALICULAR NETWORK , 1999 .

[58]  Y. Takeuchi,et al.  The Primary Calcification in Bones Follows Removal of Decorin and Fusion of Collagen Fibrils , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[59]  R. Farndale,et al.  Signal pathways that transduce growth factor-stimulated mitogenesis in bone cells. , 1998, Bone.

[60]  A. Parfitt,et al.  Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[61]  Kassem,et al.  The effects of IGF‐I and IGF‐II on proliferation and differentiation of human osteoblasts and interactions with growth hormone , 1998, European journal of clinical investigation.

[62]  E. Moran,et al.  Relationship between alkaline phosphatase levels, osteopontin expression, and mineralization in differentiating MC3T3‐E1 osteoblasts , 1998, Journal of cellular biochemistry.

[63]  A. Ellinger,et al.  Effects of triiodothyronine on the morphology of cells and matrix, the localization of alkaline phosphatase, and the frequency of apoptosis in long-term cultures of MC3T3-E1 cells. , 1997, Bone.

[64]  H. Oonishi,et al.  Particulate Bioglass Compared With Hydroxyapatite as a Bone Graft Substitute , 1997, Clinical orthopaedics and related research.

[65]  Allan Bradley,et al.  Increased bone formation in osteocalcin-deficient mice , 1996, Nature.

[66]  Y. Mikuni‐Takagaki,et al.  Matrix mineralization and the differentiation of osteocyte‐like cells in culture , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[67]  P. Delmas,et al.  Osteocalcin induces chemotaxis, secretion of matrix proteins, and calcium-mediated intracellular signaling in human osteoclast-like cells , 1994, The Journal of cell biology.

[68]  J. Aubin,et al.  Cellular expression of bone‐related proteins during in vitro osteogenesis in rat bone marrow stromal cell cultures , 1994, Journal of cellular physiology.

[69]  J. Aubin,et al.  Inorganic phosphate added exogenously or released from beta-glycerophosphate initiates mineralization of osteoid nodules in vitro. , 1992, Bone and mineral.

[70]  G. Rodan,et al.  Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization , 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[71]  J B Lian,et al.  Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone. , 1989, Physiological reviews.

[72]  Howard C. Tenenbaum Levamisole and inorganic pyrophosphate inhibit beta-glycerophosphate induced mineralization of bone formed in vitro. , 1987, Bone and mineral.

[73]  K. Schwarz,et al.  Growth-promoting Effects of Silicon in Rats , 1972, Nature.

[74]  E M Carlisle,et al.  Silicon: A Possible Factor in Bone Calcification , 1970, Science.

[75]  W. Neuman,et al.  The Nature of the Mineral Phase of Bone. , 1953 .

[76]  J. Granjeiro,et al.  Matrix Metalloproteinases in Bone Resorption, Remodeling, and Repair. , 2017, Progress in molecular biology and translational science.

[77]  Jiang Chang,et al.  Osteogenesis and angiogenesis induced by porous β-CaSiO(3)/PDLGA composite scaffold via activation of AMPK/ERK1/2 and PI3K/Akt pathways. , 2013, Biomaterials.

[78]  P. A. Friedman,et al.  NHERF1 regulation of PTH-dependent bimodal Pi transport in osteoblasts. , 2013, Bone.

[79]  J. Westendorf,et al.  Regulation of gene expression in osteoblasts , 2010, BioFactors.

[80]  A. Boskey,et al.  Decorin modulates collagen matrix assembly and mineralization. , 2009, Matrix biology : journal of the International Society for Matrix Biology.

[81]  E. M. Carlisle Silicon: A requirement in bone formation independent of vitamin D1 , 2006, Calcified Tissue International.

[82]  J. Aubin Regulation of Osteoblast Formation and Function , 2004, Reviews in Endocrine and Metabolic Disorders.

[83]  C. Conover,et al.  The Role of Insulin-like Growth Factors and Binding Proteins in Bone Cell Biology , 2002 .

[84]  H. Oonishi,et al.  Comparative bone growth behavior in granules of bioceramic materials of various sizes. , 1999, Journal of biomedical materials research.

[85]  G. Stein,et al.  Apoptosis during bone‐like tissue development in vitro , 1998, Journal of cellular biochemistry.