Potential Side-Effects of CSC Systemic Approach

Central serous chorioretinopathy (CSC) is characterized by the development of serous retinal detachment typically involving the macular area [1,2]. It may be recurrent in 30-50% of cases, leading to significant visual impairment [2]. Its etiopathogenesis remains uncertain, with a variety of genetic and environmental factors possibly involved [1,2]. Among these, the role of steroids has arisen as a potential therapeutic target with the use of mineralocorticoid inhibitors like spironolactone or eplerenone [1,3].