Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma
暂无分享,去创建一个
Boris Ratnikov | Jeffrey W. Smith | A. Osterman | Z. Ronai | P. Aza-Blanc | D. Scott | B. Ratnikov | Ze'ev A. Ronai | Pedro Aza-Blanc | Andrei L. Osterman | David A. Scott | P. Aza‐Blanc | D. Scott
[1] R. Deberardinis,et al. Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis , 2007, Proceedings of the National Academy of Sciences.
[2] B. Fuchs,et al. Stressing out over survival: glutamine as an apoptotic modulator. , 2006, The Journal of surgical research.
[3] K. Lanks. End products of glucose and glutamine metabolism by L929 cells. , 1987, The Journal of biological chemistry.
[4] V. Sondak,et al. Targeted therapy in melanoma. , 2013, Clinics in dermatology.
[5] R. Dellavalle,et al. A Review of Novel Therapies for Melanoma , 2014, American Journal of Clinical Dermatology.
[6] Jiangbin Ye,et al. The GCN2‐ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation , 2010, The EMBO journal.
[7] Nicola Zamboni,et al. Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells , 2007, The Journal of cell biology.
[8] Tomer Shlomi,et al. Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia , 2013, Molecular systems biology.
[9] Christian M. Metallo,et al. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia , 2011, Nature.
[10] H. Eagle,et al. The growth response of mammalian cells in tissue culture to L-glutamine and L-glutamic acid. , 1956, The Journal of biological chemistry.
[11] D. Neuberg,et al. Long-term results of Dana-Farber Cancer Institute ALL Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1985–2000) , 2009, Leukemia.
[12] B. Crabtree,et al. Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance. , 1985, Quarterly journal of experimental physiology.
[13] Jeffrey W. Smith,et al. Functional Specialization in Proline Biosynthesis of Melanoma , 2012, PloS one.
[14] Anthony Mancuso,et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction , 2008, Proceedings of the National Academy of Sciences.
[15] V. Mootha,et al. Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation , 2012, Science.
[16] S. Kalhan,et al. The Key Role of Anaplerosis and Cataplerosis for Citric Acid Cycle Function* , 2002, Journal of Biological Chemistry.
[17] Jamey D. Young,et al. Isotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells. , 2013, Metabolic engineering.
[18] Takashi Tsukamoto,et al. Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. , 2012, Cell metabolism.
[19] M. Badet-Denisot,et al. The mechanism of glutamine-dependent amidotransferases , 1998, Cellular and Molecular Life Sciences CMLS.
[20] Dieter Jahn,et al. MetaQuant: a tool for the automatic quantification of GC/MS-based metabolome data , 2006, Bioinform..
[21] F. Young. Biochemistry , 1955, The Indian Medical Gazette.
[22] H. Krebs,et al. Isolation and metabolic characteristics of rat and chicken enterocytes. , 1979, The Biochemical journal.
[23] E. Cheng,et al. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. , 2014, Molecular cell.
[24] Jesse M. Platt,et al. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability , 2011, Proceedings of the National Academy of Sciences.
[25] Andrei L Osterman,et al. Comparative Metabolic Flux Profiling of Melanoma Cell Lines , 2011, The Journal of Biological Chemistry.
[26] J. D. Benson,et al. Single-vector inducible lentiviral RNAi system for oncology target validation , 2009, Cell cycle.
[27] H. Kornberg. Anaplerotic Sequences in Microbial Metabolism , 1965 .
[28] David S. Wishart,et al. HMDB 3.0—The Human Metabolome Database in 2013 , 2012, Nucleic Acids Res..
[29] J. Maris,et al. ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. , 2012, Cancer cell.
[30] A. Lane,et al. Targeting aspartate aminotransferase in breast cancer , 2008, Breast Cancer Research.
[31] John M. Asara,et al. Glutamine supports pancreatic cancer growth through a Kras-regulated metabolic pathway , 2013, Nature.
[32] Fabian V. Filipp,et al. Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells , 2012, Pigment cell & melanoma research.
[33] J. Tamburini,et al. Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia. , 2013, Blood.
[34] Gregory Stephanopoulos,et al. Molecular Systems Biology Peer Review Process File Oncogenic K-ras Decouples Glucose and Glutamine Metabolism to Support Cancer Cell Growth Transaction Report , 2022 .