Bone Substitute Fabrication Based on Dissolution-Precipitation Reactions

Although block- or granular-type sintered hydroxyapatite are known to show excellent tissue responses and good osteoconductivity, apatite powder elicits inflammatory response. For the fabrication of hydroxyapatite block or granules, sintering is commonly employed. However, the inorganic component of bone and tooth is not high crystalline hydroxyapatite but low crystalline B-type carbonate apatite. Unfortunately, carbonate apatite powder cannot be sintered due to its instability at high temperature. Another method to fabricate apatite block and/or granule is through phase transformation based on dissolution-precipitation reactions using a precursor phase. This reaction basically is the same as a setting and hardening reaction of calcium sulfate or plaster. In this paper, apatite block fabrication methods by phase transformation based on dissolution-precipitation reactions will be discussed, with a focus on the similarity of the setting and hardening reaction of calcium sulfate.

[1]  マシュー・イー・マーフィー,et al.  Calcium phosphate cement , 2012 .

[2]  Z. Lei,et al.  Fabrication of low crystalline B-type carbonate apatite block from low crystalline calcite block , 2010 .

[3]  K. Ishikawa,et al.  Effects of sintering temperature on physical and compositional properties of alpha-tricalcium phosphate foam. , 2010, Dental materials journal.

[4]  Shigeki Matsuya,et al.  Fabrication of low-crystallinity hydroxyapatite foam based on the setting reaction of alpha-tricalcium phosphate foam. , 2009, Journal of biomedical materials research. Part A.

[5]  K. Ishikawa,et al.  Fabrication of macroporous carbonate apatite foam by hydrothermal conversion of alpha-tricalcium phosphate in carbonate solutions. , 2008, Journal of biomedical materials research. Part A.

[6]  K. Ishikawa,et al.  Fabrication of B-type carbonate apatite blocks by the phosphorization of free-molding gypsum-calcite composite. , 2008, Dental materials journal.

[7]  K. Ishikawa,et al.  Effect of molding pressure on fabrication of low-crystalline calcite block , 2008, Journal of materials science. Materials in medicine.

[8]  K. Ishikawa,et al.  Fabrication of porous low crystalline calcite block by carbonation of calcium hydroxide compact , 2007, Journal of materials science. Materials in medicine.

[9]  S. Shintani,et al.  Effects of apatite foam combined with platelet-rich plasma on regeneration of bone defects. , 2006, Dental materials journal.

[10]  K. Koyano,et al.  Fabrication of hydroxyapatite block from gypsum block based on (NH4)2HPO4 treatment. , 2005, Dental materials journal.

[11]  J. Ricci,et al.  Bone-defect healing with calcium-sulfate particles and cement: an experimental study in rabbit. , 2004, Journal of biomedical materials research. Part B, Applied biomaterials.

[12]  D. Bradford,et al.  Calcium sulfate- and calcium phosphate-based bone substitutes. Mimicry of the mineral phase of bone. , 1999, The Orthopedic clinics of North America.

[13]  Laurence C. Chow,et al.  Properties and mechanisms of fast-setting calcium phosphate cements , 1995 .

[14]  K Asaoka,et al.  In vivo setting behaviour of fast-setting calcium phosphate cement. , 1995, Biomaterials.

[15]  宏 井上,et al.  骨充填材としてのリン酸4カルシウム・リン酸カルシウム2水和物・クエン酸硬化体の基礎的研究 , 1993 .

[16]  R Z LeGeros,et al.  Calcium phosphates in oral biology and medicine. , 1991, Monographs in oral science.

[17]  L. Napolitano.  Materials , 1984, Science.

[18]  A. Coetzee.  Regeneration of bone in the presence of calcium sulfate. , 1980, Archives of otolaryngology.

[19]  H. Aoki,et al.  [Studies on the application of apatite to dental materials. (I) --Apatite ceramics-- (author's transl)]. , 1976, Shika rikogaku zasshi. Journal of the Japan Society for Dental Apparatus and Materials.

[20]  G. App,et al.  The use of plaster of paris in treating infrabony periodontal defects in humans. , 1971, Journal of periodontology.

[21]  L. Peltier,et al.  The Use of Plaster of Paris to Fill Defects in Bone , 1957, Annals of surgery.

[22]  K. Ishikawa,et al.  Effect of temperature on crystallinity of carbonate apatite foam prepared from alpha-tricalcium phosphate by hydrothermal treatment. , 2009, Bio-medical materials and engineering.

[23]  Bhushan Lal Karihaloo,et al.  Comprehensive structural integrity , 2003 .

[24]  J. Ricci,et al.  Biological mechanisms of calcium sulfate replacement by bone , 2000 .

[25]  H. Monma,et al.  The hydration of α-tricalcium phosphate , 2000 .

[26]  T. V. van Rens.  The history of treatment using plaster of Paris. , 1987, Acta orthopaedica Belgica.

[27]  Van Rens Tj.  The history of treatment using plaster of Paris. , 1987 .

[28]  W. E. Brown,et al.  A New Calcium Phosphate, Water-setting Cement , 1986 .

[29]  H. Monma,et al.  The hydration of .ALPHA.-tricalcium phosphate. , 1976 .