Hemodynamic sensor in cardiac implantable electric devices: the endocardial accelaration technology.

There have been substantial progresses in the technology of cardiac implantable electric devices (CIEDs) during the past decades. One of the progresses is represented by the development of a hemodynamic sensor embedded at the tip of a pacing lead that measures myocardial contractility by the analysis of myocardial mechanical vibrations occurring during the cardiac cycle. This sensor, providing continuous hemodynamic monitoring, could play an important role in clinical practice because of several clinical applications in CIEDs recipients. The objectives of this work are to report how this sensor operates and to review the main findings about its clinical applications.

[1]  Jacques Victor,et al.  Programming Optimal Atrioventricular Delay in Dual Chamber Pacing Using Peak Endocardial Acceleration: Comparison with a Standard Echocardiographic Procedure , 2003, Pacing and clinical electrophysiology : PACE.

[2]  Michel Haissaguerre,et al.  Contributions of a Hemodynamic Sensor Embedded in an Atrial Lead in a Porcine Model , 2011, Journal of cardiovascular electrophysiology.

[3]  Kadir Kadhiresan,et al.  The role of implantable sensors for management of heart failure. , 2004, Studies in health technology and informatics.

[4]  Christian Pristipino,et al.  Optimization of the atrioventricular delay in sequential and biventricular pacing: physiological bases, critical review, and new purposes. , 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[5]  T. Bombardini,et al.  Peak Endocardial Acceleration Reflects Heart Contractility Also in Atrial Fibrillation , 2000, Pacing and clinical electrophysiology : PACE.

[6]  Manish S. Gupta,et al.  Rationale and design of a randomized clinical trial to assess the safety and efficacy of frequent optimization of cardiac resynchronization therapy: the Frequent Optimization Study Using the QuickOpt Method (FREEDOM) trial. , 2010, American heart journal.

[7]  L. A. Bonet,et al.  ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 , 2012, Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.

[8]  J. Deharo,et al.  DDDR Pacing Driven by Contractility Versus DDI Pacing in Vasovagal Syncope: , 2003, Pacing and clinical electrophysiology : PACE.

[9]  Michael R Gold,et al.  Optimization of Cardiac Resynchronization Therapy: Importance of Programmed Parameters , 2012, Journal of cardiovascular electrophysiology.

[10]  A. Rickards,et al.  An Implantable Intracardiac Accelerometer for Monitoring Myocardial Contractility , 1996, Pacing and clinical electrophysiology : PACE.

[11]  E. Braunwald,et al.  Studies on the first derivative of the ventricular pressure pulse in man. , 1962, The Journal of clinical investigation.

[12]  D T Mason,et al.  Usefulness and limitations of the rate of rise of intraventricular pressure (dp-dt) in the evaluation of myocardial contractility in man. , 1969, The American journal of cardiology.

[13]  Michael O Sweeney.  Peak Endocardial Acceleration Signals for Atrial Mechanical Activation , 2011, Journal of cardiovascular electrophysiology.

[14]  D. Kosinski,et al.  Pathophysiological Aspects of Neurocardiogenic Syncope: Current Concepts and New Perspectives , 1995, Pacing and clinical electrophysiology : PACE.

[15]  Guido Gaggini,et al.  Relationship between Amplitude and Timing of Heart Sounds and Endocardial Acceleration , 2009, Pacing and clinical electrophysiology : PACE.

[16]  C. Lau,et al.  Automatic Optimization of Resting and Exercise Atrioventricular Interval Using a Peak Endocardial Acceleration Sensor: Validation with Doppler Echocardiography and Direct Cardiac Output Measurements , 2000, Pacing and clinical electrophysiology : PACE.

[17]  Jeroen J. Bax,et al.  Why, how and when do we need to optimize the setting of cardiac resynchronization therapy? , 2009, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[18]  LAURENCE MANGIN,et al.  Simultaneous Analysis of Heart Rate Variability and Myocardial Contractility During Head‐Up Tilt in Patients with Vasovagal Syncope , 2001, Journal of cardiovascular electrophysiology.

[19]  Wilfried Mullens,et al.  Insights from a cardiac resynchronization optimization clinic as part of a heart failure disease management program. , 2009, Journal of the American College of Cardiology.

[20]  P Djiane,et al.  Continuous monitoring of an endocardial index of myocardial contractility during head-up tilt test. , 2000, American heart journal.

[21]  Enrico Maria Greco,et al.  Clinical Evaluation of Peak Endocardial Acceleration as a Sensor for Rate Responsive Pacing , 2003, Pacing and clinical electrophysiology : PACE.

[22]  Laura Cercenelli,et al.  Validation of a peak endocardial acceleration-based algorithm to optimize cardiac resynchronization: early clinical results , 2008, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[23]  Luigi Padeletti,et al.  A randomized pilot study of optimization of cardiac resynchronization therapy in sinus rhythm patients using a peak endocardial acceleration sensor vs. standard methods. , 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[24]  Suneet Mittal,et al.  Primary Results From the SmartDelay Determined AV Optimization: A Comparison to Other AV Delay Methods Used in Cardiac Resynchronization Therapy (SMART-AV) Trial: A Randomized Trial Comparing Empirical, Echocardiography-Guided, and Algorithmic Atrioventricular Delay Programming in Cardiac Resynchron , 2010, Circulation.

[25]  Luigi Padeletti,et al.  Discordant electrical and mechanical atrial delays affect intracavitary electrogram-based cardiac resynchronization therapy optimization. , 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[26]  E Marcelli,et al.  PEA I and PEA II based implantable haemodynamic monitor: pre clinical studies in sheep. , 2002, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[27]  J Clémenty,et al.  Validation by serial standardized testing of a new rate-responsive pacemaker sensor based on variations in myocardial contractility. , 2001, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[28]  Lotfi Senhadji,et al.  Endocardial acceleration (sonR) vs. ultrasound-derived time intervals in recipients of cardiac resynchronization therapy systems. , 2011, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[29]  Philippe Mabo,et al.  Recording of Peak Endocardial Acceleration in the Atrium , 2009, Pacing and clinical electrophysiology : PACE.

[30]  E. Soldati,et al.  Is Local Myocardial Contractility Related to Endocardial Acceleration Signals Detected by a Transvenous Pacing Lead? , 1996, Pacing and clinical electrophysiology : PACE.

[31]  L. Padeletti,et al.  Determination of the optimal atrioventricular delay in DDD pacing. Comparison between echo and peak endocardial acceleration measurements. , 1999, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.