Age-related increases in long-range connectivity in fetal functional neural connectivity networks in utero

Highlights • We examined patterns of connectivity in human fetal brain networks.• The fetal brain demonstrates cerebral-cerebellar and cortical-subcortical connectivity.• Many forms of cerebral connectivity are present by the third trimester.• Default mode network connections were evident in fetuses older than 35 weeks.• Long-range functional connectivity is more prominent in older fetuses.

[1]  Evan M. Gordon,et al.  Developmental cognitive neuroscience , 2011, Developmental Cognitive Neuroscience.

[2]  A. Snyder,et al.  Longitudinal analysis of neural network development in preterm infants. , 2010, Cerebral cortex.

[3]  Peter Fransson,et al.  Spontaneous Brain Activity in the Newborn Brain During Natural Sleep—An fMRI Study in Infants Born at Full Term , 2009, Pediatric Research.

[4]  N. Jovanov-Milošević,et al.  The development of cerebral connections during the first 20-45 weeks' gestation. , 2006, Seminars in fetal & neonatal medicine.

[5]  Karl J. Friston Functional integration and inference in the brain , 2002, Progress in Neurobiology.

[6]  Dinggang Shen,et al.  Evidence on the emergence of the brain's default network from 2-week-old to 2-year-old healthy pediatric subjects , 2009, Proceedings of the National Academy of Sciences.

[7]  O. Sporns,et al.  White matter maturation reshapes structural connectivity in the late developing human brain , 2010, Proceedings of the National Academy of Sciences.

[8]  Biyu J. He,et al.  Loss of Resting Interhemispheric Functional Connectivity after Complete Section of the Corpus Callosum , 2008, The Journal of Neuroscience.

[9]  Christos Davatzikos,et al.  Heterogeneous impact of motion on fundamental patterns of developmental changes in functional connectivity during youth , 2013, NeuroImage.

[10]  D. Prayer,et al.  Watching the fetal brain at ‘rest’ , 2012, International Journal of Developmental Neuroscience.

[11]  Todd Jackson Relationships Between Perceived Close Social Support and Health Practices Within Community Samples of American Women and Men , 2006, The Journal of psychology.

[12]  Colin Studholme,et al.  Cross-Hemispheric Functional Connectivity in the Human Fetal Brain , 2013, Science Translational Medicine.

[13]  Moriah E. Thomason,et al.  Intrinsic Functional Brain Architecture Derived from Graph Theoretical Analysis in the Human Fetus , 2014, PloS one.

[14]  Peter Fransson,et al.  Resting-state networks in the infant brain , 2007, Proceedings of the National Academy of Sciences.

[15]  Jonathan D. Power,et al.  The Development of Human Functional Brain Networks , 2010, Neuron.

[16]  Maurizio Corbetta,et al.  The human brain is intrinsically organized into dynamic, anticorrelated functional networks. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[17]  M. Sur,et al.  Plasticity and specificity of cortical processing networks , 2006, Trends in Neurosciences.

[18]  Thomas T. Liu,et al.  A component based noise correction method (CompCor) for BOLD and perfusion based fMRI , 2007, NeuroImage.

[19]  Dost Öngür,et al.  Anticorrelations in resting state networks without global signal regression , 2012, NeuroImage.

[20]  Justin L. Vincent,et al.  Distinct brain networks for adaptive and stable task control in humans , 2007, Proceedings of the National Academy of Sciences.

[21]  Arno Villringer,et al.  Identifying the perfusion deficit in acute stroke with resting‐state functional magnetic resonance imaging , 2013, Annals of neurology.

[22]  Susan L. Whitfield-Gabrieli,et al.  Conn: A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks , 2012, Brain Connect..

[23]  Emi Takahashi,et al.  Emerging cerebral connectivity in the human fetal brain: an MR tractography study. , 2012, Cerebral cortex.

[24]  D. Prayer,et al.  Magnetic resonance methods in fetal neurology. , 2012, Seminars in fetal & neonatal medicine.

[25]  Matthias Bethge,et al.  Natural Image Coding in V1: How Much Use Is Orientation Selectivity? , 2008, PLoS Comput. Biol..

[26]  Justin L. Vincent,et al.  Intrinsic functional architecture in the anaesthetized monkey brain , 2007, Nature.

[27]  Jonathan D. Power,et al.  Functional Brain Networks Develop from a “Local to Distributed” Organization , 2009, PLoS Comput. Biol..

[28]  Kaustubh Supekar,et al.  Development of Large-Scale Functional Brain Networks in Children , 2009, NeuroImage.

[29]  M. Greicius,et al.  Resting-state functional connectivity reflects structural connectivity in the default mode network. , 2009, Cerebral cortex.

[30]  Moriah E. Thomason,et al.  Functional plasticity before the cradle: A review of neural functional imaging in the human fetus , 2013, Neuroscience & Biobehavioral Reviews.

[31]  Gregor Kasprian,et al.  In utero tractography of fetal white matter development , 2008, NeuroImage.

[32]  Mark W. Woolrich,et al.  Advances in functional and structural MR image analysis and implementation as FSL , 2004, NeuroImage.

[33]  Daniel Rueckert,et al.  Construction of a consistent high-definition spatio-temporal atlas of the developing brain using adaptive kernel regression , 2012, NeuroImage.

[34]  Richard M. Leahy,et al.  BrainSuite: An Automated Cortical Surface Identification Tool , 2000, MICCAI.

[35]  Catie Chang,et al.  Effects of model-based physiological noise correction on default mode network anti-correlations and correlations , 2009, NeuroImage.

[36]  V. Calhoun,et al.  Changes in the interaction of resting‐state neural networks from adolescence to adulthood , 2009, Human brain mapping.

[37]  Rupert Lanzenberger,et al.  Correlations and anticorrelations in resting-state functional connectivity MRI: A quantitative comparison of preprocessing strategies , 2009, NeuroImage.

[38]  Ivica Kostović,et al.  Subplate zone of the human brain: historical perspective and new concepts. , 2008, Collegium antropologicum.

[39]  C. Shatz,et al.  Synaptic Activity and the Construction of Cortical Circuits , 1996, Science.

[40]  Abraham Z. Snyder,et al.  Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion , 2012, NeuroImage.

[41]  D. Margulies,et al.  Development of anterior cingulate functional connectivity from late childhood to early adulthood. , 2009, Cerebral cortex.

[42]  S. Petersen,et al.  Development of distinct control networks through segregation and integration , 2007, Proceedings of the National Academy of Sciences.

[43]  Mert R. Sabuncu,et al.  The influence of head motion on intrinsic functional connectivity MRI , 2012, NeuroImage.

[44]  F. Turkheimer,et al.  Emergence of resting state networks in the preterm human brain , 2010, Proceedings of the National Academy of Sciences.

[45]  Kevin Murphy,et al.  The impact of global signal regression on resting state correlations: Are anti-correlated networks introduced? , 2009, NeuroImage.