Digital breast tomosynthesis from concept to clinical care.

OBJECTIVE The purpose of this article is to describe the development of digital breast tomosynthesis (DBT) and to describe its advantages over 2D mammography for breast cancer screening. CONCLUSION Mammographic screening has dramatically reduced breast cancer deaths, but it does not depict all cancer early enough to result in a cure. In addition, because of the recall rates associated with mammography, efforts are underway to reduce access to screening. Use of DBT improves sensitivity and specificity, and there is no longer a need to obtain full-exposure 2D mammograms. DBT will replace standard 2D mammography for breast cancer screening.

[1]  S. Rose,et al.  Implementation of breast tomosynthesis in a routine screening practice: an observational study. , 2013, AJR. American journal of roentgenology.

[2]  H. Nelson,et al.  Screening for Breast Cancer: An Update for the U.S. Preventive Services Task Force , 2009, Annals of Internal Medicine.

[3]  Jean B. Cormack,et al.  Combined screening with ultrasound and mammography vs mammography alone in women at elevated risk of breast cancer. , 2008, JAMA.

[4]  R A Schmidt,et al.  Automated detection of microcalcification clusters for digital breast tomosynthesis using projection data only: a preliminary study. , 2008, Medical physics.

[5]  E. Miller,et al.  Combined optical and X-ray tomosynthesis breast imaging. , 2011, Radiology.

[6]  E. Miller,et al.  An infinite number of laminagrams from a finite number of radiographs. , 1971, Radiology.

[7]  D. Kopans Point: The New England Journal of Medicine article suggesting overdiagnosis from mammography screening is scientifically incorrect and should be withdrawn. , 2013, Journal of the American College of Radiology : JACR.

[8]  L. Tabár,et al.  Quantifying the potential problem of overdiagnosis of ductal carcinoma in situ in breast cancer screening. , 2003, European journal of cancer.

[9]  C. Waldherr,et al.  Value of one-view breast tomosynthesis versus two-view mammography in diagnostic workup of women with clinical signs and symptoms and in women recalled from screening. , 2013, AJR. American journal of roentgenology.

[10]  Tor D Tosteson,et al.  Digital breast tomosynthesis: initial experience in 98 women with abnormal digital screening mammography. , 2007, AJR. American journal of roentgenology.

[11]  Sara Gavenonis,et al.  Calcifications in the Breast and Digital Breast Tomosynthesis , 2011, The breast journal.

[12]  L. Tabár,et al.  Swedish two-county trial: impact of mammographic screening on breast cancer mortality during 3 decades. , 2011, Radiology.

[13]  A. Verbeek,et al.  Increasingly strong reduction in breast cancer mortality due to screening , 2011, British Journal of Cancer.

[14]  R. Edward Hendrick,et al.  Performance comparison of single-view digital breast tomosynthesis plus single-view digital mammography with two-view digital mammography , 2013, European Radiology.

[15]  L. Tabár,et al.  Long‐term incidence of breast cancer by trial arm in one county of the Swedish Two‐County Trial of mammographic screening , 2012, Cancer.

[16]  Eugenio Paci,et al.  Overdiagnosis in Mammographic Screening for Breast Cancer in Europe: A Literature Review , 2012, Journal of medical screening.

[17]  A. Bleyer,et al.  Effect of three decades of screening mammography on breast-cancer incidence. , 2012, The New England journal of medicine.

[18]  S. Duffy,et al.  Overdiagnosis in Screening: Is the Increase in Breast Cancer Incidence Rates a Cause for Concern ? , 2004 .

[19]  David Gur,et al.  Detection and classification of calcifications on digital breast tomosynthesis and 2D digital mammography: a comparison. , 2011, AJR. American journal of roentgenology.

[20]  Andriy I. Bandos,et al.  Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population-based screening program. , 2013, Radiology.

[21]  S. Ciatto,et al.  Integration of 3D digital mammography with tomosynthesis for population breast-cancer screening (STORM): a prospective comparison study. , 2013, The Lancet. Oncology.

[22]  B. W. Perry,et al.  Predicting the risk of cancer at the time of breast biopsy. Variation in the benign to malignant ratio. , 1982, The American surgeon.

[23]  Håkan Jonsson,et al.  Reduction in Breast Cancer Mortality from Organized Service Screening with Mammography: 1. Further Confirmation with Extended Data , 2006, Cancer Epidemiology Biomarkers & Prevention.

[24]  C. D'Orsi,et al.  Diagnostic Performance of Digital Versus Film Mammography for Breast-Cancer Screening , 2005, The New England journal of medicine.

[25]  D. Kopans JUST THE FACTS: MAMMOGRAPHY SAVES LIVES WITH LITTLE IF ANY RADIATION RISK TO THE MATURE BREAST , 2011, Health physics.

[27]  J. Hendriks,et al.  Initiation of population-based mammography screening in Dutch municipalities and effect on breast-cancer mortality: a systematic review , 2003, The Lancet.

[28]  Håkan Jonsson,et al.  Effectiveness of population‐based service screening with mammography for women ages 40 to 49 years , 2011, Cancer.

[29]  L. Tabár,et al.  Overdiagnosis and overtreatment of breast cancer: Estimates of overdiagnosis from two trials of mammographic screening for breast cancer , 2005, Breast Cancer Research.

[30]  S. Duffy,et al.  Mammographic screening and "overdiagnosis". , 2011, Radiology.

[31]  I. Vejborg,et al.  Overdiagnosis in screening mammography in Denmark: population based cohort study , 2013, BMJ : British Medical Journal.

[32]  David Gur,et al.  Time to diagnosis and performance levels during repeat interpretations of digital breast tomosynthesis: preliminary observations. , 2010, Academic radiology.

[33]  D. Kopans Beyond randomized controlled trials , 2002, Cancer.

[34]  E. Halpern,et al.  Assessing radiologist performance using combined digital mammography and breast tomosynthesis compared with digital mammography alone: results of a multicenter, multireader trial. , 2013, Radiology.

[35]  C A Kelsey,et al.  Benefits versus risks from mammography: A critical reasessment , 1996, Cancer.

[36]  D. Kopans,et al.  Tomographic mammography using a limited number of low-dose cone-beam projection images. , 2003, Medical physics.

[37]  L T Niklason,et al.  Digital breast imaging: tomosynthesis and digital subtraction mammography. , 1998, Breast disease.

[38]  Liem T. Bui-Mansfield Breast Imaging, 3rd ed. , 2008 .

[39]  David Gur,et al.  Digital breast tomosynthesis versus supplemental diagnostic mammographic views for evaluation of noncalcified breast lesions. , 2013, Radiology.

[40]  L. Tabár,et al.  Beyond randomized controlled trials , 2001, Cancer.

[41]  John M Lewin,et al.  Dual-energy contrast-enhanced digital subtraction mammography: feasibility. , 2003, Radiology.

[42]  A. Coldman,et al.  Breast cancer mortality after screening mammography in British Columbia women , 2006, International journal of cancer.

[43]  D. Kopans,et al.  Digital tomosynthesis in breast imaging. , 1997, Radiology.

[44]  P. Gøtzsche Time to stop mammography screening? , 2011, Canadian Medical Association Journal.

[45]  Tao Wu,et al.  A comparison of reconstruction algorithms for breast tomosynthesis. , 2004, Medical physics.

[46]  Martin J Yaffe,et al.  Contrast-enhanced digital mammography: initial clinical experience. , 2003, Radiology.

[47]  L. Tabár,et al.  The impact of organized mammography service screening on breast carcinoma mortality in seven Swedish counties , 2002, Cancer.

[48]  H P DOUB THE RADIOLOGICAL SOCIETY OF NORTH AMERICA; FIFTY YEARS OF PROGRESS. , 1964, Radiology.

[49]  Ellen Warner,et al.  Surveillance of BRCA1 and BRCA2 mutation carriers with magnetic resonance imaging, ultrasound, mammography, and clinical breast examination , 2004, JAMA.

[50]  J. Otten,et al.  Mammography Screening and Risk of Breast Cancer Death: A Population-Based Case–Control Study , 2011, Cancer Epidemiology, Biomarkers & Prevention.

[51]  Ingvar Andersson,et al.  Rate of over-diagnosis of breast cancer 15 years after end of Malmö mammographic screening trial: follow-up study , 2006, BMJ : British Medical Journal.

[52]  S. Feig,et al.  Screening for cancer: when is it valid?--Lessons from the mammography experience. , 2003, Radiology.

[53]  D B Kopans,et al.  Screening for breast cancer and mortality reduction among women 40–49 years of age , 1994, Cancer.

[54]  Rhian Gabe,et al.  The randomized trials of breast cancer screening: what have we learned? , 2004, Radiologic clinics of North America.