论文信息 - Synthesis of o‐(Dimethylamino)aryl Ketones, Acridones, Acridinium Salts, and 1H‐Indazoles by the Reaction of Hydrazones and Arynes.

Synthesis of o‐(Dimethylamino)aryl Ketones, Acridones, Acridinium Salts, and 1H‐Indazoles by the Reaction of Hydrazones and Arynes.

The formation of (dimethylamino)aryl ketones proceeds via a benzyne-induced cyclization towards an intermediary dihydroindazole followed by ring-opening and hydrolysis of the resulting o-aminoaryl ketimine.

R. Larock | A. Dubrovskiy

[1] R. Larock,et al. Synthesis of o-(dimethylamino)aryl ketones, acridones, acridinium salts, and 1H-indazoles by the reaction of hydrazones and arynes. , 2012, The Journal of organic chemistry.