Polymorphisms of the matrix metalloproteinase 9 gene and abdominal aortic aneurysm

Increased matrix metalloproteinase (MMP) 9 activity has been implicated in the formation of abdominal aortic aneurysm (AAA). The aim was to explore the association between potentially functional variants of the MMP‐9 gene and AAA.

[1]  Henrik Madsen,et al.  Introduction to Generalized Linear Models , 2012 .

[2]  Paula Clancy,et al.  Association Between Osteopontin and Human Abdominal Aortic Aneurysm , 2007, Arteriosclerosis, thrombosis, and vascular biology.

[3]  Bronwyn A. Kingwell,et al.  Matrix Metalloproteinase-9 Genotype Influences Large Artery Stiffness Through Effects on Aortic Gene and Protein Expression , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[4]  S. Shapiro,et al.  Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. , 2000, The Journal of clinical investigation.

[5]  K. Angquist,et al.  Activity of matrix metalloproteinase-2 and -9 in abdominal aortic aneurysms. Relation to size and rupture. , 2000, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[6]  Kim W. Carter,et al.  SimHap: A comprehensive modelling framework and a simulation-based approach to haplotypic analysis of population-based data , 2006 .

[7]  J. Lindholt,et al.  The plasma level of matrix metalloproteinase 9 may predict the natural history of small abdominal aortic aneurysms. A preliminary study. , 2000, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[8]  Gregory T. Jones,et al.  Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysm. , 2003, Journal of vascular surgery.

[9]  G. Seabrook,et al.  Response of plasma matrix metalloproteinase-9 to conventional abdominal aortic aneurysm repair or endovascular exclusion: implications for endoleak. , 2002, Journal of vascular surgery.

[10]  P. Delvenne,et al.  Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms. , 1996, Journal of vascular surgery.

[11]  W. Pearce,et al.  Size matters: the relationship between MMP-9 expression and aortic diameter. , 1997, Circulation.

[12]  K. Jamrozik,et al.  Infrarenal Aortic Diameter Predicts All-Cause Mortality , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[13]  Leon Flicker,et al.  Cohort Profile: The Health In Men Study (HIMS). , 2009, International journal of epidemiology.

[14]  Konrad Jamrozik,et al.  Population based randomised controlled trial on impact of screening on mortality from abdominal aortic aneurysm , 2004, BMJ : British Medical Journal.

[15]  L. Excoffier,et al.  Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. , 1995, Molecular biology and evolution.

[16]  S. Humphries,et al.  Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis. , 2008, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[17]  Ross Ihaka,et al.  Gentleman R: R: A language for data analysis and graphics , 1996 .

[18]  D. Hovsepian,et al.  Elevated plasma levels of matrix metalloproteinase-9 in patients with abdominal aortic aneurysms: a circulating marker of degenerative aneurysm disease. , 2000, Journal of vascular and interventional radiology : JVIR.

[19]  K. Jamrozik,et al.  Screening for abdominal aortic aneurysm: lessons from a population‐based study , 2000, The Medical journal of Australia.

[20]  W. Pearce,et al.  Increased plasma levels of metalloproteinase-9 are associated with abdominal aortic aneurysms. , 1999, Journal of vascular surgery.

[21]  J. Powell,et al.  Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[22]  E. Choke,et al.  Elevated plasma MMP1 and MMP9 are associated with abdominal aortic aneurysm rupture. , 2008, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[23]  K. Goddard,et al.  Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms. , 2005, Journal of Vascular Surgery.

[24]  G. Ailawadi,et al.  A nonintrinsic regional basis for increased infrarenal aortic MMP-9 expression and activity. , 2003, Journal of vascular surgery.

[25]  Eric R. Ziegel,et al.  An Introduction to Generalized Linear Models , 2002, Technometrics.

[26]  Timothy C Greiner,et al.  Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. , 2002, The Journal of clinical investigation.

[27]  G. Sangiorgi,et al.  Plasma Levels of Metalloproteinases-3 and -9 as Markers of Successful Abdominal Aortic Aneurysm Exclusion After Endovascular Graft Treatment , 2001, Circulation.

[28]  K. Jamrozik,et al.  Negative association between infra-renal aortic diameter and glycaemia: the Health in Men Study. , 2007, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[29]  P. Kitslaar,et al.  Systemic dilation diathesis in patients with abdominal aortic aneurysms: a role for matrix metalloproteinase-9? , 2005, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[30]  M. Thompson,et al.  Matrix Metalloproteinase-8 and -9 Are Increased at the Site of Abdominal Aortic Aneurysm Rupture , 2005, Circulation.

[31]  K. Jamrozik,et al.  C-Reactive Protein Levels and the Expansion of Screen-Detected Abdominal Aortic Aneurysms in Men , 2004, Circulation.

[32]  A. Hamsten,et al.  Genotype–phenotype relationships in an investigation of the role of proteases in abdominal aortic aneurysm expansion , 2005, The British journal of surgery.

[33]  A. Evans,et al.  Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis. , 1999, Circulation.