Constitutive and Ligand-Induced TCR

[1]  C. Geisler,et al.  TCR trafficking in resting and stimulated T cells. , 2004, Critical reviews in immunology.

[2]  P. S. Andersen,et al.  TCR Comodulation of Nonengaged TCR Takes Place by a Protein Kinase C and CD3γ Di-Leucine-Based Motif-Dependent Mechanism 1 , 2003, The Journal of Immunology.

[3]  Martin Wiedmann,et al.  The Organizing Principle in the Formation of the T Cell Receptor-CD3 Complex , 2002, Cell.

[4]  M. Naramura,et al.  c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation , 2002, Nature Immunology.

[5]  T. Karpova,et al.  Regulation of Constitutive TCR Internalization by the ζ-Chain , 2002, The Journal of Immunology.

[6]  B. Gastman,et al.  Granzyme B-mediated Degradation of T-Cell Receptor Chain1 , 2002 .

[7]  P. S. Andersen,et al.  The CD3γ Leucine-Based Receptor-Sorting Motif Is Required for Efficient Ligand-Mediated TCR Down-Regulation1 , 2002, The Journal of Immunology.

[8]  C. Geisler,et al.  Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling. , 2002, European journal of immunology.

[9]  P. S. Andersen,et al.  T‐Cell Receptor Downregulation by Ceramide‐Induced Caspase Activation and Cleavage of the ζ Chain , 2001, Scandinavian journal of immunology.

[10]  B. Goldstein,et al.  Calculations show substantial serial engagement of T cell receptors. , 2001, Biophysical journal.

[11]  D. Wiest,et al.  On the dynamics of TCR:CD3 complex cell surface expression and downmodulation. , 2000, Immunity.

[12]  P. Schwartzberg,et al.  Deficiency of PTEN in Jurkat T Cells Causes Constitutive Localization of Itk to the Plasma Membrane and Hyperresponsiveness to CD3 Stimulation , 2000, Molecular and Cellular Biology.

[13]  Rubin,et al.  Dissection of the Role of CD3γ Chains in Profound but Reversible T‐Cell Receptor Down‐regulation , 2000, Scandinavian journal of immunology.

[14]  L. Hicke,et al.  Monoubiquitin carries a novel internalization signal that is appended to activated receptors , 2000, The EMBO journal.

[15]  B. Alarcón,et al.  Internalization and intracellular fate of TCR-CD3 complexes. , 2000, Critical reviews in immunology.

[16]  B. Alarcón,et al.  Receptor Engagement Transiently Diverts the T Cell Receptor Heterodimer from a Constitutive Degradation Pathway* , 1999, The Journal of Biological Chemistry.

[17]  F. Martinon,et al.  Degradation of ZAP-70 following antigenic stimulation in human T lymphocytes: role of calpain proteolytic pathway. , 1999, Journal of immunology.

[18]  C. Geisler,et al.  TCRζ is transported to and retained in the Golgi apparatus independently of other TCR chains: implications for TCR assembly , 1999, European journal of immunology.

[19]  J. C. Pratt,et al.  The Extracellular Signal-regulated Kinase Pathway Is Required for Activation-induced Cell Death of T Cells* , 1999, The Journal of Biological Chemistry.

[20]  A. Trautmann,et al.  Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor Signaling , 1999 .

[21]  T. Whiteside,et al.  Caspase-mediated Degradation of T-Cell Receptor z-Chain1 , 1999 .

[22]  R. Germain,et al.  Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: relationship to the quality of individual TCR signaling events. , 1999, Journal of immunology.

[23]  C. Geisler,et al.  T Cell Receptor ζ Allows Stable Expression of Receptors Containing the CD3γ Leucine-based Receptor-sorting Motif* , 1998, The Journal of Biological Chemistry.

[24]  C. Geisler,et al.  The Phosphorylation State of CD3γ Influences T Cell Responsiveness and Controls T Cell Receptor Cycling* , 1998, The Journal of Biological Chemistry.

[25]  C. Geisler,et al.  Two distinct pathways exist for down-regulation of the TCR. , 1998, Journal of immunology.

[26]  A. Dautry‐Varsat,et al.  Differential cytosolic tail dependence and intracellular fate of T cell receptors internalized upon activation with superantigen or phorbol ester , 1998, Research in immunology.

[27]  J. Ashwell,et al.  Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation. , 1997, Immunity.

[28]  A. Lanzavecchia,et al.  Degradation of  T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation , 1997, The Journal of experimental medicine.

[29]  J. Gorvel,et al.  Tyrosine and serine protein kinase activities associated with ligand-induced internalized TCR/CD3 complexes. , 1997, Journal of immunology.

[30]  M. Jackson,et al.  Requirements for Peptide-induced T Cell Receptor Downregulation on Naive CD8+ T Cells , 1997, The Journal of experimental medicine.

[31]  小野暁.  Rapid turnover of the CD3ζ chain independent of the TCR-CD3 complex in normal T cells(正常T細胞におけるTCR-CD3複合体から独立したCD3ζ鎖の早い代謝回転) , 1997 .

[32]  A. Weissman,et al.  T Cell Antigen Receptor Ubiquitination Is a Consequence of Receptor-mediated Tyrosine Kinase Activation (*) , 1996, The Journal of Biological Chemistry.

[33]  C. Geisler,et al.  Role of CD3 /in T Cell Receptor Assembly , 1996 .

[34]  Y. Asano,et al.  Physical dissociation of the TCR-CD3 complex accompanies receptor ligation , 1995, The Journal of experimental medicine.

[35]  A. Dautry‐Varsat,et al.  The Staphylococcus aureus Enterotoxin B Superantigen Induces Specific T Cell Receptor Down-regulation by Increasing Its Internalization (*) , 1995, The Journal of Biological Chemistry.

[36]  A. Lanzavecchia,et al.  Serial triggering of many T-cell receptors by a few peptide–MHC complexes , 1995, Nature.

[37]  H. Teh,et al.  The protein tyrosine kinase p56lck regulates TCR expression and T cell selection. , 1995, International immunology.

[38]  P. Krammer,et al.  Autocrine T-cell suicide mediated by APO-1/(Fas/CD95) , 1995, Nature.

[39]  C. Geisler,et al.  Structure of the T cell receptor in a TiαVβ2,αVβ8‐positive T cell line , 1994 .

[40]  D. Lauffenburger,et al.  Receptors: Models for Binding, Trafficking, and Signaling , 1993 .

[41]  V. Fried,et al.  Activation-induced ubiquitination of the T cell antigen receptor. , 1992, Science.

[42]  A. Wakeham,et al.  Profound block in thymocyte development in mice lacking p56lck , 1992, Nature.

[43]  B. Alarcón,et al.  Assembly and function of the T cell antigen receptor. Requirement of either the lysine or arginine residues in the transmembrane region of the alpha chain. , 1990, The Journal of biological chemistry.

[44]  J. Lippincott-Schwartz,et al.  The T cell antigen receptor: insights into organelle biology. , 1990, Annual review of cell biology.

[45]  J. Lippincott-Schwartz,et al.  Subunit interactions within the T-cell antigen receptor: clues from the study of partial complexes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[46]  C. Geisler,et al.  Characterization and Expression of the Human T Cell Receptor‐T3 Complex by Monoclonal Antibody F101.01 , 1988, Scandinavian journal of immunology.

[47]  J. Hansen,et al.  Endocytosis and degradation of murine anti-human CD3 monoclonal antibodies by normal and malignant T-lymphocytes. , 1988, Cancer research.

[48]  J. Lippincott-Schwartz,et al.  Failure to synthesize the T Cell CD3-ζ chain: Structure and function of a partial T cell receptor complex , 1988, Cell.

[49]  H Clevers,et al.  The T cell receptor/CD3 complex: a dynamic protein ensemble. , 1988, Annual review of immunology.

[50]  R. Klausner,et al.  Internalization and cycling of the T cell antigen receptor. Role of protein kinase C. , 1987, The Journal of biological chemistry.

[51]  R D Klausner,et al.  Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[52]  M. Krangel.  Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation , 1987, The Journal of experimental medicine.

[53]  R. Amson,et al.  Internalization of human T lymphocyte receptors , 1987, European journal of immunology.

[54]  J. Lamb,et al.  Tolerance of T-cell clones is associated with membrane antigen changes , 1983, Nature.

[55]  J. Lamb,et al.  Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin , 1983, The Journal of experimental medicine.

[56]  E. Reinherz,et al.  Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex , 1982, Cell.