Synthesis of MOFs: a personal view on rationalisation, application and exploration.

This perspective highlights some studies and insights in the synthesis of metal-organic frameworks (MOFs) in a brief and comprehensive manner. The understanding of the synthesis procedures investigated by in and ex situ methods is of special interest since knowledge on the nucleation and crystallisation mechanism will ideally lead to an improved control over product formation. The prospective developments associated with the manufacturing of such materials (or devices consisting thereof) are discussed as well. A major challenge is the adjustment of the synthesis conditions to yield quantities suitable for real life applications. Last but not least, vast opportunities are yet to be explored involving the synthesis of both known and novel compounds. Thus the crucial points involving the synthesis of MOFs summarized in this perspective are rationalisation, application and exploration. For each subtopic we have also attempted to anticipate future challenges and developments.