Extrapolation of Toxicological and Pharmacological Data from Animals to Humans

[1]  A. Grollman PHYSIOLOGICAL VARIATIONS IN THE CARDIAC OUTPUT OF MAN: VI. The Value of the Cardiac Output of the Normal Individual in the Basal, Resting Condition , 1929 .

[2]  Jerrold H. Zar,et al.  Calculation and Miscalculation of the Allometric Equation as a Model in Biological Data , 1968 .

[3]  M Rowland,et al.  Physiologic pharmacokinetic models and interanimal species scaling. , 1985, Pharmacology & therapeutics.

[4]  I W Davidson,et al.  Biological basis for extrapolation across mammalian species. , 1986, Regulatory toxicology and pharmacology : RTP.

[5]  B. Shnider Early human trials with anticancer agents. Dosage schedules and routes of administration. , 1962, Journal of chronic diseases.

[6]  J. Crawford,et al.  Simplification of drug dosage calculation by application of the surface area principle. , 1950, Pediatrics.

[7]  L. J. West,et al.  Lysergic Acid Diethylamide: Its Effects on a Male Asiatic Elephant. , 1962, Science.

[8]  T. Terasaki,et al.  Physiologically based pharmacokinetic model for cefazolin in rabbits and its preliminary extrapolation to man. , 1985, Drug metabolism and disposition: the biological fate of chemicals.

[9]  M. Kleiber Body size and metabolism , 1932 .

[10]  K. Spells,et al.  Comparative studies in lung mechanics based on a survey of literature data. , 1969, Respiration physiology.

[11]  J. Mordenti,et al.  Man versus beast: pharmacokinetic scaling in mammals. , 1986, Journal of pharmaceutical sciences.

[12]  Operational time and theory of biological similarities. , 1968, Journal of theoretical biology.

[13]  W. Calder,et al.  Scaling of physiological processes in homeothermic animals. , 1981, Annual review of physiology.

[14]  M. Kleiber Metabolic turnover rate: a physiological meaning of the metabolic rate per unit body weight. , 1975, Journal of theoretical biology.

[15]  A. Heusner Energy metabolism and body size. II. Dimensional analysis and energetic non-similarity. , 1982, Respiration physiology.

[16]  D. Rall,et al.  The evaluation of anticancer drugs in dogs and monkeys for the prediction of qualitative toxicities in man , 1970, Clinical pharmacology and therapeutics.

[17]  H. Feldman,et al.  The 3/4 mass exponent for energy metabolism is not a statistical artifact. , 1983, Respiration physiology.

[18]  E. Muntwyler,et al.  Plasma Volume, "Available (Thiocyanate) Volume" and Total Circulating Plasma Proteins in Normal Adults. , 1945, Annals of surgery.

[19]  J. Crawford,et al.  Homeostatic limits to safe parenteral fluid therapy. , 1953, The New England journal of medicine.

[20]  S. Glantz,et al.  Age‐Related Changes in Ouabain Pharmacology Ouabain Exhibits a Different Volume of Distribution in Adult and Young Dogs , 1976, Circulation research.

[21]  E. Adolph,et al.  Quantitative Relations in the Physiological Constitutions of Mammals. , 1949, Science.

[22]  H. Boxenbaum Evolutionary biology, animal behavior, fourth-dimensional space, and the raison d'etre of drug metabolism and pharmacokinetics. , 1983, Drug metabolism reviews.

[23]  J. Wagner,et al.  Blood Levels of Drug at the Equilibrium State after Multiple Dosing , 1965, Nature.

[24]  D G Hoel,et al.  Estimation of risks of irreversible, delayed toxicity. , 1975, Journal of toxicology and environmental health.

[25]  R. Lacy,et al.  Basal metabolic rates in mammals: taxonomic differences in the allometry of BMR and body mass. , 1985, Comparative biochemistry and physiology. A, Comparative physiology.

[26]  H Boxenbaum,et al.  Interspecies pharmacokinetic scaling and the evolutionary-comparative paradigm. , 1984, Drug metabolism reviews.

[27]  Interspecific scaling of toxicity data: a question of interpretation. , 1989, Risk analysis : an official publication of the Society for Risk Analysis.

[28]  N Mantel,et al.  Estimating "safe" levels, a hazardous undertaking. , 1975, Cancer research.

[29]  M. Kleiber Prefatory chapter: an old professor of animal husbandry ruminates. , 1967, Annual review of physiology.

[30]  S. Book Scaling toxicity from laboratory animals to people: an example with nitrogen dioxide. , 1982, Journal of toxicology and environmental health.

[31]  L. Daniel,et al.  EFFECT OF THE COPPER STATUS OF THE RAT ON THE COPPER-MOLYBDENUM-SULFATE INTERACTION. , 1964, The Journal of nutrition.

[32]  A. Renwick,et al.  Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine. , 1988, British journal of clinical pharmacology.

[33]  W. R. Stahl,et al.  Scaling of respiratory variables in mammals. , 1967, Journal of applied physiology.

[34]  P. Mcwilliams,et al.  APPLICATION OF REGRESSION ANALYSIS TO THE POWER FUNCTION , 1964 .

[35]  C. Richmond,et al.  Comparative metabolism of radionuclides in mammals. I. Uptake and retention of orally administered Zn65 by four mammalian species. , 1962, Health physics.

[36]  C C Travis,et al.  Interspecific scaling of toxicity data. , 1988, Risk analysis : an official publication of the Society for Risk Analysis.

[37]  B. Brodie Part VI. Difficulties in extrapolating data on metabolism of drugs from animal to man , 1962 .

[38]  B. Friis‐Hansen Body water compartments in children: changes during growth and related changes in body composition. , 1961, Pediatrics.

[39]  J. Huxley,et al.  Terminology of Relative Growth , 1936, Nature.

[40]  E. Buckingham On Physically Similar Systems; Illustrations of the Use of Dimensional Equations , 1914 .

[41]  R. Lutz,et al.  Physiological pharmacokinetics: an in vivo approach to membrane transport. , 1980, Pharmacology & therapeutics.

[42]  A. Heusner Energy metabolism and body size. I. Is the 0.75 mass exponent of Kleiber's equation a statistical artifact? , 1982, Respiration physiology.

[43]  H. Boxenbaum Time concepts in physics, biology, and pharmacokinetics. , 1986, Journal of Pharmacy and Science.

[44]  R K Jain,et al.  Physiologically based pharmacokinetic modeling: principles and applications. , 1983, Journal of pharmaceutical sciences.

[45]  D. Pinkel The use of body surface area as a criterion of drug dosage in cancer chemotherapy. , 1958, Cancer research.

[46]  M E Andersen,et al.  A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. , 1984, Toxicology and applied pharmacology.

[47]  D. Rall,et al.  Difficulties in extrapolating the results of toxicity studies in laboratory animals to man. , 1969, Environmental research.

[48]  H. Boxenbaum,et al.  Interspecies pharmacokinetic scaling, biological design and neoteny , 1990 .

[49]  J. Webster,et al.  The effect of age and cardiac failure on xamoterol pharmacokinetics. , 1988, British journal of clinical pharmacology.

[50]  K H Antonin,et al.  Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and rat. , 1976, The Journal of pharmacology and experimental therapeutics.

[51]  C. Teitelboim RADIATION REACTION AS A RETARDED SELF-INTERACTION. , 1971 .

[52]  P. N. Kugler,et al.  Similarity principles and intrinsic geometries: contrasting approaches to interspecies scaling. , 1986, Journal of pharmaceutical sciences.

[53]  R. Meglen,et al.  Molybdenum in the diet: an estimate of average daily intake in the United States. , 1980, The American journal of clinical nutrition.

[54]  S. Gould ALLOMETRY AND SIZE IN ONTOGENY AND PHYLOGENY , 1966, Biological reviews of the Cambridge Philosophical Society.

[55]  M Slavik,et al.  Quantitative prediction of drug toxicity in humans from toxicology in small and large animals. , 1975, Cancer research.

[56]  J. Mordenti,et al.  Pharmacokinetic scale-up: accurate prediction of human pharmacokinetic profiles from animal data. , 1985, Journal of pharmaceutical sciences.

[57]  W. Wieser,et al.  A distinction must be made between the ontogeny and the phylogeny of metabolism in order to understand the mass exponent of energy metabolism. , 1984, Respiration physiology.

[58]  L. Hahn The Relation of Blood Pressure to Weight, Height and Body Surface Area in Schoolboys Aged 11 to 15 Years , 1952, Archives of disease in childhood.

[59]  F. A. Smith,et al.  Physiologically based pharmacokinetics and the risk assessment process for methylene chloride. , 1987, Toxicology and applied pharmacology.

[60]  B. Brodie,et al.  Species, strain and sex differences in metabolism of hexobarbitone, amidopyrine, antipyrine and aniline , 1958 .

[61]  A. Butler,et al.  Simplification and improvement in estimating drug dosage and fluid and dietary allowances for patients of varying sizes. , 1960, The New England journal of medicine.

[62]  M. Williams,et al.  Interspecies comparison of acivicin pharmacokinetics. , 1988, Drug metabolism and disposition: the biological fate of chemicals.

[63]  J J Blum,et al.  On the geometry of four-dimensions and the relationship between metabolism and body mass. , 1977, Journal of theoretical biology.

[64]  M. Fujita,et al.  Comparative metabolism of cesium and potassium in mammals--interspecies correlation between body weight and equilibrium level. , 1966, Health physics.

[65]  P. D. Harwood Therapeutic Dosage in Small and Large Mammals. , 1963, Science.

[66]  B. Moore The Relationship of Dosage of a Drug to the Size of the Animal Treated, especially in regard to the Cause of the Failures to Cure Trypanosomiasis, and other Protozoan Diseases in Man and in Large Animals. , 1909, The Biochemical journal.

[67]  E. Calabrese Animal extrapolation and the challenge of human heterogeneity. , 1986, Journal of pharmaceutical sciences.

[68]  Galileo Galilei,et al.  Dialogues Concerning Two New Sciences , 1914 .

[69]  L. Bertalanffy Quantitative Laws in Metabolism and Growth , 1957 .

[70]  J. Wilson,et al.  Lack of scientific validity of body surface as basis for parenteral fluid dosage. , 1958, Journal of the American Medical Association.

[71]  D. Rall Relevance of animal experiments to humans. , 1979, Environmental health perspectives.

[72]  Koval'skiĭ Vv,et al.  [Modification of human and animal purine metabolism in conditions of various molybdenum bio-geochemical areas]. , 1961 .

[73]  M. Boddington An absolute metabolic scope for activity. , 1978, Journal of theoretical biology.

[74]  J. Prothero,et al.  Scaling of blood parameters in mammals , 1980 .

[75]  T. McMahon,et al.  Size and Shape in Biology , 1973, Science.

[76]  J. Mordenti Forecasting cephalosporin and monobactam antibiotic half-lives in humans from data collected in laboratory animals. , 1985, Antimicrobial Agents and Chemotherapy.