Regulation of Notch Signaling Activity
暂无分享,去创建一个
[1] Mark Rebeiz,et al. SCORE: A computational approach to the identification of cis-regulatory modules and target genes in whole-genome sequence data , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[2] S. Cohen,et al. Glycosyltransferase activity of Fringe modulates Notch–Delta interactions , 2000, Nature.
[3] E. Lai,et al. Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling. , 2001, Developmental cell.
[4] A. Xu,et al. An O-fucose site in the ligand binding domain inhibits Notch activation , 2003, Development.
[5] R. Haltiwanger,et al. Fringe Modifies O-Fucose on Mouse Notch1 at Epidermal Growth Factor-like Repeats within the Ligand-binding Site and the Abruptex Region* , 2003, The Journal of Biological Chemistry.
[6] Y. Jan,et al. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells , 1994, Cell.
[7] J. Lewis,et al. Notch signalling and the control of cell fate choices in vertebrates. , 1998, Seminars in cell & developmental biology.
[8] A. Parks,et al. Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. , 2000, Development.
[9] M. W. Young,et al. Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. , 1993, Genes & development.
[10] M. Cornell,et al. The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase. , 1999, Genetics.
[11] O. Pourquié. The Segmentation Clock: Converting Embryonic Time into Spatial Pattern , 2003, Science.
[12] K D Irvine,et al. Fringe, Notch, and making developmental boundaries. , 1999, Current opinion in genetics & development.
[13] M. Fortini,et al. Different cofactor activities in γ-secretase assembly , 2003, The Journal of Cell Biology.
[14] A. Xu,et al. Modulation of Notch-Ligand Binding by Protein O-Fucosyltransferase 1 and Fringe* , 2003, Journal of Biological Chemistry.
[15] J. A. Kaltschmidt,et al. Planar polarity and actin dynamics in the epidermis of Drosophila , 2002, Nature Cell Biology.
[16] J. Sklar,et al. TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms , 1991, Cell.
[17] M. Muskavitch,et al. Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development. , 1998, Molecular biology of the cell.
[18] K. Irvine,et al. Notch Ligands Are Substrates for ProteinO-Fucosyltransferase-1 and Fringe* , 2002, The Journal of Biological Chemistry.
[19] A. Caudy,et al. Regulation of Transcriptional Activation Domain Function by Ubiquitin , 2001, Science.
[20] J. Sklar,et al. Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors , 2000, Molecular and Cellular Biology.
[21] J. Bonifacino,et al. Ubiquitin and the control of protein fate in the secretory and endocytic pathways. , 1998, Annual review of cell and developmental biology.
[22] M. Gonzalez-Gaitan,et al. The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. , 2002, Developmental cell.
[23] G M Rubin,et al. Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta. , 2001, Developmental cell.
[24] J. Shioi,et al. A CBP Binding Transcriptional Repressor Produced by the PS1/ϵ-Cleavage of N-Cadherin Is Inhibited by PS1 FAD Mutations , 2003, Cell.
[25] D. Maier,et al. Transcriptional repression by Suppressor of Hairless involves the binding of a Hairless-dCtBP complex in Drosophila , 2001, Current Biology.
[26] A. Ciechanover,et al. Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor* , 2001, The Journal of Biological Chemistry.
[27] M. Fortini,et al. Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex. , 2003, The Journal of cell biology.
[28] D. Selkoe,et al. The Notch Ligands, Jagged and Delta, Are Sequentially Processed by α-Secretase and Presenilin/γ-Secretase and Release Signaling Fragments* , 2003, Journal of Biological Chemistry.
[29] Utpal Banerjee,et al. An EGFR/Ebi/Sno Pathway Promotes Delta Expression by Inactivating Su(H)/SMRTER Repression during Inductive Notch Signaling , 2002, Cell.
[30] B. Strooper,et al. Aph-1, Pen-2, and Nicastrin with Presenilin Generate an Active γ-Secretase Complex , 2003, Neuron.
[31] F. Schweisguth,et al. Repression by suppressor of hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo. , 2000, Genes & development.
[32] J. Posakony. Nature versus nurture: Asymmetric cell divisions in Drosophila bristle development , 1994, Cell.
[33] S. Barolo,et al. Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless. , 2002, Genes & development.
[34] R. Evans,et al. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. , 1998, Genes & development.
[35] T. Kudo,et al. Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1. , 2002, The EMBO journal.
[36] K. Irvine,et al. Fringe modulates Notch–ligand interactions , 1997, Nature.
[37] C. Doe,et al. Numb Antagonizes Notch Signaling to Specify Sibling Neuron Cell Fates , 1996, Neuron.
[38] T. Hunter,et al. Recognition and Ubiquitination of Notch by Itch, a Hect-type E3 Ubiquitin Ligase* , 2000, The Journal of Biological Chemistry.
[39] T. Kudo,et al. Presenilins mediate a dual intramembranous γ‐secretase cleavage of Notch‐1 , 2002 .
[40] Cheryl Wolting,et al. LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin‐dependent degradation , 2002, The EMBO journal.
[41] J. Kimble,et al. LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway , 2000, Nature.
[42] S. Artavanis-Tsakonas,et al. Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor , 1993, Cell.
[43] B. de Strooper,et al. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex. , 2003, Neuron.
[44] A. Israël,et al. Siah-1 binds and regulates the function of Numb , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[45] S. Bray,et al. Notch pathway: Making sense of Suppressor of Hairless , 2001, Current Biology.
[46] D. Selkoe,et al. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments. , 2003, The Journal of biological chemistry.
[47] Yang Wang,et al. Fringe is a glycosyltransferase that modifies Notch , 2000, Nature.
[48] Christin E Bland,et al. Notch-induced Proteolysis and Nuclear Localization of the Delta Ligand* , 2003, The Journal of Biological Chemistry.
[49] S. Sisodia,et al. The Notch Ligands, Delta1 and Jagged2, Are Substrates for Presenilin-dependent “γ-Secretase” Cleavage* , 2003, The Journal of Biological Chemistry.
[50] S. Bray,et al. Notch signalling in Drosophila: three ways to use a pathway. , 1998, Seminars in cell & developmental biology.
[51] Keith Brennan,et al. CSL-independent Notch signalling: a checkpoint in cell fate decisions during development? , 2002, Current opinion in genetics & development.
[52] I. Greenwald,et al. Interchangeability of Caenorhabditis elegans DSL proteins and intrinsic signalling activity of their extracellular domains in vivo. , 1995, Development.
[53] M. Gurney,et al. The Notch Intracellular Domain Is Ubiquitinated and Negatively Regulated by the Mammalian Sel-10 Homolog* , 2001, The Journal of Biological Chemistry.
[54] S. Artavanis-Tsakonas,et al. Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. , 1994, Development.
[55] M. Gurney,et al. SEL-10 Is an Inhibitor of Notch Signaling That Targets Notch for Ubiquitin-Mediated Protein Degradation , 2001, Molecular and Cellular Biology.
[56] J. Skeath,et al. Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. , 2003, Developmental cell.
[57] Christel Brou,et al. The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase. , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[58] G. Struhl,et al. Intrinsic activity of the lin-12 and Notch intracellular domains in vivo , 1993, Cell.
[59] P. Simpson,et al. Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions. , 1993, Development.
[60] T. Klein,et al. An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila. , 1997, Developmental biology.
[61] Y. Jan,et al. Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and Notch , 1996, Neuron.
[62] S. Carroll,et al. Fringe forms a complex with Notch , 2000, Nature.
[63] S. Artavanis-Tsakonas,et al. Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. , 1997, Development.
[64] S. Artavanis-Tsakonas,et al. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. , 1995, Development.
[65] H. Okano,et al. Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. , 2002, Development.
[66] P. Rakic,et al. The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[67] K. Irvine,et al. Regulation of Notch Signaling by O-Linked Fucose , 2002, Cell.
[68] S. Bray,et al. Spatially restricted factors cooperate with notch in the regulation of Enhancer of split genes. , 2000, Developmental biology.
[69] G. Wu,et al. sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. , 1997, Genes & development.
[70] Joseph L Goldstein,et al. Regulated Intramembrane Proteolysis A Control Mechanism Conserved from Bacteria to Humans , 2000, Cell.
[71] S. Artavanis-Tsakonas,et al. Notch signaling: cell fate control and signal integration in development. , 1999, Science.
[72] R. J. Fleming,et al. Structural conservation of Notch receptors and ligands. , 1998, Seminars in cell & developmental biology.
[73] P. Rakic,et al. Processing of the notch ligand delta by the metalloprotease Kuzbanian. , 1999, Science.
[74] Christel Brou,et al. Signalling downstream of activated mammalian Notch , 1995, Nature.
[75] Christel Brou,et al. The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and γ-secretase , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[76] P. Heitzler,et al. Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate , 2001, Current Biology.
[77] A. Israël,et al. The Notch1 receptor is cleaved constitutively by a furin-like convertase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[78] R. Fehon,et al. Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. , 1993, Development.
[79] A Cumano,et al. A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. , 2000, Molecular cell.
[80] M. Fortini. Notch and presenilin: a proteolytic mechanism emerges. , 2001, Current opinion in cell biology.
[81] J. Shioi,et al. A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. , 2003, Cell.
[82] S. Noselli. JNK signaling and morphogenesis in Drosophila. , 1998, Trends in Genetics.
[83] F. Schweisguth,et al. Notch Signaling: Endocytosis Makes Delta Signal Better , 2003, Current Biology.
[84] O. Ohara,et al. Intracellular cell-autonomous association of Notch and its ligands: a novel mechanism of Notch signal modification. , 2002, Developmental biology.
[85] F. Schweisguth,et al. Unequal segregation of Neuralized biases Notch activation during asymmetric cell division. , 2003, Developmental cell.
[86] Raphael Kopan,et al. A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1. , 2000, Molecular cell.
[87] P. Rakic,et al. The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[88] A. Joutel,et al. Notch signalling pathway and human diseases. , 1998, Seminars in cell & developmental biology.
[89] M. W. Young,et al. kuzbanian-mediated cleavage of Drosophila Notch. , 2002, Genes & development.
[90] N. Perrimon,et al. neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions , 2003, Development.
[91] P. Stanley,et al. Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[92] S. Blair,et al. The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate. , 1997, Development.
[93] J. Hsieh,et al. CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[94] F. Schweisguth,et al. Dominant-negative mutation in the beta2 and beta6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[95] A. Martinez-Arias,et al. An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila , 1999, Current Biology.
[96] Iva Greenwald,et al. Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans , 2002, Nature.
[97] P. Pelicci,et al. Numb Is an Endocytic Protein , 2000, The Journal of cell biology.
[98] Raphael Kopan,et al. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain , 1998, Nature.
[99] G. Struhl,et al. Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. , 2000, Molecular cell.
[100] S. Bray,et al. The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe. , 2000, Development.
[101] P. Simpson,et al. Requirement for dynamin during Notch signaling in Drosophila neurogenesis. , 1997, Developmental biology.
[102] S. Artavanis-Tsakonas,et al. Down-regulation of Delta by proteolytic processing , 2002, The Journal of cell biology.
[103] K. Irvine,et al. Notch activity in neural cells triggered by a mutant allele with altered glycosylation , 2003, Development.
[104] C. Goodman,et al. Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. , 1995, Development.
[105] N. Moschonas,et al. neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis. , 2001, Developmental cell.
[106] Daniel R. Foltz,et al. Glycogen Synthase Kinase-3β Modulates Notch Signaling and Stability , 2002, Current Biology.
[107] Cheol‐Hee Kim,et al. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. , 2003, Developmental cell.