Human umbilical cord mesenchymal stem cell-derived small extracellular vesicles ameliorate collagen-induced arthritis via immunomodulatory T lymphocytes.

[1]  A. Alunno,et al.  One year in review 2020: pathogenesis of rheumatoid arthritis. , 2020, Clinical and experimental rheumatology.

[2]  S. Chand,et al.  Mesenchymal Stem Cell-Derived Extracellular Vesicles: Challenges in Clinical Applications , 2020, Frontiers in Cell and Developmental Biology.

[3]  Chun-Chieh Huang,et al.  Evaluating the Endocytosis and Lineage-Specification Properties of Mesenchymal Stem Cell Derived Extracellular Vesicles for Targeted Therapeutic Applications , 2020, Frontiers in Pharmacology.

[4]  Qingjun Wei,et al.  The therapeutic effects of edaravone on collagen‐induced arthritis in rats , 2020, Journal of cellular biochemistry.

[5]  N. Arsenijević,et al.  Mesenchymal Stem Cell-Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases , 2019, Cells.

[6]  Pei Yang,et al.  Th17 cell pathogenicity and plasticity in rheumatoid arthritis , 2019, Journal of leukocyte biology.

[7]  Weiping Zhu,et al.  Bone marrow-derived mesenchymal stem cells-secreted exosomal microRNA-192-5p delays inflammatory response in rheumatoid arthritis. , 2019, International immunopharmacology.

[8]  D. Ma,et al.  Immunomodulatory effect of human umbilical cord mesenchymal stem cells on T lymphocytes in rheumatoid arthritis. , 2019, International immunopharmacology.

[9]  Monique A J van Eijndhoven,et al.  Exosomes , 2010, Annual review of biochemistry.

[10]  C. Malemud Defective T-Cell Apoptosis and T-Regulatory Cell Dysfunction in Rheumatoid Arthritis , 2018, Cells.

[11]  Fuhua Yan,et al.  Therapeutic Potential of Mesenchymal Cell–Derived miRNA-150-5p–Expressing Exosomes in Rheumatoid Arthritis Mediated by the Modulation of MMP14 and VEGF , 2018, The Journal of Immunology.

[12]  K. Kang,et al.  Intravenous Infusion of Umbilical Cord Blood‐Derived Mesenchymal Stem Cells in Rheumatoid Arthritis: A Phase Ia Clinical Trial , 2018, Stem cells translational medicine.

[13]  Takayuki Sumida,et al.  Review: Transcriptional Regulation of CD4+ T Cell Differentiation in Experimentally Induced Arthritis and Rheumatoid Arthritis , 2018, Arthritis & rheumatology.

[14]  C. Jorgensen,et al.  Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis , 2018, Theranostics.

[15]  I. Martin,et al.  Ectopic bone formation by aggregated mesenchymal stem cells from bone marrow and adipose tissue: A comparative study , 2018, Journal of tissue engineering and regenerative medicine.

[16]  R. Caporali,et al.  The management of first-line biologic therapy failures in rheumatoid arthritis: Current practice and future perspectives. , 2017, Autoimmunity reviews.

[17]  T. Ritter,et al.  Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning? , 2017, Front. Immunol..

[18]  S. Kotake,et al.  The Plasticity of Th17 Cells in the Pathogenesis of Rheumatoid Arthritis , 2017, Journal of clinical medicine.

[19]  C. Jorgensen,et al.  Pathogenic or Therapeutic Extracellular Vesicles in Rheumatic Diseases: Role of Mesenchymal Stem Cell-Derived Vesicles , 2017, International journal of molecular sciences.

[20]  C. De Bari,et al.  Mesenchymal stem cells for the management of rheumatoid arthritis: immune modulation, repair or both? , 2017, Current opinion in rheumatology.

[21]  Lingyun Sun,et al.  Comparable therapeutic potential of umbilical cord mesenchymal stem cells in collagen-induced arthritis to TNF inhibitor or anti-CD20 treatment. , 2017, Clinical and experimental rheumatology.

[22]  S. Marsal,et al.  Intravenous administration of expanded allogeneic adipose-derived mesenchymal stem cells in refractory rheumatoid arthritis (Cx611): results of a multicentre, dose escalation, randomised, single-blind, placebo-controlled phase Ib/IIa clinical trial , 2016, Annals of the rheumatic diseases.

[23]  G. Camussi,et al.  Stem Cell-Derived Extracellular Vesicles and Immune-Modulation , 2016, Front. Cell Dev. Biol..

[24]  Yaojiong Wu,et al.  Excess Integrins Cause Lung Entrapment of Mesenchymal Stem Cells , 2015, Stem cells.

[25]  T. Tonn,et al.  Extracellular vesicles secreted by bone marrow- and adipose tissue-derived mesenchymal stromal cells fail to suppress lymphocyte proliferation. , 2015, Stem Cells and Development.

[26]  M. Scarsella,et al.  Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro. , 2014, Stem cells and development.

[27]  M. Porta,et al.  Human mesenchymal stem cell-derived microvesicles modulate T cell response to islet antigen glutamic acid decarboxylase in patients with type 1 diabetes , 2014, Diabetologia.

[28]  A. Tyndall Mesenchymal stem cell treatments in rheumatology—a glass half full? , 2014, Nature Reviews Rheumatology.

[29]  H. Nie,et al.  Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis , 2013, Nature Medicine.

[30]  Z. Amoura,et al.  Human FoxP3+ regulatory T cells in systemic autoimmune diseases. , 2011, Autoimmunity reviews.

[31]  Y. Yoon,et al.  Malignant Tumor Formation After Transplantation of Short-Term Cultured Bone Marrow Mesenchymal Stem Cells in Experimental Myocardial Infarction and Diabetic Neuropathy , 2011, Circulation research.

[32]  D. Brand,et al.  Collagen-induced arthritis , 2007, Nature Protocols.

[33]  Y. Wang,et al.  Accumulation of FoxP3‐expressing CD4+CD25+ T cells with distinct chemokine receptors in synovial fluid of patients with active rheumatoid arthritis , 2007, Scandinavian journal of rheumatology.

[34]  D. Kimpel,et al.  Splenectomy attenuates streptococcal cell wall-induced arthritis and alters leukocyte activation. , 2003, Arthritis and rheumatism.