Anaphylaxis during the first course of high‐dose methotrexate: a case report and literature review

What is known and Objective:  Methotrexate (MTX) is widely used in the management of paediatric cancer with a generally favourable benefit/risk profile. We report an unusual adverse drug reaction with the first course of high‐dose MTX in a paediatric patient and review the literature for similar cases.

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