Multiple gene variants linked to Alzheimer’s-type clinical dementia via GWAS are also associated with non-Alzheimer’s neuropathologic entities

[1]  Janna H. Neltner,et al.  Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts , 2022, Acta Neuropathologica.

[2]  H. Shang,et al.  Shared genetic links between frontotemporal dementia and psychiatric disorders , 2022, BMC Medicine.

[3]  Jae-Bong Park,et al.  Cross-Talk between Wnt Signaling and Src Tyrosine Kinase , 2022, Biomedicines.

[4]  J. Masdeu,et al.  Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies , 2022, Acta Neuropathologica.

[5]  Nick C Fox,et al.  New insights into the genetic etiology of Alzheimer’s disease and related dementias , 2022, Nature Genetics.

[6]  Kwun Chuen Gary Chan,et al.  Limbic-Predominant Age-Related TDP-43 Encephalopathy , 2022, Neurology.

[7]  N. Wray,et al.  Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1 , 2022, Genome Medicine.

[8]  C. van Broeckhoven,et al.  Investigating the Endo-Lysosomal System in Major Neurocognitive Disorders Due to Alzheimer’s Disease, Frontotemporal Lobar Degeneration and Lewy Body Disease: Evidence for SORL1 as a Cross-Disease Gene , 2021, International journal of molecular sciences.

[9]  Kevin L. Boehme,et al.  Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study , 2021, Acta neuropathologica communications.

[10]  F. Schmitt,et al.  Four Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies. , 2021, Journal of Alzheimer's disease : JAD.

[11]  J. Schneider,et al.  To what degree is late life cognitive decline driven by age-relatedneuropathologies? , 2021, Brain : a journal of neurology.

[12]  Rupal I. Mehta,et al.  What is ‘Alzheimer's disease’? The neuropathological heterogeneity of clinically defined Alzheimer's dementia , 2021, Current opinion in neurology.

[13]  K. Jellinger,et al.  Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study , 2021, Acta Neuropathologica.

[14]  Kevin L. Boehme,et al.  Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy , 2020, Acta Neuropathologica.

[15]  N. Hempel,et al.  Extracellular Glutathione Peroxidase GPx3 and Its Role in Cancer , 2020, Cancers.

[16]  Charles C. White,et al.  Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology , 2020, Neuron.

[17]  M. Lardelli,et al.  Sorting Out the Role of the Sortilin-Related Receptor 1 in Alzheimer’s Disease , 2020, Journal of Alzheimer's disease reports.

[18]  C. Jack,et al.  Reply: LATE to the PART-y. , 2019, Brain : a journal of neurology.

[19]  M. Grossman,et al.  LATE to the PART-y , 2019, Brain : a journal of neurology.

[20]  C. Jack,et al.  Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report , 2019, Brain : a journal of neurology.

[21]  D. Campion,et al.  SORL1 genetic variants and Alzheimer disease risk: a literature review and meta-analysis of sequencing data , 2019, Acta Neuropathologica.

[22]  Brian E. Cade,et al.  Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program , 2019, Nature.

[23]  S. Leurgans,et al.  Attributable risk of Alzheimer's dementia attributed to age‐related neuropathologies , 2018, Annals of neurology.

[24]  G. Schellenberg,et al.  Quality Control and Integration of Genotypes from Two Calling Pipelines for Whole Genome Sequence Data in the Alzheimer’s Disease Sequencing Project , 2018, bioRxiv.

[25]  R. Shamilov,et al.  TNIP1 in Autoimmune Diseases: Regulation of Toll-like Receptor Signaling , 2018, Journal of immunology research.

[26]  Lilah M. Besser,et al.  The Revised National Alzheimer’s Coordinating Center’s Neuropathology Form—Available Data and New Analyses , 2018, Journal of neuropathology and experimental neurology.

[27]  David A Bennett,et al.  Religious Orders Study and Rush Memory and Aging Project. , 2018, Journal of Alzheimer's disease : JAD.

[28]  Clifford R. Jack,et al.  The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable , 2018, Alzheimer's & Dementia.

[29]  T. Montine,et al.  Alzheimer's Disease Sequencing Project discovery and replication criteria for cases and controls: Data from a community-based prospective cohort study with autopsy follow-up , 2017, Alzheimer's & Dementia.

[30]  P. Visscher,et al.  Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis , 2017, Nature Communications.

[31]  P. Hines,et al.  Late to the Party , 2020 .

[32]  K. Sleegers,et al.  Identification and description of three families with familial Alzheimer disease that segregate variants in the SORL1 gene , 2017, Acta Neuropathologica Communications.

[33]  R. Hubbard,et al.  Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample , 2017, Alzheimer's & Dementia.

[34]  Gerard D. Schellenberg,et al.  Genomic variants, genes, and pathways of Alzheimer's disease: An overview , 2017, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[35]  F. Schmitt,et al.  Challenges and Considerations Related to Studying Dementia in Blacks/African Americans. , 2017, Journal of Alzheimer's disease : JAD.

[36]  O. Andreassen,et al.  Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases , 2016, Journal of Neurology, Neurosurgery & Psychiatry.

[37]  D. Bennett,et al.  TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia. , 2016, Brain : a journal of neurology.

[38]  J. Schneider,et al.  Relation of genomic variants for Alzheimer disease dementia to common neuropathologies , 2016, Neurology.

[39]  Charles D. Smith,et al.  “New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS) , 2016, Journal of neuropathology and experimental neurology.

[40]  Timothy J. Hohman,et al.  Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk , 2016, Alzheimer's & Dementia.

[41]  A. Fagan,et al.  Suspected non-Alzheimer disease pathophysiology — concept and controversy , 2016, Nature Reviews Neurology.

[42]  Janna H. Neltner,et al.  Brain pathologies in extreme old age , 2016, Neurobiology of Aging.

[43]  Mitchell J. Machiela,et al.  LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants , 2015, Bioinform..

[44]  Richard J. Kryscio,et al.  Self-reported memory complaints: A comparison of demented and unimpaired outcomes , 2015, Alzheimer's & Dementia.

[45]  K. Jellinger,et al.  PART, a distinct tauopathy, different from classical sporadic Alzheimer disease , 2015, Acta Neuropathologica.

[46]  Sally R. Ellingson,et al.  Reassessment of Risk Genotypes (GRN, TMEM106B, and ABCC9 Variants) Associated With Hippocampal Sclerosis of Aging Pathology , 2015, Journal of neuropathology and experimental neurology.

[47]  Carson C Chow,et al.  Second-generation PLINK: rising to the challenge of larger and richer datasets , 2014, GigaScience.

[48]  Wei‐Ju Lee,et al.  ABCA7 gene and the risk of Alzheimer's disease in Han Chinese in Taiwan , 2014, Neurobiology of Aging.

[49]  Margaret A. Pericak-Vance,et al.  Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias , 2014, PLoS genetics.

[50]  Charles D. Smith,et al.  ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology , 2014, Acta Neuropathologica.

[51]  T. Willnow,et al.  Sorting receptor SORLA – a trafficking path to avoid Alzheimer disease , 2013, Journal of Cell Science.

[52]  Oscar L Lopez,et al.  Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. , 2013, JAMA.

[53]  J. Morris,et al.  Clinicopathologic study of Alzheimer's disease: Alzheimer mimics. , 2013, Journal of Alzheimer's disease : JAD.

[54]  W. Kukull,et al.  Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010 , 2012, Journal of neuropathology and experimental neurology.

[55]  Robert C Green,et al.  A comprehensive genetic association study of Alzheimer disease in African Americans. , 2011, Archives of neurology.

[56]  Karen Marder,et al.  Genome-Wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population , 2011, BMC Medical Genetics.

[57]  Charles D. Smith,et al.  Hippocampal sclerosis in advanced age: clinical and pathological features. , 2011, Brain : a journal of neurology.

[58]  J. Morris,et al.  The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[59]  Charles Duyckaerts,et al.  National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach , 2011, Acta Neuropathologica.

[60]  D. Altshuler,et al.  A map of human genome variation from population-scale sequencing , 2010, Nature.

[61]  Charles D. Smith,et al.  Modeling the Association between 43 Different Clinical and Pathological Variables and the Severity of Cognitive Impairment in a Large Autopsy Cohort of Elderly Persons , 2010, Brain pathology.

[62]  R. Castellani,et al.  Alzheimer disease. , 2010, Disease-a-month : DM.

[63]  S. Haneuse,et al.  Adjustment for Selection Bias in Observational Studies with Application to the Analysis of Autopsy Data , 2009, Neuroepidemiology.

[64]  M. Katoh WNT signaling in stem cell biology and regenerative medicine. , 2008, Current drug targets.

[65]  Peter T Nelson,et al.  Clinicopathologic Correlations in a Large Alzheimer Disease Center Autopsy Cohort: Neuritic Plaques and Neurofibrillary Tangles "Do Count" When Staging Disease Severity , 2007, Journal of neuropathology and experimental neurology.

[66]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[67]  D. Dickson,et al.  TDP‐43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease , 2007, Annals of neurology.

[68]  Clifford R Jack,et al.  Rates of cerebral atrophy differ in different degenerative pathologies. , 2006, Brain : a journal of neurology.

[69]  Bruce L. Miller,et al.  Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis , 2006, Science.

[70]  L. Fratiglioni,et al.  Role of genes and environments for explaining Alzheimer disease. , 2006, Archives of general psychiatry.

[71]  O. Lopez,et al.  Genetic association between the APOE*4 allele and Lewy bodies in Alzheimer disease , 2005, Neurology.

[72]  H. Braak,et al.  Alzheimer's disease affects limbic nuclei of the thalamus , 2004, Acta Neuropathologica.

[73]  G. Schellenberg,et al.  Head injury and risk of Alzheimer's disease by apolipoprotein E genotype. , 1997, American journal of epidemiology.

[74]  S. Mirra The CERAD Neuropathology Protocol and Consensus Recommendations for the Postmortem Diagnosis of Alzheimer’s Disease: A Commentary , 1997, Neurobiology of Aging.

[75]  G. Schellenberg,et al.  Apolipoprotein E in Alzheimer's disease risk and case detection: a case-control study. , 1996, Journal of clinical epidemiology.

[76]  S. M. Sumi,et al.  The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) , 1991, Neurology.