Phaeochromocytoma in Children

Tevetoglu and Lee (1956) and Cone, Allen and Pearson (1957) together collected 46 cases of phaeochromocytoma occurring in children under the age of 14 years. Since then a further 12 cases have been reported (Robinson and Williams, 1956; Spencer, Wyatt and Chisholm, 1956; Shocket and Teloh, 1957; Higgins, 1957; Slocombe, 1957; Linke, Rosenthal and Kiefer, 1958; Galloway, Martens, Dimmette, Kenney and Cone, 1959; Greenberg and Gardner, 1959; Nikolaev and Belikhova, 1959; Harlem, 1960; Maclaurin and Arneil, 1961). This paper describes four previously-unreported cases of phaeochromocytoma from the Birmingham Children's Hospital and includes also a review of other reported cases in children with regard to sex and age incidence, multiplicity and sites of tumours. The differential diagnosis is mentioned briefly. The investigations used in the diagnosis of phaeochromocytomas and their subsequent localization within the body are discussed in more detail. The danger to life of hypertensive crisis by the time the case reaches hospital care and the great value of 'rogitine' (phentolamine) in pre-operative management are emphasized. The monitoring of blood pressure and its control with phentolamine and noradrenaline during the operation for the removal of the tumour are described.

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