Combination of the new minor groove alkylator tallimustine and melphalan.

[1]  Nicola Mongelli,et al.  DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin , 1995, Nucleic Acids Res..

[2]  F. Cavalli,et al.  Phase I study of the novel distamycin derivative tallimustine (FCE 24517). , 1994, Annals of oncology : official journal of the European Society for Medical Oncology.

[3]  R. Souhami,et al.  DNA damage by anti-cancer agents resolved at the nucleotide level of a single copy gene: evidence for a novel binding site for cisplatin in cells. , 1994, Nucleic acids research.

[4]  H. Coley,et al.  The effects of a benzoic acid mustard derivative of distamycin A (FCE 24517) and related minor groove-binding distamycin analogues on the activity of major groove-binding alkylating agents. , 1993, Biochemical pharmacology.

[5]  R. Souhami,et al.  Measurement of the sequence specificity of covalent DNA modification by antineoplastic agents using Taq DNA polymerase. , 1991, Nucleic acids research.

[6]  R. Souhami,et al.  Effect of ionic strength and cationic DNA affinity binders on the DNA sequence selective alkylation of guanine N7-positions by nitrogen mustards. , 1990, Biochemistry.

[7]  M. D’Incalci,et al.  Importance of the DNA repair enzyme O6-alkyl guanine alkyltransferase (AT) in cancer chemotherapy. , 1988, Cancer treatment reviews.

[8]  K. Kohn,et al.  DNA cross-linking responses of human malignant glioma cell strains to chloroethylnitrosoureas, cisplatin, and diaziquone. , 1987, Cancer research.

[9]  W. Mattes,et al.  DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards. , 1986, Nucleic acids research.

[10]  L. Hurley,et al.  Reaction of the antitumor antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity. , 1985, Biochemistry.

[11]  K. Kohn,et al.  DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells , 1980, Nature.

[12]  K. Kohn,et al.  DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity. , 1979, Cancer research.

[13]  K. Kohn.  Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas. , 1977, Cancer research.

[14]  M. Broggini,et al.  Selective DNA interaction of the novel distamycin derivative FCE 24517. , 1991, Cancer research.

[15]  B. Teicher,et al.  Preclinical studies relating to the use of thiotepa in the high-dose setting alone and in combination. , 1990, Seminars in oncology.

[16]  B. Teicher,et al.  Combination of N,N',N"-triethylenethiophosphoramide and cyclophosphamide in vitro and in vivo. , 1988, Cancer research.