Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

[1]  M. Mildner,et al.  Extracellular vesicles in human skin: cross-talk from senescent fibroblasts to keratinocytes by miRNAs. , 2019, The Journal of investigative dermatology.

[2]  P. Thurner,et al.  Calibration of colloidal probes with atomic force microscopy for micromechanical assessment. , 2018, Journal of the mechanical behavior of biomedical materials.

[3]  O. Dreesen,et al.  Biomarkers of Cellular Senescence and Skin Aging , 2018, Front. Genet..

[4]  F. Gruber,et al.  Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype , 2018, Aging.

[5]  F. Gruber,et al.  Blocking negative effects of senescence in human skin fibroblasts with a plant extract , 2018, npj Aging and Mechanisms of Disease.

[6]  J. Popp,et al.  Raman and infrared spectroscopy differentiate senescent from proliferating cells in a human dermal fibroblast 3D skin model. , 2017, The Analyst.

[7]  Emilie Bauwens,et al.  The impact of cellular senescence in skin ageing: A notion of mosaic and therapeutic strategies , 2017, Biochemical pharmacology.

[8]  J. Popp,et al.  Raman and Infrared Spectroscopy Distinguishing Replicative Senescent from Proliferating Primary Human Fibroblast Cells by Detecting Spectral Differences Mainly Due to Biomolecular Alterations. , 2017, Analytical chemistry.

[9]  R. Westendorp,et al.  Secreted microvesicular miR‐31 inhibits osteogenic differentiation of mesenchymal stem cells , 2016, Aging cell.

[10]  J. Diekmann,et al.  A three‐dimensional skin equivalent reflecting some aspects of in vivo aged skin , 2016, Experimental dermatology.

[11]  S. Aho,et al.  p16INK4A Influences the Aging Phenotype in the Living Skin Equivalent , 2013, The Journal of investigative dermatology.

[12]  R. Willemze,et al.  Effects of serially passaged fibroblasts on dermal and epidermal morphogenesis in human skin equivalents , 2013, Biogerontology.

[13]  D. Lewis,et al.  Reversing the aging stromal phenotype prevents carcinoma initiation , 2011, Aging.

[14]  P. Elsner,et al.  Dry skin, barrier function, and irritant contact dermatitis in the elderly. , 2011, Clinics in dermatology.

[15]  J. Campisi,et al.  The senescence-associated secretory phenotype: the dark side of tumor suppression. , 2010, Annual review of pathology.

[16]  Solène Mine,et al.  Aging Alters Functionally Human Dermal Papillary Fibroblasts but Not Reticular Fibroblasts: A New View of Skin Morphogenesis and Aging , 2008, PloS one.

[17]  M. Mildner,et al.  Gene silencing in a human organotypic skin model. , 2006, Biochemical and biophysical research communications.

[18]  W. Kuri-Harcuch,et al.  Interleukin-6 promotes human epidermal keratinocyte proliferation and keratin cytoskeleton reorganization in culture , 2006, Cell and Tissue Research.

[19]  G. Pharr,et al.  Measurement of hardness and elastic modulus by instrumented indentation: Advances in understanding and refinements to methodology , 2004 .

[20]  J. Remacle,et al.  Stress-induced premature senescence and tissue ageing. , 2002, Biochemical pharmacology.

[21]  C Roskelley,et al.  A biomarker that identifies senescent human cells in culture and in aging skin in vivo. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[22]  G. Kaplan,et al.  Novel responses of human skin to intradermal recombinant granulocyte/macrophage-colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth, and enhanced wound healing , 1992, The Journal of experimental medicine.

[23]  L. Hayflick.  THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS. , 1965, Experimental cell research.