Multiplexed, Disposable, Plastic Microfluidic Systems for High-Throughput Applications

Low-cost, mass-produced, plastic microfluidic devices are being developed for a variety of microfluidic applications including DNA analysis, drug discovery, and clinical diagnostics. Plastic substrates with complex patterns of 10–100μm-sized channels are reproducibly formed against mold tools fabricated by micromachining techniques. These substrates are used to produce plastic devices on which reactions and high-efficiency electrophoretic separations of biomolecules have been achieved in timescales of seconds to minutes.

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