Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor
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A. Waterson | D. Rudolph | M. Gmachl | N. Mischerikow | J. Böttcher | J. Phan | O. Krämer | C. Smethurst | F. Savarese | M. Mayer | T. Gerstberger | Harald Weinstabl | J. Abbott | A. Gollner | D. Kessler | A. Mantoulidis | Qi Sun | D. McConnell | K. Rumpel | Tobias Wunberg | Heribert Arnhof | Gerhard Gmaschitz | Lorenz Herdeis | Matthias Treu | Joachim Bröker | Andrew J Little | Stephen W Fesik | Thomas Gerstberger | Jark Böttcher