MRS classification based on independent component analysis and support vector machines

A novel scheme is proposed in this paper which combines independent component analysis (ICA) and support vector machines (SVM) to classify MRS. ICA is used to extract features by decomposing MRS into components which correspond to biomedical metabolites. SVM is used to train a classifier based on features extracted by ICA. The new scheme can extract meaningful features and therefore obtain a classifier with good generalization. Experimental results show that the new method has better performance than others previous ones.

[1]  T. Brown,et al.  A new method for spectral decomposition using a bilinear Bayesian approach. , 1999, Journal of magnetic resonance.

[2]  D. Arnold,et al.  Using pattern analysis of in vivo proton MRSI data to improve the diagnosis and surgical management of patients with brain tumors , 1998, NMR in biomedicine.

[3]  Pierre Comon,et al.  Independent component analysis, A new concept? , 1994, Signal Process..

[4]  U Edlund,et al.  Multivariate data analysis of NMR data. , 1991, Journal of pharmaceutical and biomedical analysis.

[5]  John R. Griffiths Japanese magnetic resonance research , 1997 .

[6]  Aapo Hyvärinen,et al.  Fast and robust fixed-point algorithms for independent component analysis , 1999, IEEE Trans. Neural Networks.

[7]  J. Suykens,et al.  Classification of brain tumours using short echo time 1H MR spectra. , 2004, Journal of magnetic resonance.

[8]  Truman R. Brown,et al.  Application of Principal-Component Analysis for NMR Spectral Quantitation , 1995 .

[9]  D. Chakrabarti,et al.  A fast fixed - point algorithm for independent component analysis , 1997 .

[10]  Vladimir Vapnik,et al.  Statistical learning theory , 1998 .

[11]  L. Mitschang,et al.  Signal selection in high-resolution NMR by pulsed field gradients. I. Geometrical analysis. , 1999, Journal of magnetic resonance.

[12]  G. Hagberg,et al.  From magnetic resonance spectroscopy to classification of tumors. A review of pattern recognition methods , 1998, NMR in biomedicine.

[13]  Sabine Van Huffel,et al.  Brain tumor classification based on long echo proton MRS signals , 2004, Artif. Intell. Medicine.

[14]  Erkki Oja,et al.  Independent component analysis: algorithms and applications , 2000, Neural Networks.

[15]  Terrence J. Sejnowski,et al.  An Information-Maximization Approach to Blind Separation and Blind Deconvolution , 1995, Neural Computation.

[16]  W. El-Deredy,et al.  Pattern recognition approaches in biomedical and clinical magnetic resonance spectroscopy: a review , 1997, NMR in biomedicine.