Single- and Multi-label Prediction of Burden on Families of Schizophrenia Patients

Whereas there exist questionnaires used to measure the level of anxiety or depression in caregivers of schizophrenia patients, sometimes these symptoms take too long to be detected and the treatment needed is more difficult than it would have been if the burden had been detected at an earlier stage. In this paper we propose the use of automatic classification techniques to predict the output of such questionnaires (Hamilton and ECFOS-II), making it possible to anticipate an appropriate treatment or advice for the family caregivers from Primary Care consultations. In particular, we apply standard (one class variable) and multi-dimensional classification approaches to predict caregiver anxiety, depression and answers to questionnaires. Our study has been carried out with a dataset containing data from 180 schizophrenia patients and their caregivers, and the results are very promising, obtaining accuracies of approximately 96%.

[1]  P. Martín,et al.  Validation of positive and negative symptom scale (PANSS) in a sample of Spanish schizophrenic patients , 1994 .

[2]  Murray A. Straus,et al.  The Dark Side of Families: Current Family Violence Research , 1983 .

[3]  C. Jenaro,et al.  Primary caregivers of schizophrenia outpatients: Burden and predictor variables , 2008, Psychiatry Research.

[4]  Joost N. Kok Machine Learning: ECML 2007, 18th European Conference on Machine Learning, Warsaw, Poland, September 17-21, 2007, Proceedings , 2007, ECML.

[5]  J. Ross Quinlan,et al.  C4.5: Programs for Machine Learning , 1992 .

[6]  Robert A Short,et al.  Burden in schizophrenia caregivers: impact of family psychoeducation and awareness of patient suicidality. , 2003, Family process.

[7]  J. Ramos-Brieva,et al.  A new validation of the Hamilton Rating Scale for Depression. , 1988, Journal of psychiatric research.

[8]  Grigorios Tsoumakas,et al.  MULAN: A Java Library for Multi-Label Learning , 2011, J. Mach. Learn. Res..

[9]  Grigorios Tsoumakas,et al.  Random k -Labelsets: An Ensemble Method for Multilabel Classification , 2007, ECML.

[10]  Grigorios Tsoumakas,et al.  Multi-Label Classification: An Overview , 2007, Int. J. Data Warehous. Min..

[11]  J. Goldstein,et al.  Gender and the course of schizophrenia: differences in treated outcomes. , 1990, Schizophrenia bulletin.

[12]  M. Hamilton The assessment of anxiety states by rating. , 1959, The British journal of medical psychology.

[13]  Victor R. Preedy,et al.  DSM-IV-TR , 2000 .

[14]  D. Dyck,et al.  Predictors of burden and infectious illness in schizophrenia caregivers. , 1999, Psychosomatic medicine.

[15]  Validation in Spanish population of the family objective and subjective burden interview (ECFOS-II) for relatives of patients with schizophrenia. , 2007, Actas espanolas de psiquiatria.