Characterization of a newly derived human sarcoma cell line (HT‐1080)

A tumor cell line was derived from the fibrosarcoma of a 35‐year‐old Caucasian man who died without having received chemotherapy or radiotherapy. The in vitro growth properties and transplantability into antithymocytic sera treated mice were characteristic of these malignant cells. An aberrant karyology with marker chromosomes was present. No virus particles were detected.

[1]  R. Huebner,et al.  Propagation of human tumors in antithymocyte serum-treated mice. , 1974, Journal of the National Cancer Institute.

[2]  M. Gardner,et al.  RD-114 virus compared with feline and murine type-C viruses released from RD cells. , 1973, Nature: New biology.

[3]  W. F. Simpson,et al.  Diploid and heteroploid human cell lines surveyed for Y chromosome fluorescence. , 1973, Nature: New biology.

[4]  C. Vogel,et al.  Kaposi's sarcoma: a new model in the search for viruses associated with human malignancies. , 1972, Journal of the National Cancer Institute.

[5]  A. Cork,et al.  Establishment in vitro of a human neurogenic sarcoma. , 1972, Cancer research.

[6]  E. Bloom.  Further definition by cytotoxicity tests of cell surface antigens of human sarcomas in culture. , 1972, Cancer research.

[7]  R. Huebner,et al.  C-type virus released from cultured human rhabdomyosarcoma cells. , 1972, Nature: New biology.

[8]  M. Seabright.  A rapid banding technique for human chromosomes. , 1971, Lancet.

[9]  C. Lin,et al.  A suggestion for the nomenclature of the fluorescent banding patterns in human metaphase chromosomes. , 1971, Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie.

[10]  L. Old,et al.  Human sarcomas in culture. Foci of altered cells and a common antigen; induction of foci and antigen in human fibroblast cultures by filtrates. , 1971 .

[11]  C. Bradt,et al.  Cultivation in vitro of cells derived from a human osteosarcoma , 1971, Cancer.

[12]  S. Aaronson,et al.  Human sarcoma cells in culture. Identification by colony-forming ability on monolayers of normal cells. , 1970, Experimental cell research.

[13]  S. Mizutani,et al.  Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus , 1970, Nature.

[14]  M. Gardner,et al.  Cultivation in vitro of cells derived from a human rhabdomyosarcoma , 1969, Cancer.

[15]  D. Morton,et al.  Human Liposarcomas: Tissue Cultures Containing Foci of Transformed Cells with Viral Particles , 1969, Science.

[16]  R. Huebner,et al.  Proteins of Rous sarcoma virus. , 1968, Virology.

[17]  A. Robinson,et al.  Glucose-6-phosphate Dehydrogenase Isoenzymes in Human Cell Cultures Determined by Sucrose-Agar Gel and Cellulose Acetate Zymograms∗ , 1968, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[18]  S. Gartler,et al.  Apparent HeLa Cell Contamination of Human Heteroploid Cell Lines , 1968, Nature.

[19]  S. Fedoroff.  Proposed usage of animal tissue culture terms. , 1975, Journal of the National Cancer Institute.

[20]  L. White,et al.  Chromosome changes in a rhabdomyosarcoma during recurrence and in cell culture. , 1967, British Journal of Cancer.

[21]  J. Pontén,et al.  Two established in vitro cell lines from human mesenchymal tumours , 1967, International journal of cancer.

[22]  G. Moore,et al.  The in Vitro Chromosome Constitution of Cells from Human Tumors , 1962 .

[23]  L. Siminovitch,et al.  An air-drying technique for flattening chromosomes in mammalian oells grown in vitro. , 1958, Stain technology.

[24]  K. Sanford,et al.  The growth in vitro of single isolated tissue cells. , 1948, Journal of the National Cancer Institute.