Language comprehension and working memory language comprehension and working memory deficits in patients with schizophrenia

The present study examined the hypothesis that patients with schizophrenia have deficits in language comprehension compared to normal controls, and that these deficits are associated with disturbances in working memory (WM). In addition, we hypothesized that language comprehension deficits would be associated with the severity of specific symptoms in the patients (formal thought disorder and hallucinations). Participants were 27 stable outpatients with schizophrenia and 28 demographically similar controls. Language comprehension was measured by presenting sentences auditorily that varied in length and syntactic complexity, followed by two or three comprehension questions. We measured working memory by administering a reading span task. Results indicated that, as predicted, language comprehension deficits were significantly greater in patients with schizophrenia than controls. Also as predicted, working memory was strongly correlated with language comprehension performance in both patients with schizophrenia and controls. Contrary to our predictions, language comprehension and working memory deficits were not associated with either formal thought disorder or hallucinations.

[1]  R. Hoffman,et al.  Working memory, attention, and communication disturbances in schizophrenia. , 1996, Journal of abnormal psychology.

[2]  M A Just,et al.  The capacity theory of comprehension: new frontiers of evidence and arguments. , 1996, Psychological review.

[3]  Don McNicol,et al.  The Comprehension and Production of Complex Syntax in Schizophrenia , 1985, Cortex.

[4]  Sohee Park,et al.  Schizophrenics show spatial working memory deficits. , 1992, Archives of general psychiatry.

[5]  S. Steinhauer,et al.  Language comprehension in schizophrenia: Trait or state indicator? , 1995, Biological Psychiatry.

[6]  R Fog,et al.  Schizophrenia Research , 2015 .

[7]  Kenneth S. Kendler,et al.  Positive and negative symptoms in schizophrenia , 1984, Psychiatry Research.

[8]  Matthew Flatt,et al.  PsyScope: An interactive graphic system for designing and controlling experiments in the psychology laboratory using Macintosh computers , 1993 .

[9]  M. Just,et al.  From the SelectedWorks of Marcel Adam Just 1992 A capacity theory of comprehension : Individual differences in working memory , 2017 .

[10]  J. J. Ryan,et al.  Wechsler Adult Intelligence Scale-III , 2001 .

[11]  M. Just,et al.  A capacity approach to syntactic comprehension disorders: making normal adults perform like aphasic patients , 1994 .

[12]  M. Just,et al.  Individual differences in syntactic processing: The role of working memory , 1991 .

[13]  N. Andreasen,et al.  Scale for the assessment of thought, language, and communication (TLC). , 2021, Schizophrenia bulletin.

[14]  B. Johnstone,et al.  The comparability of the WRAT-R reading test and NAART as estimates of premorbid intelligence in neurologically impaired patients. , 1996, Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists.

[15]  S. Steinhauer,et al.  Working memory capacity predicts language comprehension in schizophrenic patients , 1996, Schizophrenia Research.

[16]  J. Cohen,et al.  Relation of prefrontal cortex dysfunction to working memory and symptoms in schizophrenia. , 2001, The American journal of psychiatry.

[17]  A. Wiens,et al.  Estimating WAIS-R FSIQ from the national adult reading test-revised in normal subjects , 1993 .

[18]  D. Wechsler.  Wechsler Adult Intelligence Scale , 2021, Encyclopedia of Evolutionary Psychological Science.

[19]  T. Goldberg,et al.  Auditory working memory and Wisconsin Card Sorting Test performance in schizophrenia. , 1997, Archives of general psychiatry.

[20]  Xiao-Li Meng,et al.  Comparing correlated correlation coefficients , 1992 .

[21]  Terry E. Goldberg,et al.  Prefrontal function and schizophrenic symptoms , 1992 .

[22]  S. Steinhauer,et al.  language comprehension in schizophrenics and their brothers , 1992, Biological Psychiatry.

[23]  M. Daneman,et al.  Working memory and language comprehension: A meta-analysis , 1996, Psychonomic bulletin & review.

[24]  J. Cohen,et al.  Context-processing deficits in schizophrenia: converging evidence from three theoretically motivated cognitive tasks. , 1999, Journal of abnormal psychology.