1, 2, 3-Triazoles: scaffold with medicinal significance

Despite a significant work on 1,2,3-triazoles, continuous efforts are still being made to identify novel heterocyclic compounds with potent bioactivities. This review may help the medicinal chemists to develop new leads possessing 1,2,3-triazoles nucleus with higher efficacy. This review throws light on the detailed synthetic approaches which have been used for the synthesis of triazoles since the early development in the area of triazole chemistry. This has been followed by the in depth analysis of the triazoles with respect to their medicinal significance.

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