The comet assay: a comprehensive review.
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[1] A. Waugh,et al. Effect of diet and vitamin C on DNA strand breakage in freshly-isolated human white blood cells. , 1994, Mutation research.
[2] M. Green,et al. UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: a potential diagnostic technique. , 1992, Mutation research.
[3] H. H. Evans,et al. Etoposide sensitivity and topoisomerase II activity in Chinese hamster V79 monolayers and small spheroids. , 1991, International journal of radiation biology.
[4] P. Schmezer,et al. Tissue-specific induction of mutations by streptozotocin in vivo. , 1994, Mutation research.
[5] H. Okamoto,et al. Detection of carcinogen-induced DNA breaks by nick translation in permeable cells. , 1983, Biochemical and biophysical research communications.
[6] Vijayalaxmi,et al. Assessment of radiation-induced DNA damage in human blood lymphocytes using the single-cell gel electrophoresis technique. , 1992, Mutation research.
[7] J. Brown,et al. SR 4233 (tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours. , 1993, British Journal of Cancer.
[8] R E Durand,et al. Detection of hypoxic cells in a murine tumor with the use of the comet assay. , 1992, Journal of the National Cancer Institute.
[9] B. Nagarajan,et al. Induction of genotoxicity by salted deep-fried fish and mutton. , 1994, Mutation research.
[10] Fairbairn Dw,et al. The effect of electromagnetic field exposure on the formation of DNA single strand breaks in human cells. , 1994 .
[11] P. Olive,et al. Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay. , 1993, Radiation research.
[12] G. Duménil,et al. Genotoxic activity of potassium permanganate in acidic solutions. , 1991, Mutation research.
[13] G. Ahnström. Techniques to measure DNA single-strand breaks in cells: a review. , 1988, International journal of radiation biology.
[14] P. Schmezer,et al. Antigenotoxic properties of lactic acid bacteria in vivo in the gastrointestinal tract of rats. , 1993, Nutrition and cancer.
[15] I. Stratford,et al. The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action. , 1986, British Journal of Cancer.
[16] R. Tice,et al. A simple technique for quantitation of low levels of DNA damage in individual cells. , 1988, Experimental cell research.
[17] A. Collins,et al. Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. , 1993, Carcinogenesis.
[18] R. Klein,et al. Assessment of genotoxic effects by lindane. , 1993, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[19] R. Tyrrell,et al. The spectrum of mutations generated by passage of a hydrogen peroxide damaged shuttle vector plasmid through a mammalian host. , 1989, Nucleic acids research.
[20] K. O’Neill,et al. Detection of DNA damaging agents in environmental water samples , 1994, Bulletin of environmental contamination and toxicology.
[21] K. Greulich,et al. UV-B-laser-induced DNA damage in lymphocytes observed by single-cell gel electrophoresis. , 1994, Journal of photochemistry and photobiology. B, Biology.
[22] A. Hara,et al. Radiosensitization and inhibition of deoxyribonucleic acid repair in rat glioma cells by long-term treatment with 12-O-tetradecanoylphorbol 13-acetate. , 1993, Neurosurgery.
[23] G. Speit,et al. Comparative investigations of the genotoxic effects of metals in the single cell gel (SCG) assay and the sister chromatid exchange (SCE) test , 1994, Environmental and molecular mutagenesis.
[24] G. R. Holyoak,et al. Detection of apoptosis induced DNA cleavage in scrapie-infected sheep brain. , 1994, FEMS microbiology letters.
[25] R. Barale,et al. Comparative studies on cytotoxic and genotoxic effects of two organic mercury compounds in lymphocytes and gastric mucosa cells of sprague‐dawley rats , 1993, Environmental and molecular mutagenesis.
[26] A. Whetton,et al. Induction of apoptosis--new targets for cancer chemotherapy. , 1992, Seminars in cancer biology.
[27] M. Akashi,et al. Radiosensitivity of CD45RO+ memory and CD45RO- naive T cells in culture. , 2010, Radiation research.
[28] R. Tice,et al. Basal DNA damage in individual human lymphocytes with age. , 1991, Mutation research.
[29] M. Rosin,et al. A sensitivity to oxidative stress is linked to chromosome 11 but is not due to a difference in single strand DNA breakage or repair. , 1993, Mutation research.
[30] D. Rampton,et al. Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease. , 1992, Gastroenterology.
[31] H. H. Evans,et al. Cell killing and DNA damage by etoposide in Chinese hamster V79 monolayers and spheroids: influence of growth kinetics, growth environment and DNA packaging. , 1993, British journal of cancer.
[32] K. O’Neill,et al. Alkali-labile sites are prevalent in kidney tissue DNA. , 1994, Cancer letters.
[33] R. Williams,et al. Reconstruction in vivo of Irradiated Escherichia coli Deoxyribonucleic Acid; the Rejoining of Broken Pieces , 1966, Nature.
[34] H. Weintraub,et al. Transcription of DNA injected into Xenopus oocytes is influenced by template topology , 1983, Nature.
[35] U. Plappert,et al. Does physical activity induce DNA damage? , 1994, Mutagenesis.
[36] A. Wyllie,et al. Apoptosis. The role of the endonuclease. , 1990, The American journal of pathology.
[37] R. Tice,et al. The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. , 1991, Advances in experimental medicine and biology.
[38] B. Rydberg. Detection of DNA strand breaks in single cells using flow cytometry. , 1984, International journal of radiation biology and related studies in physics, chemistry, and medicine.
[39] P. Smith,et al. Simultaneous measurement of cell cycle phase position and ionizing radiation-induced DNA strand breakage in single human tumour cells using laser scanning confocal imaging. , 1992, International journal of radiation biology.
[40] A. Wyllie,et al. Macrophage recognition of cells undergoing programmed cell death (apoptosis). , 1985, Immunology.
[41] Jackson,et al. Growth Fraction of Human Tumors: Assays and Complications. , 1993, Seminars in radiation oncology.
[42] A. Wyllie,et al. Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis. , 1984, The American journal of pathology.
[43] B. Rydberg,et al. ESTIMATION OF DNA STRAND BREAKS IN SINGLE MAMMALIAN CELLS , 1978 .
[44] R. Tyrrell,et al. Mutagenesis by hydrogen peroxide treatment of mammalian cells: a molecular analysis. , 1990, Carcinogenesis.
[45] K. O’Neill,et al. Analysis of single-cell gel electrophoresis using laser-scanning microscopy. , 1993, Mutation research.
[46] R R Tice,et al. The single cell gel assay: a sensitive technique for evaluating intercellular differences in DNA damage and repair. , 1990, Basic life sciences.
[47] F. Ramsdell,et al. Fas transduces activation signals in normal human T lymphocytes , 1993, The Journal of experimental medicine.
[48] S. Linn,et al. Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro. , 1988, Science.
[49] A. Lehmann,et al. Double-strand breaks in the DNA of a mammalian cell after x-irradiation. , 1970, Biochimica et biophysica acta.
[50] T. McMillan,et al. 1st L. H. Gray Workshop. Measurement of radiation-induced damage. , 1990, International journal of radiation biology.
[51] R R Tice,et al. Abundant alkali-sensitive sites in DNA of human and mouse sperm. , 1989, Experimental cell research.
[52] R. Everson,et al. Measuring DNA damage in individual cells of heterogeneous mixtures: a novel application of an immunological typing technique. , 1994, Mutation research.
[53] M. Kruszewski,et al. DNA strand breakage, cytotoxicity and mutagenicity of hydrogen peroxide treatment at 4°C and 37°C in L5178Y sublines , 1994 .
[54] K. O’Neill,et al. Laser scanning microscopic analysis of DNA damage in frozen tissues. , 1994, Cancer letters.
[55] Vijayalaxmi,et al. An analysis of γ-ray-induced DNA damage in human blood leukocytes, lymphocytes and granulocytes , 1993 .
[56] K J Johanson,et al. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. , 1984, Biochemical and biophysical research communications.
[57] D. Bredesen,et al. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. , 1993, Science.
[58] A. Collins,et al. Single-cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells. , 1992, International journal of radiation biology.
[59] H. Langemann,et al. Investigation of the repair of single-strand breaks in human DNA using alkaline gel electrophoresis. , 1990, Radiation research.
[60] J. Ashby,et al. Genotoxic activity of 1-chloromethylpyrene in stomach epithelium in vivo: insensitivity of the stomach scintillation UDS assay. , 1993, Carcinogenesis.
[61] X. M. Sun,et al. Characterization of apoptosis in thymocytes isolated from dexamethasone-treated rats. , 1992, Biochemical pharmacology.
[62] K. Johanson,et al. Bleomycin, in contrast to gamma irradiation, induces extreme variation of DNA strand breakage from cell to cell. , 1987, International journal of radiation biology and related studies in physics, chemistry, and medicine.
[63] N. Singh,et al. Modifications of alkaline microgel electrophoresis for sensitive detection of DNA damage. , 1994, International journal of radiation biology.
[64] D. Vaux. Toward an understanding of the molecular mechanisms of physiological cell death. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[65] Gwyn T. Williams. Programmed cell death: Apoptosis and oncogenesis , 1991, Cell.
[66] J C Sutherland,et al. Quantitation of radiation-, chemical-, or enzyme-induced single strand breaks in nonradioactive DNA by alkaline gel electrophoresis: application to pyrimidine dimers. , 1986, Analytical biochemistry.
[67] C. V. Barber,et al. The role of oxygenation in embryotoxic mechanisms of three bioreducible agents. , 1993, Teratology.
[68] J. Lewis,et al. The effect of macrophage development on the release of reactive oxygen intermediates and lipid oxidation products, and their ability to induce oxidative DNA damage in mammalian cells. , 1986, Carcinogenesis.
[69] P. Cook,et al. Supercoils in human DNA. , 1975, Journal of cell science.
[70] K. Guyton,et al. Oxidative mechanisms in carcinogenesis. , 1993, British medical bulletin.
[71] J. Cunningham,et al. Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage: relation to nitric oxide production. , 1994, Biochemical Society transactions.
[72] K. O’Neill,et al. Application of confocal laser scanning microscopy to analysis of H2O2-induced DNA damage in human cells. , 1993, Scanning.
[73] W. Dalton,et al. Gene-specific DNA interstrand cross-links produced by nitrogen mustard in the human tumor cell line Colo320HSR. , 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[74] P. Hanawalt,et al. DNA repair : a laboratory manual of research procedures , 1981 .
[75] B L Diffey,et al. Hypersensitivity of human lymphocytes to UV-B and solar irradiation. , 1993, Cancer research.
[76] P. Olive,et al. Induction and rejoining of radiation-induced DNA single-strand breaks: "tail moment" as a function of position in the cell cycle. , 1993, Mutation research.
[77] I. Olivotto,et al. Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers. , 1993, Cancer research.
[78] P. Olive. DNA organization affects cellular radiosensitivity and detection of initial DNA strand breaks. , 1992, International journal of radiation biology.
[79] J. A. Allen,et al. Induction of DNA damage by low level laser irradiation in Friend mouse erythroleukaemia cells , 1992 .
[80] P. Olive,et al. Response of fibroblast cultures from ataxia‐telangiectasia patients to reactive oxygen species generated during inflammatory reactions , 1994, Environmental and molecular mutagenesis.
[81] B. Vogelstein,et al. Supercoiled loops and eucaryotic DNA replication , 1980, Cell.
[82] A. Hara,et al. A single cell gel electrophoresis technique for the detection of DNA damage induced by ACNU, an alkylating agent or irradiation in murine glioma cell lines. , 1994, Neurological research.
[83] P. Cerutti. Prooxidant states and tumor promotion. , 1985, Science.
[84] M. Berardini,et al. Electrophoretic and chromatographic separation methods used to reveal interstrand crosslinking of nucleic acids. , 1993, Journal of chromatography.
[85] P. Olive,et al. Growth fraction measured using the comet assay , 1992, Cell proliferation.
[86] D. Schwartz,et al. Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis , 1984, Cell.
[87] P. Olive. Radiation-induced reoxygenation in the SCCVII murine tumour: evidence for a decrease in oxygen consumption and an increase in tumour perfusion. , 1994, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
[88] W Böcker,et al. Comet assay studies of radiation-induced DNA damage and repair in various tumour cell lines. , 1994, International journal of radiation biology.
[89] K. Kohn,et al. X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. , 1979, Nucleic acids research.
[90] George Lliakis,et al. The role of DNA double strand breaks in lonizing radiation‐induced killing of eukaryotic cells , 1991 .
[91] M. Berardini,et al. Effect of linker length on DNA-binding affinity, cross-linking efficiency and cytotoxicity of C8-linked pyrrolobenzodiazepine dimers , 1992 .
[92] P. Olive,et al. Cell proliferation as a requirement for development of the contact effect in Chinese hamster V79 spheroids. , 1989, Radiation research.
[93] G. Felsenfeld,et al. Chromatin as an essential part of the transcriptional mechanim , 1992, Nature.
[94] P. Olive,et al. DNA double-strand break rejoining deficiency in TK6 and other human B-lymphoblast cell lines. , 1993, Radiation research.
[95] B. Fertil,et al. Detection in situ of gamma-ray-induced DNA strand breaks in single cells: enzymatic labelling of free 3'-OH ends. , 1984, International journal of radiation biology and related studies in physics, chemistry, and medicine.
[96] E. A. Martins,et al. Role of antioxidants in protecting cellular DNA from damage by oxidative stress. , 1991, Mutation research.
[97] A. Spector,et al. DNA single strand breaks in human lens epithelial cells from patients with cataract. , 1993, Current eye research.
[98] P. Olive,et al. Comparison between the DNA precipitation and alkali unwinding assays for detecting DNA strand breaks and cross-links. , 1988, Cancer research.
[99] T. Slater,et al. An introduction to free radical biochemistry. , 1993, British medical bulletin.
[100] A. Falek,et al. Detection of opiate‐enhanced increases in DNA damage, HPRT mutants, and the mutation frequency in human HUT‐78 cells , 1994, Environmental and molecular mutagenesis.
[101] R. Jostes,et al. Single-cell gel technique supports hit probability calculations. , 1993, Health physics.
[102] M. Green,et al. Endogenous nitric oxide induced by interleukin‐1β in rat islets of Langerhans and HIT‐T15 cells causes significant DNA damage as measured by the ‘comet’ assay , 1993, FEBS letters.
[103] K. Frenkel. Carcinogen-mediated oxidant formation and oxidative DNA damage. , 1992, Pharmacology & therapeutics.
[104] R. Tice,et al. High-dose combination alkylating agents with autologous bone-marrow support in patients with breast cancer: preliminary assessment of DNA damage in individual peripheral blood lymphocytes using the single cell gel electrophoresis assay. , 1992, Mutation research.
[105] B. Ames,et al. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. , 1983, Science.
[106] J. T. Kadonaga,et al. Role of chromatin structure in the regulation of transcription by RNA polymerase II. , 1993, Current opinion in cell biology.
[107] P. Olive,et al. Hypoxic fractions measured in murine tumors and normal tissues using the comet assay. , 1994, International journal of radiation oncology, biology, physics.
[108] J. R. Roti Roti,et al. Visualization of DNA loops in nucleoids from HeLa cells: assays for DNA damage and repair. , 1987, Cytometry.
[109] Y. Higami,et al. An age-related increase in the basal level of DNA damage and DNA vulnerability to oxygen radicals in the individual hepatocytes of male F344 rats. , 1994, Mutation research.
[110] B. Vogelstein,et al. A genetic model for colorectal tumorigenesis , 1990, Cell.
[111] S. Linn,et al. DNA damage and oxygen radical toxicity. , 1988, Science.
[112] Meyers Cd,et al. Measuring the repair of H2O2-induced DNA single strand breaks using the single cell gel assay. , 1993 .
[113] R R Tice,et al. DNA damage and repair with age in individual human lymphocytes. , 1990, Mutation research.
[114] R. Barale,et al. Microgel electrophoresis assay (comet test) and SCE analysis in human lymphocytes from 100 normal subjects. , 1994, Mutation research.
[115] P. Schmezer,et al. The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay. , 1994, Mutation research.
[116] K. O’Neill,et al. Differential DNA damage detected in hybridomas. , 1993, Hybridoma.
[117] P. Correa,et al. Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. , 1992, Cancer research.
[118] P. Olive,et al. Detection of DNA double-strand breaks through the cell cycle after exposure to X-rays, bleomycin, etoposide and 125IdUrd. , 1993, International journal of radiation biology.
[119] P. Olive,et al. Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells. , 1990, Journal of the National Cancer Institute.
[120] R R Tice,et al. A microgel electrophoresis technique for the direct quantitation of DNA damage and repair in individual fibroblasts cultured on microscope slides. , 1991, Mutation research.
[121] A. Waugh,et al. Effect of deoxyribonucleosides on the hypersensitivity of human peripheral blood lymphocytes to UV-B and UV-C irradiation. , 1994, Mutation research.
[122] S. Powell,et al. Molecular assays of radiation-induced DNA damage. , 1991, European Journal of Cancer.
[123] C. Fjell,et al. DNA strand breakage and DNA structure influence staining with propidium iodide using the alkaline comet assay. , 1994, Cytometry.
[124] P. Olive,et al. DNA double-strand breaks measured in individual cells subjected to gel electrophoresis. , 1991, Cancer research.
[125] R E Durand,et al. Factors influencing DNA migration from individual cells subjected to gel electrophoresis. , 1992, Experimental cell research.
[126] W. Dewey,et al. Calibration of pulsed field gel electrophoresis for measurement of DNA double-strand breaks. , 1990, International journal of radiation biology.
[127] M. Green,et al. The single cell gel electrophoresis assay (comet assay): a European review. , 1993, Mutation research.
[128] P. Schmezer,et al. Detection of genotoxic effects in human gastric and nasal mucosa cells isolated from biopsy samples , 1994, Environmental and molecular mutagenesis.
[129] G. Ahnström,et al. Letter: Radiation-induced single-strand breaks in DNA determined by rate of alkaline strand separation and hydroxylapatite chromatography: an alternative to velocity sedimentation. , 1974, International journal of radiation biology and related studies in physics, chemistry, and medicine.
[130] B. Nordén,et al. Microscopic behaviour of DNA during electrophoresis: electrophoretic orientation , 1991, Quarterly Reviews of Biophysics.