Inhibition of DNA synthesis by somatostatin in rat hepatocytes stimulated by hepatocyte growth factor or epidermal growth factor.

[1]  S. Raper,et al.  Inhibitory effects of somatostatin on rat hepatocyte proliferation are mediated by cyclic AMP. , 1991, The Journal of surgical research.

[2]  S. Raper,et al.  Somatostatin-14 blocks the hepatotrophic effects of insulin in the rat. , 1991, The Journal of surgical research.

[3]  J. Rubin,et al.  A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[4]  A. Moses,et al.  Somatostatin inhibits deoxyribonucleic acid synthesis induced by both thyrotropin and insulin-like growth factor-I in FRTL5 cells. , 1990, Endocrinology.

[5]  K. Tashiro,et al.  Molecular cloning and expression of human hepatocyte growth factor , 1989, Nature.

[6]  P. Månsson,et al.  Heparin-binding growth factor type 1 (acidic fibroblast growth factor): a potential biphasic autocrine and paracrine regulator of hepatocyte regeneration. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[7]  H. Earp,et al.  The epidermal growth factor receptor tyrosine kinase in liver epithelial cells. The effect of ligand-dependent changes in cellular location. , 1989, The Journal of biological chemistry.

[8]  R. Coffey,et al.  Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[9]  L. Agius,et al.  Epidermal growth factor counteracts the glycogenic effect of insulin in parenchymal hepatocyte cultures. , 1987, Biochemical Journal.

[10]  A. Schally,et al.  Immunomodulatory Action of Somatostatin , 1987, Annals of the New York Academy of Sciences.

[11]  J. Maher,et al.  Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver. , 1987, The Journal of clinical investigation.

[12]  T. Nakamura,et al.  Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[13]  H. Moses,et al.  Inhibition of DNA Synthesis in rat hepatocytes by Platelet-derived Type β Transforming Growth Factor , 1986 .

[14]  A. Schonbrunn,et al.  Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium. , 1985, The Journal of biological chemistry.

[15]  J. Morisset Somatostatin: a potential antigrowth factor for the exocrine pancreas , 1984, Regulatory Peptides.

[16]  J. Schlessinger,et al.  Biologically active synthetic fragments of epidermal growth factor: localization of a major receptor-binding region. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[17]  F. Iber Hepatology: A Textbook of Liver Disease , 1983 .

[18]  B. Langer,et al.  The effect of liver cytosol on hepatic regeneration and tumor growth , 1983, Cancer.

[19]  R. Mascardo,et al.  Somatostatin inhibits rapid centrosomal separation and cell proliferation induced by epidermal growth factor. , 1982, Endocrinology.

[20]  N. Bucher,et al.  DNA synthesis in primary cultures of adult rat hepatocytes in a defined medium: Effects of epidermal growth factor, insulin, glucagon, and cyclic‐AMP , 1981, Journal of cellular physiology.

[21]  T. Wheatley,et al.  A sensitive radioimmunoassay for immunoreactive somatostatin in extracted plasma: measurement and characterization of portal and peripheral plasma in the rat. , 1980, Endocrinology.

[22]  G. Stark,et al.  Transfer of proteins from gels to diazobenzyloxymethyl-paper and detection with antisera: a method for studying antibody specificity and antigen structure. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[23]  T. Matsumura,et al.  Tissue dispersion, cell harvest and fluid suspension culture by the use of bacterial neutral protease. , 1975, The Japanese journal of experimental medicine.

[24]  H. Otsuka,et al.  Inhibition of DNA synthesis in ascites hepatoma cells by normal liver extract. , 1966, Biochimica et biophysica acta.

[25]  S. Raper,et al.  The liver plays an important role in the regulation of somatostatin-14 in the rat. , 1991, American journal of surgery.

[26]  S. Reichlin Somatostatin (First of two parts) , 1983 .

[27]  T. Lehy,et al.  Effect of somatostatin on normal and gastric-stimulated cell proliferation in the gastric and intestinal mucosae of the rat. , 1979, Digestion.

[28]  P. Seglen Preparation of isolated rat liver cells. , 1976, Methods in cell biology.

[29]  E. Volkin,et al.  Estimation of nucleic acids. , 1954, Methods of biochemical analysis.

[30]  R. Anderson,et al.  Experimental pathology of liver: restoration of liver in white rat following partial surgical removal , 1931 .

[31]  G. Higgins,et al.  Experimental pathology of the liver , 1931 .