TNF‐α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury

Acute kidney injury (AKI) is a common complication of acute liver failure (ALF). Pyroptosis is a necrosis type related to inflammation. This study aimed to investigate the role of TNF‐α/HMGB1 pathway in pyroptosis during ALF and AKI.

[1]  D. Muruve,et al.  NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways. , 2019, Archives of biochemistry and biophysics.

[2]  R. Wiesner,et al.  Simultaneous liver kidney transplantation , 2019, Transplant international : official journal of the European Society for Organ Transplantation.

[3]  Hong Zhang,et al.  Effects of A94T and P84L Polymorphisms Within the TNF-α Gene on Proliferation and Activation of Hepatic Stellate Cells. , 2019, DNA and cell biology.

[4]  P. Wang,et al.  ADP-heptose: A new innate immune modulator. , 2019, Carbohydrate research.

[5]  X. Xia,et al.  What role does pyroptosis play in microbial infection? , 2018, Journal of cellular physiology.

[6]  A. Bhatti,et al.  Lack of association of –863C/A (rs1800630) polymorphism of tumor necrosis factor-a gene with rheumatoid arthritis , 2018, Archives of medical science : AMS.

[7]  Jun Zhang,et al.  The Effect and Mechanism of TLR9/KLF4 in FFA-Induced Adipocyte Inflammation , 2018, Mediators of inflammation.

[8]  M. Saleh,et al.  An updated view on the functions of caspases in inflammation and immunity. , 2018, Seminars in cell & developmental biology.

[9]  W. Mitchell,et al.  Caspase-1 and Caspase-11 Mediate Pyroptosis, Inflammation, and Control of Brucella Joint Infection , 2018, Infection and Immunity.

[10]  M. Rizk,et al.  Association of Tumor Necrosis Factor Alpha-Induced Protein 3 Interacting Protein 1 (TNIP1) Gene Polymorphism (rs7708392) with Lupus Nephritis in Egyptian Patients , 2018, Biochemical Genetics.

[11]  Hui Chen,et al.  The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway , 2018, Mediators of inflammation.

[12]  E. Ponomarev,et al.  Cyclic AMP Pathway Suppress Autoimmune Neuroinflammation by Inhibiting Functions of Encephalitogenic CD4 T Cells and Enhancing M2 Macrophage Polarization at the Site of Inflammation , 2018, Front. Immunol..

[13]  K. Dev,et al.  Macrophages: Their role, activation and polarization in pulmonary diseases , 2017, Immunobiology.

[14]  J. Cavaillon Exotoxins and endotoxins: Inducers of inflammatory cytokines. , 2017, Toxicon : official journal of the International Society on Toxinology.

[15]  A. Davenport,et al.  Acute kidney injury in acute-on-chronic liver failure: where does hepatorenal syndrome fit? , 2017, Kidney international.

[16]  S. Kul,et al.  TNF-α and IL-1 β Cytokine Gene Polymorphism in Patients with Nasal Polyposis. , 2017, Turkish archives of otorhinolaryngology.

[17]  Fan Yang,et al.  Role of histone deacetylase expression levels and activity in the inflammatory responses of patients with chronic hepatitis B. , 2017, Molecular medicine reports.

[18]  S. de Seigneux,et al.  Preventing the Progression of AKI to CKD: The Role of Mitochondria. , 2017, Journal of the American Society of Nephrology : JASN.

[19]  B. Liu,et al.  The pattern recognition receptor, Mincle, is essential for maintaining the M1 macrophage phenotype in acute renal inflammation. , 2017, Kidney international.

[20]  Y. Huang,et al.  TNF-α-induced LRG1 promotes angiogenesis and mesenchymal stem cell migration in the subchondral bone during osteoarthritis , 2017, Cell Death and Disease.

[21]  Yi-zhen Wang,et al.  Iron Reduces M1 Macrophage Polarization in RAW264.7 Macrophages Associated with Inhibition of STAT1 , 2017, Mediators of inflammation.

[22]  G. Núñez,et al.  Mechanism and Regulation of NLRP3 Inflammasome Activation. , 2016, Trends in biochemical sciences.

[23]  I. Tzeng,et al.  Systemic inflammatory response syndrome is more associated with bacteremia in elderly patients with suspected sepsis in emergency departments , 2016, Medicine.

[24]  R. Formica Simultaneous liver kidney transplantation , 2016, Current opinion in nephrology and hypertension.

[25]  Richard Moreau,et al.  Systemic inflammation in decompensated cirrhosis: Characterization and role in acute‐on‐chronic liver failure , 2016, Hepatology.

[26]  Scott P. Campbell,et al.  A phased strategy to differentiate human CD14+monocytes into classically and alternatively activated macrophages and dendritic cells. , 2016, BioTechniques.

[27]  G. Szabo,et al.  Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease. , 2016, World journal of gastroenterology.

[28]  F. Tinti,et al.  Recent advances in pathophysiology and biomarkers of sepsis-induced acute kidney injury. , 2016, The Journal of infection.

[29]  F. Durand,et al.  Pathogenesis of Hepatorenal Syndrome: Implications for Therapy. , 2016, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[30]  M. Maes,et al.  Experimental models of hepatotoxicity related to acute liver failure. , 2016, Toxicology and applied pharmacology.

[31]  S. Sarin,et al.  Acute kidney injury in acute on chronic liver failure , 2016, Hepatology International.

[32]  R. Moreau,et al.  Mechanisms of decompensation and organ failure in cirrhosis: From peripheral arterial vasodilation to systemic inflammation hypothesis. , 2015, Journal of hepatology.

[33]  M. Stayoussef,et al.  The relationship between TNF alpha gene polymorphisms (-238/-308), TNF RII VNTR (p75) and outcomes of hepatitis B virus infection in Tunisian population. , 2015, Gene.

[34]  M. Raes,et al.  M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide , 2015, BMC Cancer.

[35]  P. Allavena,et al.  Macrophage polarization in pathology , 2015, Cellular and Molecular Life Sciences.

[36]  William M. Lee,et al.  Risk factors and outcomes of acute kidney injury in patients with acute liver failure. , 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[37]  B. Dabhi,et al.  In silico analysis of single nucleotide polymorphism (SNP) in human TNF-α gene , 2014, Meta gene.

[38]  Z. Dong,et al.  Regulated cell death in AKI. , 2014, Journal of the American Society of Nephrology : JASN.

[39]  A. Linkermann,et al.  The fire within: pyroptosis in the kidney. , 2014, American journal of physiology. Renal physiology.

[40]  J. Kellum,et al.  A Unified Theory of Sepsis-Induced Acute Kidney Injury: Inflammation, Microcirculatory Dysfunction, Bioenergetics, and the Tubular Cell Adaptation to Injury , 2014, Shock.

[41]  H. Anders,et al.  Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis. , 2014, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[42]  R. Squitti,et al.  In silico investigation of the ATP7B gene: insights from functional prediction of non-synonymous substitution to protein structure , 2013, BioMetals.

[43]  M. Pavesi,et al.  Prognostic importance of the cause of renal failure in patients with cirrhosis. , 2011, Gastroenterology.

[44]  Youliang Wang,et al.  Targeted expression of uncoupling protein 2 to mouse liver increases the susceptibility to lipopolysaccharide/galactosamine‐induced acute liver injury , 2009, Hepatology.

[45]  P. Hayes,et al.  The systemic inflammatory response syndrome is predictive of renal dysfunction in patients with non-paracetamol-induced acute liver failure , 2008, Gut.

[46]  M. Saleh,et al.  Cell death in the host response to infection , 2008, Cell Death and Differentiation.

[47]  T. Ottenhoff,et al.  Is there a future for TNF promoter polymorphisms? , 2004, Genes and Immunity.

[48]  B. Cookson,et al.  Pro-inflammatory programmed cell death. , 2001, Trends in microbiology.

[49]  K. Böker,et al.  Akutes Leberversagen , 2001, Der Internist.

[50]  M. Matsuoka,et al.  Polymorphism of the 5'-flanking region of the tumor necrosis factor (TNF)-alpha gene and susceptibility to human T-cell lymphotropic virus type I (HTLV-I) uveitis. , 1999, The Journal of infectious diseases.

[51]  Gilla Kaplan,et al.  Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production , 1999 .

[52]  G. Kaplan,et al.  Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. , 1999, Bioorganic & medicinal chemistry letters.

[53]  D. Hartl,et al.  Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter. , 1998, Tissue antigens.

[54]  J. Belaiche,et al.  Tumour necrosis factor (TNF) gene polymorphism influences TNF‐α production in lipopolysaccharide (LPS)‐stimulated whole blood cell culture in healthy humans , 1998, Clinical and experimental immunology.

[55]  H. Mcdevitt,et al.  Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.