Initial experience with laparoscopic posterior retroperitoneal adrenalectomy in single tertiary center

Purpose Laparoscopic posterior retroperitoneal adrenalectomy (LPRA) is a surgical method that accesses the adrenal gland through the back. The aim of this study was to report initial experience of LPRA and evaluate possibilities for surgical application. Methods From March 2018 to December 2019, a total of 30 consecutive patients diagnosed with adrenal tumor underwent surgical treatment at Pusan National University Hospital were enrolled. Clinicopathologic features and various peri- and postoperative parameters were analyzed by retrospective medical record review. The mean age of the patients was 48.20±13.66 years. Results The mean body mass index (BMI) was 25.50±4.30 kg/m2. Primary hyperaldosteronism was the most frequently preoperative diagnosed disease (n=13, 43.4%), followed by adrenal incidentaloma (n=8, 26.6%), Cushing syndrome (n=5, 16.6%) and pheochromocytoma (n=4, 13.3%). The mean size of postoperative adrenal tumor was 2.72±1.76 cm. The mean operating time was 162±58.14 minutes. Among the 30 patients, 28 patients underwent total adrenalectomy (93.3%) and two patients underwent cortical sparing adrenalectomy (6.7%). When LPRA was performed for patients with BMI >23.16 kg/m2, the operating time was longer than the average (P=0.016). Conclusion LPRA was suitable and safe for patients with benign adrenal tumors. BMI, retroperitoneal fat density and postoperative adrenal weight may be related to the operating time, so they should be considered when deciding on a surgical method for adrenalectomy.

[1]  I. B. Borel Rinkes,et al.  Laparoscopic anterior versus endoscopic posterior approach for adrenalectomy: a shift to a new golden standard? , 2016, Langenbeck's Archives of Surgery.

[2]  P. Touska,et al.  Retroperitoneoscopic or laparoscopic adrenalectomy? A single-centre UK experience , 2013, Surgical Endoscopy.

[3]  A. Mehdizadeh,et al.  Comparison of transperitoneal versus retroperitoneal laparoscopic adrenalectomy in a prospective randomized study. , 2013, Journal of laparoendoscopic & advanced surgical techniques. Part A.

[4]  E. Berber,et al.  Laparoscopic posterior retroperitoneal adrenalectomy , 2012, Journal of surgical oncology.

[5]  K. Economopoulos,et al.  Impact of posterior retroperitoneoscopic adrenalectomy in a tertiary care center: a paradigm shift , 2011, Surgical Endoscopy.

[6]  G. Valk,et al.  Retroperitoneal endoscopic adrenalectomy is safe and effective , 2010, The British journal of surgery.

[7]  H. Bonjer,et al.  Endoscopic retroperitoneal adrenalectomy , 1999, Acta Chirurgica Austriaca.

[8]  Anastasios Deligiannis,et al.  Posterior retroperitoneoscopic adrenalectomy--results of 560 procedures in 520 patients. , 2006, Surgery.

[9]  M. Barczyński,et al.  Posterior Retroperitoneoscopic Adrenalectomy: A Comparison between the Initial Experience in the Invention Phase and Introductory Phase of the New Surgical Technique , 2006, World Journal of Surgery.

[10]  S. Ozono,et al.  Laparoscopic adrenalectomy for large adrenal tumors. , 2005, Journal of endourology.

[11]  J. Kaouk,et al.  Prospective, randomized comparison of transperitoneal versus retroperitoneal laparoscopic adrenalectomy. , 2005, The Journal of urology.

[12]  E. Kebebew,et al.  Laparoscopic adrenalectomy for malignancy. , 2004, The Surgical clinics of North America.

[13]  G. Cavallaro,et al.  Expectations and Outcomes When Moving from Open to Laparoscopic Adrenalectomy: Multivariate Analysis , 2003, World Journal of Surgery.

[14]  T. Nishikawa,et al.  Laparoscopic adrenalectomy: comparison of transperitoneal and retroperitoneal approaches , 2002, BJU international.

[15]  E. Higashihara,et al.  Laparoscopic adrenalectomy: Alternative or new standard? , 2002, Current urology reports.

[16]  C. D. Smith,et al.  Laparoscopic Adrenalectomy: New Gold Standard , 1999, World Journal of Surgery.

[17]  M. Talamini,et al.  Laparoscopic adrenalectomy for nonmalignant disease: improved safety, morbidity, and cost-effectiveness , 1999, Surgical Endoscopy.

[18]  S. Migliori,et al.  Laparoscopic adrenalectomy for benign adrenal neoplasms , 1999, Surgical Endoscopy.

[19]  L. Kavoussi,et al.  Laparoscopic adrenalectomy: a new standard of care. , 1997, Urology.

[20]  T. Fahey,et al.  Adrenalectomy: expanded indications for the extraperitoneal approach. , 1994, The Australian and New Zealand journal of surgery.

[21]  C. Proye,et al.  Safety of the posterior approach in adrenal surgery: experience in 105 cases. , 1993, Surgery.

[22]  M. Gagner,et al.  Laparoscopic adrenalectomy in Cushing's syndrome and pheochromocytoma. , 1992, The New England journal of medicine.