Design and Synthesis of a MAO‐B‐Selectively Activated Prodrug Based on MPTP: A Mitochondria‐Targeting Chemotherapeutic Agent for Treatment of Human Malignant Gliomas
暂无分享,去创建一个
David S Baskin | Junyan Han | D. Baskin | Junyan Han | Martyn A Sharpe | M. Sharpe | Alexandra M Baskin | Alexandra M. Baskin
[1] R. M. Rose,et al. Distinct monoamine oxidase A and B populations in primate brain. , 1985, Science.
[2] Edward Chu,et al. A history of cancer chemotherapy. , 2008, Cancer research.
[3] L. Callado,et al. Monoamine oxidase B activity is increased in human gliomas , 2008, Neurochemistry International.
[4] K. Chan,et al. Kinetics of phosphoramide mustard hydrolysis in aqueous solution. , 1985, Journal of pharmaceutical sciences.
[5] C. Franceschi,et al. JC‐1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess ΔΨ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis , 1997, FEBS letters.
[6] J. Finberg. Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: focus on modulation of CNS monoamine neurotransmitter release. , 2014, Pharmacology & therapeutics.
[7] T. Roszman,et al. Suppression of high affinity IL-2 receptors on mitogen activated lymphocytes by glioma-derived suppressor factor , 1992, Journal of Neuro-Oncology.
[8] G. Engberg,et al. Deprenyl (selegiline), a selective MAO-B inhibitor with active metabolites; effects on locomotor activity, dopaminergic neurotransmission and firing rate of nigral dopamine neurons. , 1991, The Journal of pharmacology and experimental therapeutics.
[9] E. Niki,et al. 1‐Methyl‐4‐phenyl‐2,3‐dihydropyridinium is transformed by ubiquinone to the selective nigrostriatal toxin 1‐methyl‐4‐phenylpyridinium , 1999, FEBS letters.
[10] M. Vila,et al. Localization of monoamine oxidases in human peripheral tissues. , 1996, Life sciences.
[11] R. M. Rose,et al. Localization of distinct monoamine oxidase a and monoamine oxidase b cell populations in human brainstem , 1988, Neuroscience.
[12] P. Mander,et al. Fibrillar beta-amyloid peptide Aβ1–40 activates microglial proliferation via stimulating TNF-α release and H2O2 derived from NADPH oxidase: a cell culture study , 2006, Journal of Neuroinflammation.
[13] P. Lampen,et al. In vivo intracerebral microdialysis studies in rats of MPP+ (1-methyl-4-phenylpyridinium) analogs and related charged species , 1990 .
[14] Andrea Mattevi,et al. Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[15] C. Franceschi,et al. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1). , 1993, Biochemical and biophysical research communications.
[16] H. Pollard,et al. Contrasting monoamine oxidase activity and tyramine induced catecholamine release in PC12 and chromaffin cells , 1986, Neuroscience.
[17] Yang Zhou,et al. Optical Imaging of Tumors with Copper-Labeled Rhodamine Derivatives by Targeting Mitochondria , 2012, Theranostics.
[18] Alan A. Wilson,et al. Distribution of Monoamine Oxidase Proteins in Human Brain: Implications for Brain Imaging Studies , 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[19] L. Deangelis,et al. Glioblastoma and other malignant gliomas: a clinical review. , 2013, JAMA.
[20] J. Rey,et al. Effect of lomeguatrib–temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells , 2013, Tumor Biology.
[21] J. Villano,et al. Long-term treatment with temozolomide in malignant glioma , 2014, Journal of Clinical Neuroscience.
[22] A. Brossi,et al. Metabolism of the neurotoxin in MPTP by human liver monoamine oxidase B , 1985, FEBS letters.
[23] Eric Gouaux,et al. X-ray structure of dopamine transporter elucidates antidepressant mechanism , 2013, Nature.
[24] L. Galluzzi,et al. Mitochondria as therapeutic targets for cancer chemotherapy , 2006, Oncogene.
[25] G. Meredith,et al. MPTP mouse models of Parkinson's disease: an update. , 2011, Journal of Parkinson's disease.
[26] Andrea Mattevi,et al. Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class. , 2004, Journal of medicinal chemistry.
[27] H. Weinstein,et al. The binding sites for cocaine and dopamine in the dopamine transporter overlap , 2008, Nature Neuroscience.
[28] R. Stupp,et al. Current concepts and management of glioblastoma , 2011, Annals of neurology.
[29] R. Ramsay,et al. Substrate-specific enhancement of the oxidative half-reaction of monoamine oxidase. , 1993, Biochemistry.
[30] P. Sinko,et al. Recent trends in targeted anticancer prodrug and conjugate design. , 2008, Current medicinal chemistry.
[31] R. Haugland,et al. A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases. , 1997, Analytical biochemistry.
[32] L. Pearce,et al. Human brain monoamine oxidase: solubilization and kinetics of inhibition by octylglucoside. , 1983, Archives of biochemistry and biophysics.
[33] C. Williams. Monoamine oxidase. I. Specificity of some substrates and inhibitors. , 1974, Biochemical pharmacology.
[34] Abhigna Polavarapu,et al. The mechanism of guanine alkylation by nitrogen mustards: a computational study. , 2012, The Journal of organic chemistry.
[35] N. Freedman,et al. In vivo measurement of brain monoamine oxidase B occupancy by rasagiline, using (11)C-l-deprenyl and PET. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[36] K. Tipton,et al. Uptake and accumulation of 1-methyl-4-phenylpyridinium by rat liver mitochondria measured using an ion-selective electrode. , 1992, The Biochemical journal.
[37] N. Castagnoli,et al. Potential latent nitrogen mustard derivatives designed to target monoamine oxidase rich cells. , 1997, Bioorganic & medicinal chemistry.
[38] X. Breakefield,et al. Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[39] Erwan Bezard,et al. Modeling Parkinson's disease in primates: The MPTP model. , 2012, Cold Spring Harbor perspectives in medicine.
[40] Andrea Mattevi,et al. Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[41] F. Guengerich,et al. Metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine by Mitochondrion-targeted Cytochrome P450 2D6 , 2012, The Journal of Biological Chemistry.
[42] R. Wheelhouse,et al. Glioblastoma Multiforme Therapy and Mechanisms of Resistance , 2013, Pharmaceuticals.
[43] J. Shih,et al. Monoamine oxidase: from genes to behavior. , 1999, Annual review of neuroscience.
[44] D. Edmondson,et al. Structure-activity relationships in the oxidation of para-substituted benzylamine analogues by recombinant human liver monoamine oxidase A. , 1999, Biochemistry.