Adult toxic epidermal necrolysis with fatal staphylococcal septicemia.

Toxic epidermal necrolysis is a dramatic, easily recognized clinical event in which sheets of the upper layer of the epidermis slide off the lower layers of the skin. This sign developed in a 70-year-old man in association with a rapidly fatal staphylococcal septicemia. Although recognized in children, this association has been reported only rarely in adults. Inoculation of the isolated bacterium into newborn mice produced characteristic wrinkling. Development of this epidermolysis requires immediate antibiotic therapy. (JAMA229:425-427, 1974)

[1]  D. Feingold,et al.  Staphylococcal Scalded Skin Syndrome in an Adult , 1973 .

[2]  J. Arbuthnott,et al.  The response of hairless mice to staphylococcal epidermolytic toxin , 1973, The British journal of dermatology.

[3]  H. M. Mccallum,et al.  ACTION OF STAPHYLOCOCCAL EPIDEMOLYTIC TOXIN ON MOUSE SKIN IN ORGAN CULTURE , 1972, Journal of medical microbiology.

[4]  R. Mccloskey.  Scarlet fever and necrotizing fascitis caused by coagulase-positive hemolytic Staphylococcus aureus, phage type 85. , 1973, Annals of internal medicine.

[5]  C. Norden,et al.  Staphylococcal scalded-skin syndrome in an adult. , 1972, The New England journal of medicine.

[6]  C. Gemmell,et al.  STUDIES OF STAPHYLOCOCCAL TOXINS IN RELATION TO TOXIC EPIDERMAL NECROLYSIS (THE SCALDED SKIN SYNDROME) , 1972 .

[7]  M. D. Turner,et al.  The staphylococcal scalded-skin syndrome: isolation and partial characterization of the exfoliative toxin. , 1972, The Journal of infectious diseases.

[8]  M. Miller,et al.  Product of Staphylococcus aureus Responsible for the Scalded-Skin Syndrome , 1971, Infection and immunity.

[9]  C. Gemmell,et al.  TOXIC EPIDERMAL NECROLYSIS PRODUCED BY AN EXTRACELLULAR PRODUCT OF STAPHYLOCOCCUS AUREUS , 1971, The British journal of dermatology.

[10]  M. Melish,et al.  The staphylococcal scalded-skin syndrome. , 1970, The New England journal of medicine.

[11]  H. Dick,et al.  Outbreak of toxic epidermal necrolysis associated with staphylococci. , 1969, Lancet.

[12]  A. Lyell.  A REVIEW OF TOXIC EPIDERMAL NECROLYSIS IN BRITAIN , 1967, The British journal of dermatology.

[13]  P. Koblenzer.  Acute epidermal necrolysis (Ritter von Rittershain-Lyell). A clinicopathologic study. , 1967, Archives of dermatology.

[14]  R. Auerbach,et al.  Toxic epidermal necrolysis. Acute pemphigus. , 1960, Archives of dermatology.

[15]  A. Lyell.  TOXIC EPIDERMAL NECROLYSIS: AN ERUPTION RESEMBLING SCALDING OF THE SKIN. , 1956, The British journal of dermatology.

[16]  J. Walker,et al.  An unusual bullous eruption. , 1956, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.