Forecasting the quality of water‐suppressed 1H MR spectra based on a single‐shot water scan

To investigate whether an initial non–water‐suppressed acquisition that provides information about the signal‐to‐noise ratio (SNR) and linewidth is enough to forecast the maximally achievable final spectral quality and thus inform the operator whether the foreseen number of averages and achieved field homogeneity is adequate.

[1]  K. Behar,et al.  Analysis of macromolecule resonances in 1H NMR spectra of human brain , 1994, Magnetic resonance in medicine.

[2]  S. Provencher.  Estimation of metabolite concentrations from localized in vivo proton NMR spectra , 1993, Magnetic resonance in medicine.

[3]  V. L. Doyle,et al.  Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy , 2003, Magnetic resonance in medicine.

[4]  E Moser,et al.  Proton T 1 and T 2 relaxation times of human brain metabolites at 3 Tesla , 2001, NMR in biomedicine.

[5]  Rolf Gruetter,et al.  MR spectroscopy of the human brain with enhanced signal intensity at ultrashort echo times on a clinical platform at 3T and 7T , 2009, Magnetic resonance in medicine.

[6]  R Gruetter,et al.  Automatic, localized in Vivo adjustment of all first‐and second‐order shim coils , 1993, Magnetic resonance in medicine.

[7]  R. de Beer,et al.  Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals , 2001, Comput. Biol. Medicine.

[8]  P. Lundberg,et al.  Procedure for quantitative 1H magnetic resonance spectroscopy and tissue characterization of human brain tissue based on the use of quantitative magnetic resonance imaging , 2013, Magnetic resonance in medicine.

[9]  Rolf Gruetter,et al.  Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 T using two different approaches of modelling the macromolecule spectrum , 2009 .

[10]  D. Saunders,et al.  Discrimination of Metabolite from Lipid and Macromolecule Resonances in Cerebral Infarction in Humans Using Short Echo Proton Spectroscopy , 1997, Journal of magnetic resonance imaging : JMRI.

[11]  D. Graveron-Demilly,et al.  Time-domain quantitation of 1H short echo-time signals: background accommodation , 2004, Magnetic Resonance Materials in Physics, Biology and Medicine.

[12]  V. Govindaraju,et al.  Proton NMR chemical shifts and coupling constants for brain metabolites , 2000, NMR in biomedicine.

[13]  U Klose,et al.  Proton MR spectroscopy with metabolite-nulling reveals elevated macromolecules in acute multiple sclerosis. , 2001, Brain : a journal of neurology.

[14]  D L Rothman,et al.  Spectroscopic Assessment of Alterations in Macromolecule and Small-Molecule Metabolites in Human Brain After Stroke , 2001, Stroke.

[15]  M. Sdika,et al.  Time‐domain semi‐parametric estimation based on a metabolite basis set , 2005, NMR in biomedicine.

[16]  J Higinbotham,et al.  Use of voigt lineshape for quantification of in vivo 1H spectra , 1997, Magnetic resonance in medicine.

[17]  S. Van Huffel,et al.  MRS signal quantitation: a review of time- and frequency-domain methods. , 2008, Journal of magnetic resonance.

[18]  Wolfgang Grodd,et al.  Parameterized evaluation of macromolecules and lipids in proton MR spectroscopy of brain diseases , 2003, Magnetic resonance in medicine.

[19]  Robert Bartha,et al.  Effect of signal‐to‐noise ratio and spectral linewidth on metabolite quantification at 4 T , 2007, NMR in biomedicine.

[20]  S. Provencher.  Automatic quantitation of localized in vivo 1H spectra with LCModel , 2001, NMR in biomedicine.

[21]  Karl Young,et al.  Corrigendum: Proton NMR chemical shifts and coupling constants for brain metabolites. Govindaraju V, Young K, Maudsley AA, NMR Biomed. 2000; 13: 129–153 , 2015, NMR in biomedicine.

[22]  Johannes Bernarding,et al.  Quantitation of simulated short echo time 1H human brain spectra by LCModel and AMARES , 2004, Magnetic resonance in medicine.

[23]  R. Kreis.  Issues of spectral quality in clinical 1H‐magnetic resonance spectroscopy and a gallery of artifacts , 2004, NMR in biomedicine.

[24]  Jens Frahm,et al.  Clinical proton MR spectroscopy in central nervous system disorders. , 2013, Radiology.

[25]  D van Ormondt,et al.  Cramér–Rao bounds: an evaluation tool for quantitation , 2001, NMR in biomedicine.