The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
暂无分享,去创建一个
[1] Carol W. Greider,et al. Telomere Dysfunction Increases Mutation Rate and Genomic Instability , 2001, Cell.
[2] E. Blackburn,et al. A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[3] Margaret A. Strong,et al. Telomere dysfunction triggers developmentally regulated germ cell apoptosis. , 2001, Molecular biology of the cell.
[4] M. Cerone,et al. Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability , 2001, Oncogene.
[5] N. Marziliano,et al. Pericentromeric organization at the fusion point of mouse Robertsonian translocation chromosomes. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[6] D. Gottschling,et al. The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku , 2001, Nature Genetics.
[7] P. Finnon,et al. Short Telomeres Result in Organismal Hypersensitivity to Ionizing Radiation in Mammals , 2000, The Journal of experimental medicine.
[8] E. Blackburn,et al. Telomere states and cell fates , 2000, Nature.
[9] Peter M Lansdorp,et al. Repair of telomeric DNA prior to replicative senescence , 2000, Mechanisms of Ageing and Development.
[10] Elke Feldmann,et al. DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining , 2000, Nucleic Acids Res..
[11] C. Schmoor,et al. Accumulation of short telomeres in human fibroblasts prior to replicative senescence. , 2000, Experimental Cell Research.
[12] Heidi S. Liss,et al. Subsenescent Telomere Lengths in Fibroblasts Immortalized by Limiting Amounts of Telomerase* , 2000, The Journal of Biological Chemistry.
[13] M. Hemann,et al. Telomere length, telomere-binding proteins, and DNA damage signaling. , 2000, Cold Spring Harbor symposia on quantitative biology.
[14] L. Chin,et al. Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation , 2000, Nature Genetics.
[15] Lynda Chin,et al. E.: “A Summary of , 1968 .
[16] J. Griffith,et al. Mammalian Telomeres End in a Large Duplex Loop , 1999, Cell.
[17] E. Blackburn,et al. Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[18] D. Broccoli,et al. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. , 1999, Science.
[19] M. Hande,et al. Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice , 1999, The Journal of cell biology.
[20] K. Kinzler,et al. Genetic instabilities in human cancers , 1998, Nature.
[21] P. Slijepcevic. Telomeres and mechanisms of Robertsonian fusion , 1998, Chromosoma.
[22] R. DePinho,et al. Essential role of mouse telomerase in highly proliferative organs , 1998, Nature.
[23] Robin C. Allshire,et al. Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe , 1998, Nature.
[24] Paul Nurse,et al. Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination , 1998, Nature.
[25] R. Ward,et al. Short telomeres on human chromosome 17p. , 1998 .
[26] R. Ward,et al. Short telomeres on human chromosome 17p , 1998, Nature Genetics.
[27] E. Blackburn,et al. The telomere and telomerase: how do they interact? , 1999, Ciba Foundation symposium.
[28] S. Bacchetti,et al. Reprogramming of telomerase by expression of mutant telomerase RNA template in human cells leads to altered telomeres that correlate with reduced cell viability , 1997, Molecular and cellular biology.
[29] María A Blasco,et al. Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA , 1997, Cell.
[30] D. Broccoli,et al. Human telomeres contain two distinct Myb–related proteins, TRF1 and TRF2 , 1997, Nature Genetics.
[31] J. Sedat,et al. Block in Anaphase Chromosome Separation Caused by a Telomerase Template Mutation , 1997, Science.
[32] Bas van Steensel,et al. Control of telomere length by the human telomeric protein TRF1 , 1997, Nature.
[33] C B Harley,et al. Replicative Senescence and Cell Immortality: The Role of Telomeres and Telomerase , 1997, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[34] F. Ishikawa. [Telomere and telomerase]. , 1996, Human Cell.
[35] Thomas Ried,et al. Multicolour spectral karyotyping of mouse chromosomes , 1996, Nature Genetics.
[36] H. Tanke,et al. Heterogeneity in telomere length of human chromosomes. , 1996, Human molecular genetics.
[37] C. Greider,et al. Telomere length regulation. , 1996, Annual review of biochemistry.
[38] E. Blackburn,et al. Runaway telomere elongation caused by telomerase RNA gene mutations , 1995, Nature.
[39] T. Lange,et al. Activation of telomerase in a human tumor. , 1994 .
[40] T. de Lange. Activation of telomerase in a human tumor. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[41] J. Haber,et al. Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events , 1994, Molecular and cellular biology.
[42] C B Harley,et al. Telomere length predicts replicative capacity of human fibroblasts. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[43] B. Taylor,et al. Mouse minor satellite DNA genetically maps to the centromere and is physically linked to the proximal telomere. , 1991, Genomics.
[44] D. Shore,et al. Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length , 1990, Science.
[45] E. Blackburn,et al. Generation of telomere-length heterogeneity in Saccharomyces cerevisiae. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[46] Carol W. Greider,et al. Identification of a specific telomere terminal transferase activity in tetrahymena extracts , 1985, Cell.
[47] V. Chapman,et al. Construction of a small Mus musculus repetitive DNA library: identification of a new satellite sequence in Mus musculus. , 1983, Nucleic acids research.
[48] D C Ward,et al. Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[49] B. Mcclintock,et al. The Fusion of Broken Ends of Chromosomes Following Nuclear Fusion. , 1942, Proceedings of the National Academy of Sciences of the United States of America.
[50] B. Mcclintock,et al. The Stability of Broken Ends of Chromosomes in Zea Mays. , 1941, Genetics.
[51] B. Mcclintock. The Behavior in Successive Nuclear Divisions of a Chromosome Broken at Meiosis. , 1939, Proceedings of the National Academy of Sciences of the United States of America.