Identification of signal transduction pathways involved in constitutive NF-κB activation in breast cancer cells
暂无分享,去创建一个
[1] Eric Verdin,et al. Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation , 2001, Science.
[2] Michael Karin,et al. Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway , 2001, Science.
[3] E. Lander,et al. Growth Factor-specific Signaling Pathway Stimulation and Gene Expression Mediated by ErbB Receptors* 210 , 2001, The Journal of Biological Chemistry.
[4] Marty W. Mayo,et al. Akt Stimulates the Transactivation Potential of the RelA/p65 Subunit of NF-κB through Utilization of the IκB Kinase and Activation of the Mitogen-activated Protein Kinase p38* , 2001, The Journal of Biological Chemistry.
[5] D. Seldin,et al. Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-kappaB in breast cancer. , 2001, Cancer research.
[6] H. Nakshatri,et al. Repression of GADD153/CHOP by NF-κB: a possible cellular defense against endoplasmic reticulum stress-induced cell death , 2001, Oncogene.
[7] W. Yung,et al. Tumor Suppressor MMAC/PTEN Inhibits Cytokine-induced NFκB Activation without Interfering with the IκB Degradation Pathway* , 2001, The Journal of Biological Chemistry.
[8] C. Gélinas,et al. Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-κB , 2001, Nature Cell Biology.
[9] R. Ratan,et al. The Epidermal Growth Factor Receptor Engages Receptor Interacting Protein and Nuclear Factor-κB (NF-κB)-inducing Kinase to Activate NF-κB , 2001, The Journal of Biological Chemistry.
[10] A. Baldwin. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB , 2001 .
[11] R. Steele,et al. Deceiving appearances: signaling by “dead” and “fractured” receptor protein‐tyrosine kinases , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.
[12] Yosef Yarden,et al. Molecular mechanisms underlying ErbB2/HER2 action in breast cancer , 2000, Oncogene.
[13] G. Sledge,et al. Paclitaxel sensitivity of breast cancer cells with constitutively active NF-κB is enhanced by IκBα super-repressor and parthenolide , 2000, Oncogene.
[14] G. Sledge,et al. Cancer cell-derived interleukin 1alpha contributes to autocrine and paracrine induction of pro-metastatic genes in breast cancer. , 2000, Biochemical and biophysical research communications.
[15] S. Mader,et al. Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis , 2000, Oncogene.
[16] Debajit K. Biswas,et al. Epidermal growth factor-induced nuclear factor κB activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells , 2000 .
[17] Monilola A. Olayioye,et al. The ErbB signaling network: receptor heterodimerization in development and cancer , 2000, The EMBO journal.
[18] J. Russo,et al. Activation of NF-kappaB/Rel occurs early during neoplastic transformation of mammary cells. , 2000, Carcinogenesis.
[19] Richard W. E. Clarkson,et al. NF-κB Inhibits Apoptosis in Murine Mammary Epithelia* , 2000, The Journal of Biological Chemistry.
[20] M. Hung,et al. HER-2/neu Blocks Tumor Necrosis Factor-induced Apoptosis via the Akt/NF-κB Pathway* , 2000, The Journal of Biological Chemistry.
[21] W. Funkhouser,et al. Selective activation of NF-κB subunits in human breast cancer: potential roles for NF-κB2/p52 and for Bcl-3 , 2000, Oncogene.
[22] T. Gilmore,et al. Control of apoptosis by Rel/NF-κB transcription factors , 1999, Oncogene.
[23] B. Rayet,et al. Aberrant rel/nfkb genes and activity in human cancer , 1999, Oncogene.
[24] M. Sliwkowski,et al. Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells , 1999, Oncogene.
[25] L. Pfeffer,et al. NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase , 1999, Nature.
[26] C. Van Waes,et al. The host environment promotes the constitutive activation of nuclear factor-kappaB and proinflammatory cytokine expression during metastatic tumor progression of murine squamous cell carcinoma. , 1999, Cancer research.
[27] G. Stark,et al. Activation of Phosphatidylinositol 3-Kinase in Response to Interleukin-1 Leads to Phosphorylation and Activation of the NF-κB p65/RelA Subunit , 1999, Molecular and Cellular Biology.
[28] H. Nakshatri,et al. Negative Regulation of Transactivation Function but Not DNA Binding of NF-κB and AP-1 by IκBβ1 in Breast Cancer Cells* , 1999, The Journal of Biological Chemistry.
[29] N. Maihle,et al. Isolation and characterization of four alternate c-erbB3 transcripts expressed in ovarian carcinoma-derived cell lines and normal human tissues , 1998, Oncogene.
[30] S. Ghosh,et al. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. , 1998, Molecular cell.
[31] D. Cortez,et al. A requirement for NF-κB activation in Bcr–Abl-mediated transformation , 1998 .
[32] P. W. Janes,et al. Analysis of Grb7 Recruitment by Heregulin-activated erbB Receptors Reveals a Novel Target Selectivity for erbB3* , 1998, The Journal of Biological Chemistry.
[33] P. Leder,et al. Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes , 1998, Oncogene.
[34] D. Stern,et al. Specificity within the EGF family/ErbB receptor family signaling network , 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.
[35] G. Evan,et al. Induction of TNF‐sensitive cellular phenotype by c‐Myc involves p53 and impaired NF‐κB activation , 1997, The EMBO journal.
[36] B. Dörken,et al. Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. , 1997, The Journal of clinical investigation.
[37] A. E. Rogers,et al. Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer. , 1997, The Journal of clinical investigation.
[38] A. Richmond,et al. Enhanced Degradation of I-κBα Contributes to Endogenous Activation of NF-κB in Hs294T Melanoma Cells , 1997 .
[39] G. Sledge,et al. Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth , 1997, Molecular and cellular biology.
[40] Marty W. Mayo,et al. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.
[41] M. Hung,et al. Suppressed transformation and induced differentiation of HER-2/neu-overexpressing breast cancer cells by emodin. , 1995, Cancer research.
[42] C. Der,et al. Aberrant function of the Ras signal transduction pathway in human breast cancer , 1995, Breast Cancer Research and Treatment.
[43] R. Lidereau,et al. Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[44] R. Roeder,et al. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. , 1983, Nucleic acids research.
[45] M J May,et al. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. , 1998, Annual review of immunology.