UTILIZACION DEL ATOMIZADOR INTRANASAL PARA LA ADMINISTRACION DE MIDAZOLAM EN EMERGENCIAS PEDIATRICAS

Introduction: Midazolam administration using an intranasal spray (MAD®) may be efficacious and safe in pediatric emer- gencies. Objectives: 1) To describe midazolam administration using an intranasal atomizer. 2) To assess the complications associated with intranasal midazolam. Methods: Design: A descriptive and prospective study in patients who were ad- ministered midazolam via MAD® between 01/08/2007 and 30/03/2008. Results: Intranasal midazolam was used 28 times in children with a mean age of 38 months (SD 28.44); 64% were boys. Reasons for administrartion were: Procedures in 71.43% (n=20) and seizures in 28.57% (n=8). Procedures: Mean dose used was 0.27 mg/kg (SD 0.35), and mean time to effect onset was 3 minutes (SD 3.5). In febrile seizures, after search for intravenous access had failed, midazolam was administered using MAD® with a mean time interval between seizure onset and drug administration of 3.42 (SD 6.61) min- utes and at a mean dose of 0.3 mg/kg. No complications were observed. Conclusions: 1) Intranasal midazolam administration was safe and efficacious. 2) No complications were observed.