A Compendium of Case Studies that Helped to Shape the REACH Guidance on Chemical Categories and Read Across

This document is a compendium of case studies that were conducted as part of REACH Implementation Project (RIP) 3.3-2, which was charged with developing technical guidance on the use of chemical grouping approaches (chemical categories and read-across methods). The lessons and insights from each of the case studies helped to shape the technical content captured in the resulting guidance document. The case studies are presented in their original form. For ease of reference, they are grouped into two themes: current and prospective experiences in the formation and/or use of category approaches.

[1]  Yoshihiro Kudo,et al.  Automatic log P estimation based on combined additive modeling methods , 1990, J. Comput. Aided Mol. Des..

[2]  Russell O. Potts,et al.  Predicting Skin Permeability , 1992, Pharmaceutical Research.