With the development of missile weapons in the high-tech local wars, higher performance, shorter lifecycle, and lower cost have become the new requirements for missile design. Consequently, an advanced integrated missile design environment is an instant need to provide the technical support. This paper explores some key technologies of this integrated design environment, including architecture, design process integration, data flow integration and application integration. An integrated missile design framework which supports configurable function is put forward, which realizes missilepsilas design-flow customization, data-flow customization, application integration, etc. Finally, an application example verifies the feasibility, effectiveness and practicality of the study results of this paper.