Pigment epithelium-derived factor protects cone photoreceptor-derived 661W cells from light damage through Akt activation.

[1]  A. Reichenbach,et al.  Pigment Epithelium-Derived Factor Released by Müller Glial Cells Exerts Neuroprotective Effects on Retinal Ganglion Cells , 2012, Neurochemical Research.

[2]  P. Grammas,et al.  Pigment epithelium-derived factor (PEDF) protects cortical neurons in vitro from oxidant injury by activation of extracellular signal-regulated kinase (ERK) 1/2 and induction of Bcl-2 , 2012, Neuroscience Research.

[3]  S. Tobimatsu,et al.  Pigment epithelium-derived factor gene therapy targeting retinal ganglion cell injuries: neuroprotection against loss of function in two animal models. , 2011, Human gene therapy.

[4]  I. Pang,et al.  Pigment epithelium-derived factor protects retinal ganglion cells , 2007, BMC Neuroscience.

[5]  Raul Heredia,et al.  Identification of a Lipase-linked Cell Membrane Receptor for Pigment Epithelium-derived Factor* , 2006, Journal of Biological Chemistry.

[6]  S. Becerra Focus on Molecules: Pigment epithelium-derived factor (PEDF). , 2006, Experimental eye research.

[7]  Zhiming Wen,et al.  Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[8]  C. Barnstable,et al.  Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential , 2004, Progress in Retinal and Eye Research.

[9]  Marta García,et al.  Inhibition of Xenografted Human Melanoma Growth and Prevention of Metastasis Development by Dual Antiangiogenic/Antitumor Activities of Pigment Epithelium-Derived Factor , 2004, Cancer Research.

[10]  M. Matsumura,et al.  Decreased levels of pigment epithelium-derived factor in eyes with neuroretinal dystrophic diseases. , 2004, American journal of ophthalmology.

[11]  P. Campochiaro,et al.  Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis. , 2004, American journal of ophthalmology.

[12]  M. Naash,et al.  Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice. , 2004, Investigative ophthalmology & visual science.

[13]  L. Montuenga,et al.  Pigment epithelium-derived factor in the monkey retinal pigment epithelium and interphotoreceptor matrix: apical secretion and distribution. , 2004, Experimental eye research.

[14]  E. Duh,et al.  Retinal neuroprotection against ischemic injury mediated by intraocular gene transfer of pigment epithelium-derived factor. , 2003, Investigative ophthalmology & visual science.

[15]  J. Prieto,et al.  Suppression of angiogenesis and tumor growth by adenoviral-mediated gene transfer of pigment epithelium-derived factor. , 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

[16]  O. Volpert,et al.  Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration. , 2002, American journal of ophthalmology.

[17]  N. Bouck PEDF: anti-angiogenic guardian of ocular function. , 2002, Trends in molecular medicine.

[18]  Peter Gehlbach,et al.  Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. , 2002, Investigative ophthalmology & visual science.

[19]  O. Volpert,et al.  Pigment epithelium-derived factor (PEDF) in neuroblastoma: a multifunctional mediator of Schwann cell antitumor activity. , 2001, Journal of cell science.

[20]  J. Tombran-Tink,et al.  In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor. , 2001, Investigative ophthalmology & visual science.

[21]  Kanji A. Takahashi,et al.  Pigment epithelium derived factor as a neuroprotective agent against ischemic retinal injury , 2001, Current eye research.

[22]  C. Gravel,et al.  Pigment Epithelium-Derived Factor Delays the Death of Photoreceptors in Mouse Models of Inherited Retinal Degenerations , 1999, Neurobiology of Disease.

[23]  W. Benedict,et al.  Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. , 1999, Science.

[24]  R. Kuncl,et al.  Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration. , 1999, Journal of neuropathology and experimental neurology.

[25]  P. Campochiaro,et al.  Sequence and expression analysis of bovine pigment epithelium-derived factor. , 1998, Biochimica et biophysica acta.

[26]  G. Chader,et al.  Identification of pigment epithelium-derived factor in the interphotoreceptor matrix of bovine eyes. , 1995, Protein expression and purification.

[27]  D. Bok,et al.  Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[28]  S. Becerra,et al.  Pigment epithelium-derived factor receptor (PEDF-R): a plasma membrane-linked phospholipase with PEDF binding affinity. , 2010, Advances in experimental medicine and biology.

[29]  Jian-xing Ma,et al.  Light induces programmed cell death by activating multiple independent proteases in a cone photoreceptor cell line. , 2007, Investigative ophthalmology & visual science.