Mammogram-Based Cancer Detection Using Deep Convolutional Neural Networks

In recent years, applying deep learning to medical images has experienced a surge but often comes with limitations related to the datasets: publicly available datasets have the drawback of being relatively small compared to other datasets used in image recognition tasks. We show multiple findings in our work: the immense power of Deep Convolutional Neural Networks even when applied on a small dataset such as the INbreast dataset. We also demonstrate that accuracy is not the only evaluation metric for network performance evaluation: the recall metric should be maximized. We also show the importance of using cross-validation to assure the absence of overfitting during the learning process. Results show an average classification accuracy for 5-fold cross-validation of 80.10% and an average AUC of 0.78. A graphical user interface was implemented in order to be tested by certified radiologists.

[1]  Salsabil Amin El-Regaily,et al.  Lung nodule segmentation and detection in computed tomography , 2017, 2017 Eighth International Conference on Intelligent Computing and Information Systems (ICICIS).

[2]  Ian W. Ricketts,et al.  The Mammographic Image Analysis Society digital mammogram database , 1994 .

[3]  Li Shen,et al.  End-to-end Training for Whole Image Breast Cancer Diagnosis using An All Convolutional Design , 2017, ArXiv.

[4]  Daniel Lévy,et al.  Breast Mass Classification from Mammograms using Deep Convolutional Neural Networks , 2016, ArXiv.

[5]  Mohammed A.-M. Salem,et al.  Survey of Computer Aided Detection Systems for Lung Cancer in Computed Tomography , 2017 .

[6]  D. Montoya-Zapata,et al.  Detection and Diagnosis of Breast Tumors using Deep Convolutional Neural Networks , 2016 .

[7]  Kyunghyun Cho,et al.  High-Resolution Breast Cancer Screening with Multi-View Deep Convolutional Neural Networks , 2017, ArXiv.

[8]  Daniel C. Moura,et al.  BCDR : A BREAST CANCER DIGITAL REPOSITORY , 2012 .

[9]  Jaime S. Cardoso,et al.  INbreast: toward a full-field digital mammographic database. , 2012, Academic radiology.

[10]  Andrew Zisserman,et al.  Return of the Devil in the Details: Delving Deep into Convolutional Nets , 2014, BMVC.

[11]  Mohammed A.-M. Salem,et al.  Intelligent organization of multiuser photo galleries using sub-event detection , 2017, 2017 12th International Conference on Computer Engineering and Systems (ICCES).

[12]  Gaël Varoquaux,et al.  Scikit-learn: Machine Learning in Python , 2011, J. Mach. Learn. Res..

[13]  Subhransu Maji,et al.  Multi-view Convolutional Neural Networks for 3D Shape Recognition , 2015, 2015 IEEE International Conference on Computer Vision (ICCV).

[14]  Selma Ayşe Özel,et al.  Using deep learning for mammography classification , 2017, 2017 International Conference on Computer Science and Engineering (UBMK).

[15]  Miguel Ángel Guevara-López,et al.  Representation learning for mammography mass lesion classification with convolutional neural networks , 2016, Comput. Methods Programs Biomed..

[16]  Mohammed A.-M. Salem,et al.  Recent Survey on Medical Image Segmentation , 2017 .

[17]  Gustavo Carneiro,et al.  Unregistered Multiview Mammogram Analysis with Pre-trained Deep Learning Models , 2015, MICCAI.