Loss of heterozygosity reveals non-VHL allelic loss in hemangioblastomas at 22q13.
暂无分享,去创建一个
[1] A. Vortmeyer,et al. Developmental arrest of angioblastic lineage initiates tumorigenesis in von Hippel-Lindau disease. , 2003, Cancer research.
[2] M. Hoang,et al. Inhibin Alpha Distinguishes Hemangioblastoma From Clear Cell Renal Cell Carcinoma , 2003, The American journal of surgical pathology.
[3] J. Prchal,et al. Mutations of von Hippel-Lindau tumor-suppressor gene and congenital polycythemia. , 2003, American journal of human genetics.
[4] J. Gnarra,et al. Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth. , 2003, Cancer cell.
[5] G. Reifenberger,et al. Genetic Alterations Commonly Found in Diffusely Infiltrating Cerebral Gliomas Are Rare or Absent in Pleomorphic Xanthoastrocytomas , 2002, Journal of neuropathology and experimental neurology.
[6] A. Vortmeyer,et al. New Insights into the Genetics of Familial Chromaffin Cell Tumors , 2002, Annals of the New York Academy of Sciences.
[7] J. Biegel,et al. Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System: Report on Workshop , 2002, Journal of pediatric hematology/oncology.
[8] I. Nishimoto,et al. Distinct regions of loss of heterozygosity on 22q in different sites of head and neck squamous cell carcinomas. , 2002, Medical science monitor : international medical journal of experimental and clinical research.
[9] M. Alonso,et al. Loss of chromosome 22 and absence of NF2 gene mutation in a case of multiple meningiomas. , 2002, Human pathology.
[10] J. Tonn,et al. Loss of heterozygosity on chromosome 22 in human ependymomas , 2002, Acta Neuropathologica.
[11] A. Wild,et al. A novel insulinoma tumor suppressor gene locus on chromosome 22q with potential prognostic implications. , 2001, The Journal of clinical endocrinology and metabolism.
[12] E. Zwarthoff,et al. Truncated NF2 proteins are not detected in meningiomas and schwannomas , 2001, Neuropathology : official journal of the Japanese Society of Neuropathology.
[13] A. von Deimling,et al. Indications for a tumor suppressor gene at 22q11 involved in the pathogenesis of ependymal tumors and distinct from hSNF5/INI1 , 2001, Acta Neuropathologica.
[14] P. Wesseling,et al. Characteristic Chromosomal Aberrations in Sporadic Cerebellar Hemangioblastomas Revealed by Comparative Genomic Hybridization , 2001, Journal of Neuro-Oncology.
[15] A. von Deimling,et al. Mutational analysis of INI1 in sporadic human brain tumors , 2001, Acta Neuropathologica.
[16] Hyun B Choi,et al. Erythropoietin and Erythropoietin Receptors in Human CNS Neurons, Astrocytes, Microglia, and Oligodendrocytes Grown in Culture , 2001, Journal of neuropathology and experimental neurology.
[17] R. Sciot,et al. The neurofibromatosis type 2 gene is mutated in perineurial cell tumors: a molecular genetic study of eight cases. , 2001, The American journal of pathology.
[18] W. Kaelin,et al. The von Hippel-Lindau tumor suppressor gene. , 2001, Experimental cell research.
[19] W. Brück,et al. Erythropoietin and erythropoietin receptor in human ischemic/hypoxic brain , 2001, Acta Neuropathologica.
[20] C. Eng,et al. Differential genetic alterations in von Hippel-Lindau syndrome-associated and sporadic pheochromocytomas. , 2000, The Journal of clinical endocrinology and metabolism.
[21] Till Acker,et al. Up-regulation of hypoxia-inducible factors HIF-1α and HIF-2α under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function , 2000, Oncogene.
[22] A. Vortmeyer,et al. Somatic von Hippel-Lindau gene mutations detected in sporadic endolymphatic sac tumors. , 2000, Cancer research.
[23] K. Plate,et al. VEGF in Brain Tumors , 2000, Journal of Neuro-Oncology.
[24] T. Hulsebos,et al. A region of common deletion in 22q13.3 in human glioma associated with astrocytoma progression , 2000, International journal of cancer.
[25] G. Perilongo,et al. Somatic mosaicism in von Hippel‐Lindau disease , 2000, Human mutation.
[26] K. Hoang-Xuan,et al. Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations. , 1999, Human molecular genetics.
[27] A. Gregor,et al. Angiogenic histogenesis of stromal cells in hemangioblastoma: ultrastructural and immunohistochemical study. , 1999, Ultrastructural pathology.
[28] S. Richard,et al. [Neuro-endocrine tumors and von Hippel-Lindau disease. 3 cases]. , 1999, Presse medicale.
[29] C. Wykoff,et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis , 1999, Nature.
[30] A. Vortmeyer,et al. VHL gene deletion and enhanced VEGF gene expression detected in the stromal cells of retinal angioma. , 1999, Archives of ophthalmology.
[31] J. Krupiński,et al. Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke. , 1999, Laboratory investigation; a journal of technical methods and pathology.
[32] J. Rosenstein,et al. VEGF mRNA and Its Receptorflt-1Are Expressed in Reactive Astrocytes Following Neural Grafting and Tumor Cell Implantation in the Adult CNS , 1998, Experimental Neurology.
[33] K. Plate,et al. Coexpression of erythropoietin and vascular endothelial growth factor in nervous system tumors associated with von Hippel-Lindau tumor suppressor gene loss of function , 1998 .
[34] M. Golubić,et al. Immunoblotting analysis of schwannomin/merlin in human schwannomas. , 1998, The American journal of otology.
[35] Olivier Delattre,et al. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer , 1998, Nature.
[36] K. Plate,et al. Up-Regulation of Vascular Endothelial Growth Factor in Stromal Cells of Hemangioblastomas Is Correlated with Up-Regulation of the Transcription Factor HRF/HIF-2α , 1998 .
[37] S. Curley,et al. Surgical decision-making affected by clinical and genetic screening of a novel kindred with von Hippel-Lindau disease and pancreatic islet cell tumors. , 1998, Annals of surgery.
[38] W. Linehan,et al. Loss of heterozygosity and somatic mutations of the VHL tumor suppressor gene in sporadic cerebellar hemangioblastomas. , 1998, Cancer research.
[39] M. Emmert-Buck,et al. von Hippel-Lindau gene deletion detected in the stromal cell component of a cerebellar hemangioblastoma associated with von Hippel-Lindau disease. , 1997, Human pathology.
[40] W. Poon,et al. Molecular genetic analysis of the von Hippel-Lindau disease tumor suppressor gene in familial and sporadic cerebellar hemangioblastomas. , 1997, American journal of clinical pathology.
[41] S. Pulst,et al. Immunohistochemical Detection of Schwannomin and Neurofibromin in Vestibular Schwannomas, Ependymomas and Meningiomas , 1997, Journal of neuropathology and experimental neurology.
[42] Satoshi O. Suzuki,et al. Expression of neurofibromatosis 2 protein in human brain tumors: an immunohistochemical study , 1997, Acta Neuropathologica.
[43] S. Masuda,et al. Insulin-like growth factors and insulin stimulate erythropoietin production in primary cultured astrocytes , 1997, Brain Research.
[44] A. Paetau,et al. Different expression of adhesion molecules on stromal cells and endothelial cells of capillary hemangioblastoma , 1996, Acta Neuropathologica.
[45] K. Plate,et al. Pathology, genetics and cell biology of hemangioblastomas. , 1996, Histology and histopathology.
[46] J. Bruce,et al. Frequent type 2 neurofibromatosis gene transcript mutations in sporadic intramedullary spinal cord ependymomas. , 1996, Neurosurgery.
[47] G. Reifenberger,et al. MUTATION OF THE VON HIPPEL–LINDAU TUMOUR SUPPRESSOR GENE IN CAPILLARY HAEMANGIOBLASTOMAS OF THE CENTRAL NERVOUS SYSTEM , 1996, The Journal of pathology.
[48] F. Vitelli,et al. Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas , 1996, Human Genetics.
[49] M. Gassmann,et al. Erythropoietin Gene Expression in Human, Monkey and Murine Brain , 1996, The European journal of neuroscience.
[50] K. Alitalo,et al. Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas. , 1996, The American journal of pathology.
[51] W. Poon,et al. Combined molecular genetic studies of chromosome 22q and the neurofibromatosis type 2 gene in central nervous system tumors. , 1995, Neurosurgery.
[52] J. Minna,et al. Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer. , 1995, Cancer research.
[53] K. Plate,et al. Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas. , 1995, Cancer research.
[54] T. Shuin,et al. Somatic mutations of the von Hippel-Lindau tumor suppressor gene in sporadic central nervous system hemangioblastomas. , 1994, Cancer research.
[55] K. Yamagishi,et al. A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes. , 1994, The Journal of biological chemistry.
[56] H. Nagase,et al. Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers. , 1994, Human molecular genetics.
[57] J. Gusella,et al. Exon scanning for mutation of the NF2 gene in schwannomas. , 1994, Human molecular genetics.
[58] J. Gnarra,et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. , 1993, Science.
[59] J. Rey,et al. Involvement of 22q12 in a neurofibrosarcoma in neurofibromatosis type 1. , 1993, Cancer genetics and cytogenetics.
[60] J. Rey,et al. Abnormalities of chromosome 22 in human brain tumors determined by combined cytogenetic and molecular genetic approaches. , 1993, Cancer genetics and cytogenetics.
[61] Xu Qw,et al. [Hemangioblastoma of the central nervous system]. , 1989, Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry.
[62] Y. Nakamura,et al. Specific genetic change in tumors associated with von Hippel-Lindau disease. , 1989, Journal of the National Cancer Institute.
[63] L. True,et al. Immunohistochemistry of Capillary Hemangioblastoma: Immunoperoxidase‐Labeled Antibody Staining Resolves the Differential Diagnosis with Metastatic Renal Cell Carcinoma, But Does Not Explain the Histogenesis of the Capillary Hemangioblastoma , 1989, The American journal of surgical pathology.
[64] W. Paulus,et al. Histogenesis of stromal cells in cerebellar hemangioblastomas. An immunohistochemical study. , 1989, The American journal of pathology.
[65] A. Tanimura,et al. Hemangioblastoma of the central nervous system: nature of the stromal cells as studied by the immunoperoxidase technique. , 1984, Human pathology.
[66] A. Chaudhry,et al. Ultrastructure of cerebellar hemangioblastoma , 1978, Cancer.
[67] K. Tory,et al. Molecular genetic investigations of the mechanism of tumourigenesis in von Hippel-Lindau disease: analysis of allele loss in VHL tumours , 2004, Human Genetics.
[68] P. Mckeever,et al. Selective localization of γ-enolase in stromal cells of cerebellar hemangioblastomas , 2004, Acta Neuropathologica.
[69] E. Oldfield,et al. The natural history of hemangioblastomas of the central nervous system in patients with von Hippel-Lindau disease. , 2003, Journal of neurosurgery.
[70] J. Rey,et al. Chromosomal abnormalities in pituitary adenomas. , 2001, Cancer genetics and cytogenetics.
[71] M. Beckner. Factors promoting tumor angiogenesis. , 1999, Cancer investigation.
[72] G. Thomas,et al. Germline mutation profile of the VHL gene in von Hippel‐Lindau disease and in sporadic hemangioblastoma , 1998, Human mutation.
[73] J. Rey,et al. Cytogenetics and molecular genetics of nervous system tumors. , 1992, Oncology research.
[74] P. Gallagher,et al. Haemangioblastoma , 2004, Acta Neuropathologica.